Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data F Finotello, C Mayer, C Plattner, G Laschober, D Rieder, H Hackl, ... Genome medicine 11, 1-20, 2019 | 1130 | 2019 |
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects NL de Vries, J van de Haar, V Veninga, M Chalabi, ME Ijsselsteijn, ... Nature 613 (7945), 743-750, 2023 | 176 | 2023 |
A 40-marker panel for high dimensional characterization of cancer immune microenvironments by imaging mass cytometry ME Ijsselsteijn, R van der Breggen, A Farina Sarasqueta, F Koning, ... Frontiers in immunology 10, 2534, 2019 | 155 | 2019 |
Iron loading is a prominent feature of activated microglia in Alzheimer’s disease patients B Kenkhuis, A Somarakis, L de Haan, O Dzyubachyk, ME IJsselsteijn, ... Acta neuropathologica communications 9, 1-15, 2021 | 137 | 2021 |
High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity NL De Vries, V Van Unen, ME Ijsselsteijn, T Abdelaal, R Van Der Breggen, ... Gut 69 (4), 691-703, 2020 | 129 | 2020 |
Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4 J Van Den Bulk, EME Verdegaal, D Ruano, ME Ijsselsteijn, M Visser, ... Genome medicine 11, 1-15, 2019 | 62 | 2019 |
Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial YL Verschoor, J van de Haar, JG van den Berg, JW van Sandick, ... Nature medicine 30 (2), 519-530, 2024 | 48 | 2024 |
Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis J Roelands, M Van der Ploeg, ME Ijsselsteijn, H Dang, JJ Boonstra, ... Gut 72 (7), 1326-1339, 2023 | 47 | 2023 |
Cancer immunophenotyping by seven‐colour multispectral imaging without tyramide signal amplification ME Ijsselsteijn, TP Brouwer, Z Abdulrahman, E Reidy, A Ramalheiro, ... The Journal of Pathology: Clinical Research 5 (1), 3-11, 2019 | 47 | 2019 |
Colorectal cancer: a paradigmatic model for cancer immunology and immunotherapy ME IJsselsteijn, R Sanz-Pamplona, F Hermitte, NFCC de Miranda Molecular aspects of medicine 69, 123-129, 2019 | 46 | 2019 |
Revisiting immune escape in colorectal cancer in the era of immunotherapy ME Ijsselsteijn, F Petitprez, L Lacroix, D Ruano, R van Der Breggen, ... British journal of cancer 120 (8), 815-818, 2019 | 42 | 2019 |
Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data. Genome Med. 2019; 11: 34 F Finotello, C Mayer, C Plattner, G Laschober, D Rieder, H Hackl, ... | 42 | 2019 |
A 34-marker panel for imaging mass cytometric analysis of human snap-frozen tissue N Guo, V Van Unen, ME Ijsselsteijn, LF Ouboter, AE Van der Meulen, ... Frontiers in immunology 11, 1466, 2020 | 35 | 2020 |
Semi‐automated background removal limits data loss and normalizes imaging mass cytometry data ME Ijsselsteijn, A Somarakis, BPF Lelieveldt, T Höllt, NFCC de Miranda Cytometry Part A 99 (12), 1187-1197, 2021 | 32 | 2021 |
Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival Z Abdulrahman, SJ Santegoets, G Sturm, P Charoentong, ME Ijsselsteijn, ... Journal for Immunotherapy of Cancer 10 (2), 2022 | 31 | 2022 |
Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface J Krop, A van der Zwan, ME Ijsselsteijn, H Kapsenberg, SJ Luk, ... Iscience 25 (7), 2022 | 25 | 2022 |
Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape MA Glaire, NAJ Ryan, ME Ijsselsteijn, K Kedzierska, S Obolenski, R Ali, ... The Journal of pathology 257 (3), 340-351, 2022 | 22 | 2022 |
Visual cohort comparison for spatial single-cell omics-data TH Antonios Somarakis, Marieke E Ijsselsteijn, Sietse J Luk, Boyd Kenkhuis ... IEEE Trans Vis Comput Graph . 27 (2), 733-743, 2021 | 19* | 2021 |
CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden J Van Den Bulk, M Van Der Ploeg, ME Ijsselsteijn, D Ruano, ... Journal for immunotherapy of cancer 11 (2), 2023 | 17 | 2023 |
A paradoxical role for regulatory T cells in the tumor microenvironment of pancreatic cancer T Brouwer, M Ijsselsteijn, J Oosting, D Ruano, M van der Ploeg, F Dijk, ... Cancers 14 (16), 3862, 2022 | 17 | 2022 |