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Jeffrey R. Jacobson, M.D.
Jeffrey R. Jacobson, M.D.
Professor and Senior Associate Head of Medicine, University of Illinois at Chicago
Verified email at uic.edu
Title
Cited by
Cited by
Year
Therapeutic anticoagulation with heparin in noncritically ill patients with Covid-19
ATTACC, ACTIV-4a, and REMAP-CAP Investigators
New England Journal of Medicine 385 (9), 790-802, 2021
10152021
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation
JH Finigan, SM Dudek, PA Singleton, ET Chiang, JR Jacobson, SM Camp, ...
Journal of Biological Chemistry 280 (17), 17286-17293, 2005
4522005
Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury
JR Jacobson, JW Barnard, DN Grigoryev, SF Ma, RM Tuder, JGN Garcia
American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (6 …, 2005
3422005
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase
SM Dudek, JR Jacobson, ET Chiang, KG Birukov, P Wang, X Zhan, ...
Journal of Biological Chemistry 279 (23), 24692-24700, 2004
3332004
Magnitude-dependent regulation of pulmonary endothelial cell barrier function by cyclic stretch
KG Birukov, JR Jacobson, AA Flores, SQ Ye, AA Birukova, AD Verin, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 285 (4 …, 2003
3262003
Prostaglandins PGE2 and PGI2 promote endothelial barrier enhancement via PKA-and Epac1/Rap1-dependent Rac activation
AA Birukova, T Zagranichnaya, P Fu, E Alekseeva, W Chen, JR Jacobson, ...
Experimental cell research 313 (11), 2504-2520, 2007
3062007
Differential effects of sphingosine 1–phosphate receptors on airway and vascular barrier function in the murine lung
S Sammani, L Moreno-Vinasco, T Mirzapoiazova, PA Singleton, ...
American journal of respiratory cell and molecular biology 43 (4), 394-402, 2010
2002010
Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin
JR Jacobson, SM Dudek, KG Birukov, SQ Ye, DN Grigoryev, RE Girgis, ...
American journal of respiratory cell and molecular biology 30 (5), 662-670, 2004
1862004
Sphingosine-1–phosphate, FTY720, and Sphingosine-1–phosphate receptors in the pathobiology of acute lung injury
V Natarajan, SM Dudek, JR Jacobson, L Moreno-Vinasco, LS Huang, ...
American journal of respiratory cell and molecular biology 49 (1), 6-17, 2013
1542013
Essential role of pre–B-cell colony enhancing factor in ventilator-induced lung injury
SB Hong, Y Huang, L Moreno-Vinasco, S Sammani, J Moitra, JW Barnard, ...
American journal of respiratory and critical care medicine 178 (6), 605-617, 2008
1542008
Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition
W Chen, S Pendyala, V Natarajan, JGN Garcia, JR Jacobson
American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (4 …, 2008
1212008
Endothelial cell barrier enhancement by ATP is mediated by the small GTPase Rac and cortactin
JR Jacobson, SM Dudek, PA Singleton, IA Kolosova, AD Verin, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 291 (2 …, 2006
1142006
Enhanced interaction between focal adhesion and adherens junction proteins: involvement in sphingosine 1-phosphate-induced endothelial barrier enhancement
X Sun, Y Shikata, L Wang, K Ohmori, N Watanabe, J Wada, K Shikata, ...
Microvascular research 77 (3), 304-313, 2009
1112009
Sphingosine-1–phosphate receptor–3 is a novel biomarker in acute lung injury
X Sun, PA Singleton, E Letsiou, J Zhao, P Belvitch, S Sammani, ...
American journal of respiratory cell and molecular biology 47 (5), 628-636, 2012
992012
Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation …
PV Usatyuk, P Fu, V Mohan, Y Epshtein, JR Jacobson, ...
Journal of Biological Chemistry 289 (19), 13476-13491, 2014
912014
Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury
AN Rizzo, S Sammani, AE Esquinca, JR Jacobson, JGN Garcia, E Letsiou, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015
882015
Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets
T Wang, C Gross, AA Desai, E Zemskov, X Wu, AN Garcia, JR Jacobson, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (4 …, 2017
812017
Regulation of hyperoxia-induced NADPH oxidase activation in human lung endothelial cells by the actin cytoskeleton and cortactin
PV Usatyuk, LH Romer, D He, NL Parinandi, ME Kleinberg, S Zhan, ...
Journal of Biological Chemistry 282 (32), 23284-23295, 2007
792007
LPS-induced acute lung injury involves NF-κB–mediated downregulation of SOX18
CM Gross, M Kellner, T Wang, Q Lu, X Sun, EA Zemskov, S Noonepalle, ...
American journal of respiratory cell and molecular biology 58 (5), 614-624, 2018
742018
Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression
B Mathew, Y Huang, JR Jacobson, E Berdyshev, LM Gerhold, T Wang, ...
American journal of respiratory cell and molecular biology 44 (3), 415-422, 2011
742011
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