A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis TA Down, VK Rakyan, DJ Turner, P Flicek, H Li, E Kulesha, S Graef, ... Nature biotechnology 26 (7), 779-785, 2008 | 789 | 2008 |
Ewing sarcoma TGP Grünewald, F Cidre-Aranaz, D Surdez, EM Tomazou, E de Álava, ... Nature reviews Disease primers 4 (1), 5, 2018 | 726 | 2018 |
Quantitative comparison of genome-wide DNA methylation mapping technologies C Bock, EM Tomazou, AB Brinkman, F Müller, F Simmer, H Gu, N Jäger, ... Nature biotechnology 28 (10), 1106-1114, 2010 | 643 | 2010 |
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs) VK Rakyan, TA Down, NP Thorne, P Flicek, E Kulesha, S Gräf, ... Genome research 18 (9), 1518-1529, 2008 | 433 | 2008 |
Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution H Gu, C Bock, TS Mikkelsen, N Jäger, ZD Smith, E Tomazou, A Gnirke, ... Nature methods 7 (2), 133-136, 2010 | 371 | 2010 |
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma NC Sheffield, G Pierron, J Klughammer, P Datlinger, A Schönegger, ... Nature medicine 23 (3), 386-395, 2017 | 234 | 2017 |
Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1 EM Tomazou, NC Sheffield, C Schmidl, M Schuster, A Schönegger, ... Cell reports 10 (7), 1082-1095, 2015 | 226 | 2015 |
Sarcoma treatment in the era of molecular medicine TGP Grünewald, M Alonso, S Avnet, A Banito, S Burdach, F Cidre‐Aranaz, ... EMBO molecular medicine 12 (11), e11131, 2020 | 209 | 2020 |
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden P Peneder, AM Stütz, D Surdez, M Krumbholz, S Semper, M Chicard, ... Nature communications 12 (1), 3230, 2021 | 128 | 2021 |
Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs LK Svoboda, A Harris, NJ Bailey, R Schwentner, E Tomazou, ... Epigenetics 9 (12), 1613-1625, 2014 | 76 | 2014 |
Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression S Terlecki-Zaniewicz, T Humer, T Eder, J Schmoellerl, E Heyes, ... Nature structural & molecular biology 28 (2), 190-201, 2021 | 71 | 2021 |
EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma AM Katschnig, MO Kauer, R Schwentner, EM Tomazou, CN Mutz, ... Oncogene 36 (43), 5995-6005, 2017 | 60 | 2017 |
EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex SP Selvanathan, GT Graham, AR Grego, TM Baker, JR Hogg, M Simpson, ... Nucleic acids research 47 (18), 9619-9636, 2019 | 50 | 2019 |
Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex D Ottaviani, E Lever, R Mitter, T Jones, T Forshew, R Christova, ... Genome research 18 (11), 1778-1786, 2008 | 38 | 2008 |
Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis EM Tomazou, VK Rakyan, G Lefebvre, R Andrews, P Ellis, DK Jackson, ... BMC Medical Genomics 1, 1-16, 2008 | 34 | 2008 |
RETRACTED ARTICLE: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation T Javaheri, Z Kazemi, J Pencik, HTT Pham, M Kauer, R Noorizadeh, ... Cell death & disease 7 (10), e2419-e2419, 2016 | 25 | 2016 |
Look who's talking too: graduates developing skills through communication EM Tomazou, GT Powell Nature Reviews Genetics 8 (9), 724-726, 2007 | 22 | 2007 |
Quantification of translocation-specific ctDNA provides an integrating parameter for early assessment of treatment response and risk stratification in Ewing sarcoma M Krumbholz, J Eiblwieser, A Ranft, J Zierk, C Schmidkonz, AM Stütz, ... Clinical Cancer Research 27 (21), 5922-5930, 2021 | 19 | 2021 |
MIRA: an R package for DNA methylation-based inference of regulatory activity JT Lawson, EM Tomazou, C Bock, NC Sheffield Bioinformatics 34 (15), 2649-2650, 2018 | 18 | 2018 |
Genome-wide mapping of DNA methylation: a quantitative technology comparison C Bock, EM Tomazou, A Brinkman, F Müller, F Simmer, H Gu, N Jäger, ... Nature biotechnology 28 (10), 1106, 2010 | 18 | 2010 |