Thomas Weimbs, PhD
Thomas Weimbs, PhD
Professor, Department of Molecular, Cellular & Developmental Biology, UCSB
Verified email at - Homepage
Cited by
Cited by
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease
JM Shillingford, NS Murcia, CH Larson, SH Low, R Hedgepeth, N Brown, ...
Proceedings of the National Academy of Sciences 103 (14), 5466-5471, 2006
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease
SH Low, S Vasanth, CH Larson, S Mukherjee, N Sharma, MT Kinter, ...
Developmental cell 10 (1), 57-69, 2006
A conserved domain is present in different families of vesicular fusion proteins: a new superfamily
T Weimbs, SH Low, SJ Chapin, KE Mostov, P Bucher, K Hofmann
Proceedings of the National Academy of Sciences 94 (7), 3046-3051, 1997
Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells.
SH Low, SJ Chapin, T Weimbs, LG Kömüves, MK Bennett, KE Mostov
Molecular biology of the cell 7 (12), 2007-2018, 1996
Proteolipid protein (PLP) of CNS myelin: positions of free, disulfide-bonded, and fatty acid thioester-linked cysteine residues and implications for the membrane topology of PLP
T Weimbs, W Stoffel
Biochemistry 31 (49), 12289-12296, 1992
Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells
G Kreitzer, J Schmoranzer, SH Low, X Li, Y Gan, T Weimbs, SM Simon, ...
Nature cell biology 5 (2), 126-136, 2003
Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1
JM Shillingford, KB Piontek, GG Germino, T Weimbs
Journal of the American Society of Nephrology 21 (3), 489-497, 2010
Polarity proteins control ciliogenesis via kinesin motor interactions
S Fan, TW Hurd, CJ Liu, SW Straight, T Weimbs, EA Hurd, SE Domino, ...
Current biology 14 (16), 1451-1461, 2004
Syntaxin 2 and endobrevin are required for the terminal step of cytokinesis in mammalian cells
SH Low, X Li, M Miura, N Kudo, B Quiñones, T Weimbs
Developmental cell 4 (5), 753-759, 2003
The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells
SH Low, SJ Chapin, C Wimmer, SW Whiteheart, LG Kömüves, KE Mostov, ...
The Journal of cell biology 141 (7), 1503-1513, 1998
A model for structural similarity between different SNARE complexes based on sequence relationships
T Weimbs, K Mostov, SH Low, K Hofmann
Trends in cell biology 8 (7), 260-262, 1998
Polycystin-1 regulates STAT activity by a dual mechanism
JJ Talbot, JM Shillingford, S Vasanth, N Doerr, S Mukherjee, MT Kinter, ...
Proceedings of the National Academy of Sciences 108 (19), 7985-7990, 2011
Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1
T Weimbs
American Journal of Physiology-Renal Physiology 293 (5), F1423-F1432, 2007
Apical targeting in polarized epithelial cells: there's more afloat than rafts
T Weimbs, SH Low, SJ Chapin, KE Mostov
Trends in cell biology 7 (10), 393-399, 1997
Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells
SH Low, PA Roche, HA Anderson, SCD van Ijzendoorn, M Zhang, ...
Journal of Biological Chemistry 273 (6), 3422-3430, 1998
Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases
VE Torres, A Boletta, A Chapman, V Gattone, Y Pei, Q Qian, DP Wallace, ...
Clinical Journal of the American Society of Nephrology 5 (7), 1312-1329, 2010
Folate-conjugated rapamycin slows progression of polycystic kidney disease
JM Shillingford, CP Leamon, IR Vlahov, T Weimbs
Journal of the American Society of Nephrology 23 (10), 1674-1681, 2012
Apical targeting of syntaxin 3 is essential for epithelial cell polarity
N Sharma, SH Low, S Misra, B Pallavi, T Weimbs
Journal of cell biology 173 (6), 937-948, 2006
Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity
SH Low, A Vasanji, J Nanduri, M He, N Sharma, M Koo, J Drazba, ...
Molecular biology of the cell 17 (2), 977-989, 2006
Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells
SCD van IJzendoorn, MJ Tuvim, T Weimbs, BF Dickey, KE Mostov
Developmental cell 2 (2), 219-228, 2002
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