MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency K Clément, H Biebermann, IS Farooqi, L Van der Ploeg, B Wolters, ... Nature medicine 24 (5), 551-555, 2018 | 274 | 2018 |
Structures of active melanocortin-4 receptor–Gs-protein complexes with NDP-α-MSH and setmelanotide NA Heyder, G Kleinau, D Speck, A Schmidt, S Paisdzior, M Szczepek, ... Cell Research 31 (11), 1176-1189, 2021 | 58 | 2021 |
Signal transduction and pathogenic modifications at the melanocortin-4 receptor: A structural perspective N Heyder, G Kleinau, M Szczepek, D Kwiatkowski, D Speck, L Soletto, ... Frontiers in endocrinology 10, 515, 2019 | 35 | 2019 |
Structural complexity and plasticity of signaling regulation at the melanocortin-4 receptor G Kleinau, NA Heyder, YX Tao, P Scheerer International Journal of Molecular Sciences 21 (16), 5728, 2020 | 14 | 2020 |
Binding, thermodynamics, and selectivity of a non-peptide antagonist to the melanocortin-4 receptor N Saleh, G Kleinau, N Heyder, T Clark, PW Hildebrand, P Scheerer Frontiers in Pharmacology 9, 560, 2018 | 11 | 2018 |
Analysis of ligand-and mutation-dependent signaling of the melanocortin 4 receptor (MC4R): an example of the relevance of differential signaling (bias signaling) L Ruck, S Paisdzior, P Scheerer, S Wiegand, G Kleinau, NA Heyder, ... HORMONE RESEARCH IN PAEDIATRICS 96, 36-36, 2023 | | 2023 |
Structural mechanism of calcium-mediated drug binding and G-protein coupling to the melanocortin 4 receptor NA Heyder PQDT-Global, 2022 | | 2022 |