Follow
David M. Sabatini
David M. Sabatini
Institute of Organic Chemistry and Biochemistry of the CAS
Verified email at uochb.cas.cz
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
12818*2021
mTOR signaling in growth control and disease
M Laplante, DM Sabatini
cell 149 (2), 274-293, 2012
92112012
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov, DA Guertin, SM Ali, DM Sabatini
Science 307 (5712), 1098-1101, 2005
82352005
mTOR signaling in growth, metabolism, and disease
RA Saxton, DM Sabatini
Cell 168 (6), 960-976, 2017
69222017
CellProfiler: image analysis software for identifying and quantifying cell phenotypes
AE Carpenter, TR Jones, MR Lamprecht, C Clarke, IH Kang, O Friman, ...
Genome biology 7, 1-11, 2006
54242006
mTOR: from growth signal integration to cancer, diabetes and ageing
R Zoncu, A Efeyan, DM Sabatini
Nature reviews Molecular cell biology 12 (1), 21-35, 2011
46522011
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim, DD Sarbassov, SM Ali, JE King, RR Latek, ...
Cell 110 (2), 163-175, 2002
36692002
Defining the role of mTOR in cancer
DA Guertin, DM Sabatini
Cancer cell 12 (1), 9-22, 2007
34972007
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
DD Sarbassov, SM Ali, DH Kim, DA Guertin, RR Latek, ...
Current biology 14 (14), 1296-1302, 2004
33762004
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
DD Sarbassov, SM Ali, S Sengupta, JH Sheen, PP Hsu, AF Bagley, ...
Molecular cell 22 (2), 159-168, 2006
32442006
Genetic screens in human cells using the CRISPR-Cas9 system
T Wang, JJ Wei, DM Sabatini, ES Lander
Science 343 (6166), 80-84, 2014
32112014
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Y Sancak, TR Peterson, YD Shaul, RA Lindquist, CC Thoreen, ...
Science 320 (5882), 1496-1501, 2008
30462008
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ...
Nature 462 (7269), 108-112, 2009
29802009
Cancer cell metabolism: Warburg and beyond
PP Hsu, DM Sabatini
Cell 134 (5), 703-707, 2008
28332008
mTOR signaling at a glance
M Laplante, DM Sabatini
Journal of cell science 122 (20), 3589-3594, 2009
27902009
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
Y Sancak, L Bar-Peled, R Zoncu, AL Markhard, S Nada, DM Sabatini
Cell 141 (2), 290-303, 2010
26242010
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
CC Thoreen, SA Kang, JW Chang, Q Liu, J Zhang, Y Gao, LJ Reichling, ...
Journal of Biological Chemistry 284 (12), 8023-8032, 2009
20152009
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ...
Cell 124 (6), 1283-1298, 2006
20052006
Growing roles for the mTOR pathway
DD Sarbassov, SM Ali, DM Sabatini
Current opinion in cell biology 17 (6), 596-603, 2005
19932005
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
DM Sabatini, H Erdjument-Bromage, M Lui, P Tempst, SH Snyder
Cell 78 (1), 35-43, 1994
19671994
The system can't perform the operation now. Try again later.
Articles 1–20