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Sophie Gobeil
Sophie Gobeil
Assistant Professor
Verified email at bcm.ulaval.ca - Homepage
Title
Cited by
Cited by
Year
Controlling the SARS-CoV-2 spike glycoprotein conformation
R Henderson, RJ Edwards, K Mansouri, K Janowska, V Stalls, ...
Nature structural & molecular biology 27 (10), 925-933, 2020
3872020
D614G spike mutation increases SARS CoV-2 susceptibility to neutralization
D Weissman, MG Alameh, T de Silva, P Collini, H Hornsby, R Brown, ...
Cell host & microbe 29 (1), 23-31. e4, 2021
3592021
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, V Stalls, ...
Science 373 (6555), eabi6226, 2021
3462021
D614G mutation alters SARS-CoV-2 spike conformation and enhances protease cleavage at the S1/S2 junction
SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, K Manne, ...
Cell reports 34 (2), 2021
2652021
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies
D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ...
Cell 184 (16), 4203-4219. e32, 2021
2332021
Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses
KO Saunders, E Lee, R Parks, DR Martinez, D Li, H Chen, RJ Edwards, ...
Nature 594 (7864), 553-559, 2021
2232021
Structural diversity of the SARS-CoV-2 Omicron spike
SMC Gobeil, R Henderson, V Stalls, K Janowska, X Huang, A May, ...
Molecular cell 82 (11), 2050-2068. e6, 2022
1442022
Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents
PR Juvvadi, D Fox III, BG Bobay, MJ Hoy, SMC Gobeil, RA Venters, ...
Nature communications 10 (1), 4275, 2019
932019
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice
DR Martinez, A Schäfer, S Gobeil, D Li, G De la Cruz, R Parks, X Lu, ...
Science translational medicine 14 (629), eabj7125, 2021
842021
Cryo-EM structures of SARS-CoV-2 Omicron BA. 2 spike
V Stalls, J Lindenberger, SMC Gobeil, R Henderson, R Parks, M Barr, ...
Cell Reports 39 (13), 2022
742022
Cold sensitivity of the SARS-CoV-2 spike ectodomain
RJ Edwards, K Mansouri, V Stalls, K Manne, B Watts, R Parks, ...
Nature Structural & Molecular Biology 28 (2), 128-131, 2021
692021
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies
WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ...
Cell 184 (11), 2955-2972. e25, 2021
642021
The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates
D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ...
BioRxiv, 2020.12. 31.424729, 2021
592021
Maintenance of native-like protein dynamics may not be required for engineering functional proteins
SMC Gobeil, CM Clouthier, J Park, D Gagné, AM Berghuis, N Doucet, ...
Chemistry & biology 21 (10), 1330-1340, 2014
372014
A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice
DR Martinez, A Schaefer, S Gobeil, D Li, G De la Cruz, R Parks, X Lu, ...
BioRxiv, 2021
332021
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science 373: eabi6226
SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, V Stalls, ...
252021
D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction
SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, K Manne, ...
BioRxiv, 2020.10. 11.335299, 2020
222020
The structural dynamics of engineered β-lactamases vary broadly on three timescales yet sustain native function
SMC Gobeil, MC Ebert, J Park, D Gagné, N Doucet, AM Berghuis, J Pleiss, ...
Scientific Reports 9 (1), 6656, 2019
222019
Chimeric β-lactamases: global conservation of parental function and fast time-scale dynamics with increased slow motions
CM Clouthier, S Morin, SMC Gobeil, N Doucet, J Blanchet, E Nguyen, ...
PloS one 7 (12), e52283, 2012
212012
SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys
KO Saunders, E Lee, R Parks, DR Martinez, D Li, H Chen, RJ Edwards, ...
bioRxiv, 2021.02. 17.431492, 2021
152021
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