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Kate Beckham
Kate Beckham
Verified email at newcastle.ac.uk
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Year
Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis
KSH Beckham, L Ciccarelli, CM Bunduc, HDT Mertens, R Ummels, ...
Nature microbiology 2 (6), 1-7, 2017
1292017
Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds
D Wang, CE Zetterström, M Gabrielsen, KSH Beckham, JJ Tree, ...
Journal of Biological Chemistry 286 (34), 29922-29931, 2011
1082011
An NAD+ phosphorylase toxin triggers Mycobacterium tuberculosis cell death
DM Freire, C Gutierrez, A Garza-Garcia, AD Grabowska, AJ Sala, ...
Molecular cell 73 (6), 1282-1291. e8, 2019
642019
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7
KSH Beckham, JPR Connolly, JM Ritchie, D Wang, JA Gawthorne, ...
Molecular microbiology 93 (1), 199-211, 2014
532014
Structure of the mycobacterial ESX-5 type VII secretion system pore complex
KSH Beckham, C Ritter, G Chojnowski, DS Ziemianowicz, E Mullapudi, ...
Science advances 7 (26), eabg9923, 2021
452021
Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification
JA Gawthorne, LE Reddick, SN Akpunarlieva, KSH Beckham, JM Christie, ...
Plos one 7 (12), e52962, 2012
412012
Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103+CD11b+ DCs in the intestinal lamina propria
CL Scott, TFP Zangerle Murray, KSH Beckham, G Douce, AMI Mowat
European journal of immunology 44 (12), 3658-3668, 2014
362014
From screen to target: insights and approaches for the development of anti-virulence compounds
KSH Beckham, AJ Roe
Frontiers in Cellular and Infection Microbiology 4, 139, 2014
242014
Structural characterisation of Tpx from Yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds
M Gabrielsen, KSH Beckham, VA Feher, CE Zetterström, D Wang, ...
PLoS One 7 (2), e32217, 2012
212012
Conserved and specialized functions of Type VII secretion systems in non-tuberculous mycobacteria
M Lagune, C Petit, FV Sotomayor, MD Johansen, KSH Beckham, C Ritter, ...
Microbiology 167 (7), 001054, 2021
152021
The ATPases of the mycobacterial type VII secretion system: Structural and mechanistic insights into secretion
TD Crosskey, KSH Beckham, M Wilmanns
Progress in Biophysics and Molecular Biology 152, 25-34, 2020
152020
Formate–nitrite transporters: Optimisation of expression, purification and analysis of prokaryotic and eukaryotic representatives
KSH Beckham, JA Potter, SE Unkles
Protein expression and purification 71 (2), 184-189, 2010
132010
Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis
M Gabrielsen, CE Zetterström, D Wang, KSH Beckham, M Elofsson, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
92010
The pMy vector series: A versatile cloning platform for the recombinant production of mycobacterial proteins in Mycobacterium smegmatis
KSH Beckham, S Staack, M Wilmanns, AHA Parret
Protein Science 29 (12), 2528-2537, 2020
72020
Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex
KSH Beckham, C Ritter, G Chojnowski, E Mullapudi, M Rettel, ...
bioRxiv, 2020.11. 17.387225, 2020
72020
C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus
L Paulowski, KSH Beckham, MD Johansen, L Berneking, N Van, ...
PNAS nexus 1 (4), pgac130, 2022
62022
The structure of an orthorhombic crystal form of aforced reduced'thiol peroxidase reveals lattice formation aided by the presence of the affinity tag
KSH Beckham, O Byron, AJ Roe, M Gabrielsen
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012
32012
FolX from Pseudomonas aeruginosa is octameric in both crystal and solution
M Gabrielsen, KSH Beckham, RJ Cogdell, O Byron, AJ Roe
FEBS letters 586 (8), 1160-1165, 2012
32012
High-Throughput Methods for the Identification of Protein Purification Conditions Using a Cleavable Tag System
M Gabrielsen, KSH Beckham, AJ Roe
Methods in cell biology 112, 93-110, 2012
22012
Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved …
R Zambelloni, KSH Beckham, HJ Wu, M Elofsson, R Marquez, ...
Microbiology 168 (7), 001211, 2022
12022
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