Thiago Vargas Seraphim
Thiago Vargas Seraphim
Instituto de Química de São Carlos - Universidade de São Paulo
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A draft of the human septin interactome
M Nakahira, JNA Macedo, TV Seraphim, N Cavalcante, TACB Souza, ...
PLoS One 5 (11), e13799, 2010
Acyldepsipeptide analogs dysregulate human mitochondrial ClpP protease activity and cause apoptotic cell death
KS Wong, MF Mabanglo, TV Seraphim, A Mollica, YQ Mao, K Rizzolo, ...
Cell chemical biology 25 (8), 1017-1030. e9, 2018
Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)
RP Siqueira, ÉAA Barbosa, MD Polêto, GL Righetto, TV Seraphim, ...
PloS one 10 (8), e0134882, 2015
Features of the chaperone cellular network revealed through systematic interaction mapping
K Rizzolo, J Huen, A Kumar, S Phanse, J Vlasblom, Y Kakihara, ...
Cell reports 20 (11), 2735-2748, 2017
Structural and functional studies of Leishmania braziliensis Hsp90
KP Silva, TV Seraphim, JC Borges
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (1), 351-361, 2013
Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy
NN Ferreira, LMB Ferreira, V Miranda-Gonçalves, RM Reis, TV Seraphim, ...
European Journal of Pharmaceutics and Biopharmaceutics 119, 271-282, 2017
Identification of regions involved in substrate binding and dimer stabilization within the central domains of yeast Hsp40 Sis1
JC Borges, TV Seraphim, DZ Mokry, FCL Almeida, DM Cyr, CHI Ramos
PLoS One 7 (12), e50927, 2012
AAA+ proteins
TV Seraphim, WA Houry
Current Biology 30 (6), R251-R257, 2020
Low resolution structural studies indicate that the activator of Hsp90 ATPase 1 (Aha1) of Leishmania braziliensis has an elongated shape which allows its interaction with both …
TV Seraphim, MM Alves, IM Silva, FER Gomes, KP Silva, SMF Murta, ...
PLoS One 8 (6), e66822, 2013
Identification of two p23 co‐chaperone isoforms in Leishmania braziliensis exhibiting similar structures and Hsp90 interaction properties despite divergent stabilities
FAH Batista, GS Almeida, TV Seraphim, KP Silva, SMF Murta, ...
The FEBS journal 282 (2), 388-406, 2015
The interaction networks of Hsp70 and Hsp90 in the Plasmodium and Leishmania parasites
TV Seraphim, CHI Ramos, JC Borges
The molecular chaperones interaction networks in protein folding and …, 2014
A review of multi-domain and flexible molecular chaperones studies by small-angle X-ray scattering
JC Borges, TV Seraphim, PR Dores-Silva, LRS Barbosa
Biophysical Reviews, 1-14, 2016
The C-terminal region of the human p23 chaperone modulates its structure and function
TV Seraphim, LM Gava, DZ Mokry, TC Cagliari, LRS Barbosa, CHI Ramos, ...
Archives of biochemistry and biophysics 565, 57-67, 2015
Plasmodium falciparum R2TP complex: driver of parasite Hsp90 function
TV Seraphim, G Chakafana, A Shonhai, WA Houry
Biophysical Reviews 11 (6), 1007-1015, 2019
ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores
MF Mabanglo, E Leung, S Vahidi, TV Seraphim, BT Eger, S Bryson, ...
Communications biology 2 (1), 410, 2019
Exploiting supramolecular interactions to produce bevacizumab-loaded nanoparticles for potential mucosal delivery
LMB Ferreira, JD Alonso, CP Kiill, NN Ferreira, HH Buzzá, DRM de Godoi, ...
European polymer journal 103, 238-250, 2018
Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes
TV Seraphim, N Nano, YWS Cheung, S Aluksanasuwan, C Colleti, ...
Structure 30 (1), 156-171. e12, 2022
Structural studies of the Hsp70/Hsp90 organizing protein of Plasmodium falciparum and its modulation of Hsp70 and Hsp90 ATPase activities
NSM Silva, DE Bertolino-Reis, PR Dores-Silva, FB Anneta, TV Seraphim, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1868 (1), 140282, 2020
Structural and functional studies of the Leishmania braziliensis SGT co-chaperone indicate that it shares structural features with HIP and can interact with both Hsp90 and …
ALS Coto, TV Seraphim, FAH Batista, PR Dores-Silva, ABF Barranco, ...
International journal of biological macromolecules 118, 693-706, 2018
Sorafenib as an Inhibitor of RUVBL2
N Nano, F Ugwu, TV Seraphim, T Li, G Azer, M Isaac, M Prakesch, ...
Biomolecules 10 (4), 605, 2020
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