GraFit Version 3.0 RJ Leatherbarrow Erithacus Software Ltd., Staines, UK 31, 53-64, 1992 | 684 | 1992 |
Enzfitter: a non-linear regression data analysis program for the IBM PC RJ Leatherbarrow Biosoft, London, 1-99, 1987 | 594 | 1987 |
Grafit version 5 RJ Leatherbarrow Erithacus Software Ltd., Horley, UK, 2001 | 358 | 2001 |
Effector functions of a monoclonal aglycosylated mouse IgG2a: binding and activation of complement component C1 and interaction with human monocyte Fc receptor RJ Leatherbarrow, TW Rademacher, RA Dwek, JM Woof, A Clark, ... Molecular immunology 22 (4), 407-415, 1985 | 307 | 1985 |
Using linear and non-linear regression to fit biochemical data RJ Leatherbarrow Trends in biochemical sciences 15 (12), 455-458, 1990 | 257 | 1990 |
Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering. RJ Leatherbarrow, AR Fersht, G Winter Proceedings of the National Academy of Sciences 82 (23), 7840-7844, 1985 | 248 | 1985 |
Kinetics of protein-protein interactions at the surface of an optical biosensor PR Edwards, A Gill, DV Pollardknight, M Hoare, PE Buckle, PA Lowe, ... Analytical biochemistry 231 (1), 210-217, 1995 | 218 | 1995 |
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach MH Wright, B Clough, MD Rackham, K Rangachari, JA Brannigan, ... Nature chemistry 6 (2), 112-121, 2014 | 213 | 2014 |
GraFit RJ Leatherbarrow Erithacus Software Ltd., Horley, United Kingdom, 2001 | 202 | 2001 |
Structure-activity relationships in engineered proteins: analysis of use of binding energy by linear free energy relationships AR Fersht, RJ Leatherbarrow, TNC Wells Biochemistry 26 (19), 6030-6038, 1987 | 181 | 1987 |
Studies on the mechanism of binding of serum albumins to immobilized cibacron blue F3G A RJ Leatherbarrow, PD Dean Biochemical Journal 189 (1), 27-34, 1980 | 180 | 1980 |
Protein engineering RJ Leatherbarrow, AR Fersht Protein Engineering, Design and Selection 1 (1), 7-16, 1986 | 176 | 1986 |
Enzfitter: a non-linear regression data analysis program for the IBM PC and true compatibles; manuel RJ Leatherbarrow Biosoft, 1987 | 172 | 1987 |
Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides P Thongyoo, N Roqué-Rosell, RJ Leatherbarrow, EW Tate Organic & biomolecular chemistry 6 (8), 1462-1470, 2008 | 171 | 2008 |
N-Myristoyl transferase-mediated protein labelling in vivo WP Heal, SR Wickramasinghe, RJ Leatherbarrow, EW Tate Organic & biomolecular chemistry 6 (13), 2308-2315, 2008 | 169 | 2008 |
Crystal structure of foot-and-mouth disease virus 3C protease: new insights into catalytic mechanism and cleavage specificity JR Birtley, SR Knox, AM Jaulent, P Brick, RJ Leatherbarrow, S Curry Journal of Biological Chemistry 280 (12), 11520-11527, 2005 | 162 | 2005 |
Potent inhibitors of β-tryptase and human leukocyte elastase based on the MCoTI-II scaffold P Thongyoo, C Bonomelli, RJ Leatherbarrow, EW Tate Journal of medicinal chemistry 52 (20), 6197-6200, 2009 | 156 | 2009 |
Quantitative analysis of structure–activity relationships in engineered proteins by linear free-energy relationships AR Fersht, RJ Leatherbarrow, TNC Wells Nature 322 (6076), 284-286, 1986 | 126 | 1986 |
N-myristoyltransferase from Leishmania donovani: structural and functional characterisation of a potential drug target for visceral leishmaniasis JA Brannigan, BA Smith, Z Yu, AM Brzozowski, MR Hodgkinson, A Maroof, ... Journal of molecular biology 396 (4), 985-999, 2010 | 118 | 2010 |
Determination of association rate constants by an optical biosensor using initial rate analysis PR Edwards, RJ Leatherbarrow Analytical biochemistry 246 (1), 1-6, 1997 | 116 | 1997 |