Jerome Mertens
TitleCited byYear
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ...
Nature neuroscience 18 (9), 1226, 2015
3232015
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease
P Koch, P Breuer, M Peitz, J Jungverdorben, J Kesavan, D Poppe, J Doerr, ...
Nature 480 (7378), 543, 2011
2612011
Small molecules enable highly efficient neuronal conversion of human fibroblasts
J Ladewig, J Mertens, J Kesavan, J Doerr, D Poppe, F Glaue, S Herms, ...
Nature methods 9 (6), 575, 2012
2592012
Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects
J Mertens, ACM Paquola, M Ku, E Hatch, L Böhnke, S Ladjevardi, ...
Cell stem cell 17 (6), 705-718, 2015
2542015
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
J Mertens, QW Wang, Y Kim, XY Diana, S Pham, B Yang, Y Zheng, ...
Nature 527 (7576), 95, 2015
2262015
Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro
C Bardy, M Van Den Hurk, T Eames, C Marchand, RV Hernandez, ...
Proceedings of the National Academy of Sciences 112 (20), E2725-E2734, 2015
1412015
Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation
X Zheng, L Boyer, M Jin, J Mertens, Y Kim, L Ma, M Hamm, FH Gage, ...
Elife 5, e13374, 2016
1322016
Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience
J Mertens, MC Marchetto, C Bardy, FH Gage
Nature Reviews Neuroscience 17 (7), 424, 2016
1302016
Presenilin-1 L166P mutant human pluripotent stem cell–derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation
P Koch, IY Tamboli, J Mertens, P Wunderlich, J Ladewig, K Stüber, ...
The American journal of pathology 180 (6), 2404-2416, 2012
932012
Generation of functional human serotonergic neurons from fibroblasts
KC Vadodaria, J Mertens, A Paquola, C Bardy, X Li, R Jappelli, L Fung, ...
Molecular psychiatry 21 (1), 49, 2016
632016
APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation
J Mertens, K Stüber, P Wunderlich, J Ladewig, JC Kesavan, ...
Stem Cell Reports 1 (6), 491-498, 2013
542013
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease
B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ...
Neuron 99 (5), 925-940. e7, 2018
422018
Targeting the Cytosolic Innate Immune Receptors RIG‐I and MDA5 Effectively Counteracts Cancer Cell Heterogeneity in Glioblastoma
M Glas, C Coch, D Trageser, J DAßLER, M Simon, P Koch, J Mertens, ...
Stem cells 31 (6), 1064-1074, 2013
362013
The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample
KJ Oedegaard, M Alda, A Anand, OA Andreassen, Y Balaraman, ...
BMC psychiatry 16 (1), 129, 2016
332016
Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells
T Toda, JY Hsu, SB Linker, L Hu, ST Schafer, J Mertens, FV Jacinto, ...
Cell Stem Cell 21 (5), 618-634. e7, 2017
322017
Embryonic Stem Cell–Based Modeling of Tau Pathology in Human Neurons
J Mertens, K Stüber, D Poppe, J Doerr, J Ladewig, O Brüstle, P Koch
The American journal of pathology 182 (5), 1769-1779, 2013
282013
Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons
ST Schafer, ACM Paquola, S Stern, D Gosselin, M Ku, M Pena, TJM Kuret, ...
Nature neuroscience 22 (2), 243, 2019
272019
Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile
Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ...
Cell reports 23 (9), 2550-2558, 2018
262018
Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71
S Mitschka, T Ulas, T Goller, K Schneider, A Egert, J Mertens, O Brüstle, ...
Scientific reports 5, 11126, 2015
182015
Aging in a dish: iPSC-derived and directly induced neurons for studying brain aging and age-related neurodegenerative diseases
J Mertens, D Reid, S Lau, Y Kim, FH Gage
Annual review of genetics 52, 271-293, 2018
172018
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Articles 1–20