Benoit Deprez
Benoit Deprez
Université de Lille, Institut Pasteur de Lille
Verified email at - Homepage
Cited by
Cited by
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
C Bonner, J Kerr-Conte, V Gmyr, G Queniat, E Moerman, J Thévenet, ...
Nature medicine 21 (5), 512-517, 2015
The bile acid chenodeoxycholic acid increases human brown adipose tissue activity
EPM Broeders, EBM Nascimento, B Havekes, B Brans, KHM Roumans, ...
Cell metabolism 22 (3), 418-426, 2015
Tuberculosis: the drug development pipeline at a glance
B Villemagne, C Crauste, M Flipo, AR Baulard, B Déprez, N Willand
European journal of medicinal chemistry 51, 1-16, 2012
Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a …
D Montaigne, X Marechal, T Modine, A Coisne, S Mouton, G Fayad, ...
The Lancet 391 (10115), 59-69, 2018
Synthetic EthR inhibitors boost antituberculous activity of ethionamide
N Willand, B Dirié, X Carette, P Bifani, A Singhal, M Desroses, F Leroux, ...
Nature medicine 15 (5), 537-544, 2009
Parallel synthesis of 1, 2, 4-oxadiazoles from carboxylic acids using an improved, uronium-based, activation
RF Poulain, AL Tartar, BP Déprez
Tetrahedron Letters 42 (8), 1495-1498, 2001
Efficient propylphosphonic anhydride (® T3P) mediated synthesis of benzothiazoles, benzoxazoles and benzimidazoles
X Wen, J El Bakali, R Deprez-Poulain, B Deprez
Tetrahedron Letters 53 (19), 2440-2443, 2012
Rescue of nonsense mutations by amlexanox in human cells
S Gonzalez-Hilarion, T Beghyn, J Jia, N Debreuck, G Berte, K Mamchaoui, ...
Orphanet journal of rare diseases 7 (1), 1-14, 2012
Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein.
F Martinon, H Gras-Masse, C Boutillon, F Chirat, B Deprez, JG Guillet, ...
The Journal of Immunology 149 (10), 3416-3422, 1992
Versatile Acylation of N-Nucleophiles Using a New Polymer-Supported 1-Hydroxybenzotriazole Derivative
IE Pop, BP Déprez, AL Tartar
The Journal of Organic Chemistry 62 (8), 2594-2603, 1997
Designing focused chemical libraries enriched in protein-protein interaction inhibitors using machine-learning methods
C Reynès, H Host, AC Camproux, G Laconde, F Leroux, A Mazars, ...
PLoS computational biology 6 (3), e1000695, 2010
Orthogonal combinatorial chemical libraries
B Deprez, X Williard, L Bourel, H Coste, F Hyafil, A Tartar
Journal of the American Chemical Society 117 (19), 5405-5406, 1995
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
N Blondiaux, M Moune, M Desroses, R Frita, M Flipo, V Mathys, ...
Science 355 (6330), 1206-1211, 2017
Natural compounds: leads or ideas? Bioinspired molecules for drug discovery
T Beghyn, R Deprez‐Poulain, N Willand, B Folleas, B Deprez
Chemical biology & drug design 72 (1), 3-15, 2008
Hydroxamates: relationships between structure and plasma stability
M Flipo, J Charton, A Hocine, S Dassonneville, B Deprez, ...
Journal of medicinal chemistry 52 (21), 6790-6802, 2009
Ethionamide boosters: synthesis, biological activity, and structure− activity relationships of a series of 1, 2, 4-oxadiazole EthR inhibitors
M Flipo, M Desroses, N Lecat-Guillet, B Dirié, X Carette, F Leroux, ...
Journal of medicinal chemistry 54 (8), 2994-3010, 2011
Monitoring of a three-step solid phase synthesis involving a Heck reaction using magic angle spinning NMR spectroscopy
IE Pop, CF Dhalluin, BP Déprez, PC Melnyk, GM Lippens, AL Tartar
Tetrahedron 52 (37), 12209-12222, 1996
Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1, 2, 4-oxadiazole EthR inhibitors
M Flipo, M Desroses, N Lecat-Guillet, B Villemagne, N Blondiaux, ...
Journal of medicinal chemistry 55 (1), 68-83, 2012
In silico-in vitro screening of protein-protein interactions: towards the next generation of therapeutics
BO Villoutreix, K Bastard, O Sperandio, R Fahraeus, JL Poyet, F Calvo, ...
Current Pharmaceutical Biotechnology 9 (2), 103-122, 2008
Parallel synthesis of polysubstituted tetrahydroquinolines
R Baudelle, P Melnyk, B Déprez, A Tartar
Tetrahedron 54 (16), 4125-4140, 1998
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