Yongsung Kim
Yongsung Kim
University of Michigan Medical School
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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
J Park, SB Lee, S Lee, Y Kim, S Song, S Kim, E Bae, J Kim, M Shong, ...
Nature 441 (7097), 1157-1161, 2006
Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects
J Mertens, ACM Paquola, M Ku, E Hatch, L Böhnke, S Ladjevardi, ...
Cell stem cell 17 (6), 705-718, 2015
Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation
X Zheng, L Boyer, M Jin, J Mertens, Y Kim, L Ma, M Hamm, FH Gage, ...
eLife 5, e13374, 2016
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
J Mertens, QW Wang, Y Kim, DX Yu, S Pham, B Yang, Y Zheng, ...
Nature 527 (7576), 95-99, 2015
Energy-dependent regulation of cell structure by AMP-activated protein kinase
JH Lee, H Koh, M Kim, Y Kim, SY Lee, RE Karess, SH Lee, M Shong, ...
Nature 447 (7147), 1017-1020, 2007
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
Y Kim, J Park, S Kim, S Song, SK Kwon, SH Lee, T Kitada, JM Kim, ...
Biochemical and biophysical research communications 377 (3), 975-980, 2008
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
K Brennand, JN Savas, Y Kim, N Tran, A Simone, K Hashimoto-Torii, ...
Molecular psychiatry 20 (3), 361-368, 2015
Aging in a dish: iPSC-derived and directly induced neurons for studying brain aging and age-related neurodegenerative diseases
J Mertens, D Reid, S Lau, Y Kim, FH Gage
Annual review of genetics 52, 271-293, 2018
ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase
SB Lee, S Kim, J Lee, J Park, G Lee, Y Kim, JM Kim, J Chung
EMBO reports 8 (4), 360-365, 2007
Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration
X Zheng, L Boyer, M Jin, Y Kim, W Fan, C Bardy, T Berggren, RM Evans, ...
eLife 5, e13378, 2016
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
D Sun, G Lee, JH Lee, HY Kim, HW Rhee, SY Park, KJ Kim, Y Kim, ...
Nature structural & molecular biology 17 (10), 1188-1194, 2010
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons
V Hook, KJ Brennand, Y Kim, T Toneff, L Funkelstein, KC Lee, M Ziegler, ...
Stem cell reports 3 (4), 531-538, 2014
Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile
Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ...
Cell reports 23 (9), 2550-2558, 2018
Mitochondrial dysfunction and Parkinson’s disease genes: insights from Drosophila
J Park, Y Kim, J Chung
Disease models & mechanisms 2 (7-8), 336-340, 2009
Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease
L Traxler, JR Herdy, D Stefanoni, S Eichhorner, S Pelucchi, A Szücs, ...
Cell Metabolism 34 (9), 1248-1263. e6, 2022
Drosophila Porin/VDAC Affects Mitochondrial Morphology
J Park, Y Kim, S Choi, H Koh, SH Lee, JM Kim, J Chung
PLOS one 5 (10), e13151, 2010
Chemical modulation of transcriptionally enriched signaling pathways to optimize conversion of fibroblasts into neurons
J Herdy, S Schafer, Y Kim, Z Ansari, D Zangwill, M Ku, A Paquola, H Lee, ...
eLife 8, e41356, 2019
Regulation of FOXO1 by TAK1-Nemo-like kinase pathway
S Kim, Y Kim, J Lee, J Chung
Journal of biological chemistry 285 (11), 8122-8129, 2010
Mechanisms underlying the hyperexcitability of CA3 and dentate gyrus hippocampal neurons derived from patients with bipolar disorder
S Stern, A Sarkar, T Stern, A Mei, APD Mendes, Y Stern, G Goldberg, ...
Biological psychiatry 88 (2), 139-149, 2020
Simultaneous loss of TSC1 and DEPDC5 in skeletal and cardiac muscles produces early-onset myopathy and cardiac dysfunction associated with oxidative damage and SQSTM1/p62 …
CS Cho, Y Kim, SR Park, B Kim, C Davis, I Hwang, SV Brooks, JH Lee, ...
Autophagy 18 (10), 2303-2322, 2022
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