Loss of dynamic RNA interaction and aberrant phase separation induced by two distinct types of ALS/FTD-Linked FUS mutations AG Niaki, J Sarkar, X Cai, K Rhine, V Vidaurre, B Guy, M Hurst, JC Lee, ... Molecular Cell 77 (1), 82-94. e4, 2020 | 135 | 2020 |
RNA Droplets K Rhine, V Vidaurre, S Myong Annual Review of Biophysics 49, 247-265, 2020 | 107 | 2020 |
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS K Rhine, MA Makurath, J Liu, S Skanchy, C Lopez, KF Catalan, Y Ma, ... Molecular cell 80 (4), 666-681. e8, 2020 | 74 | 2020 |
Poly (ADP-ribose) drives condensation of FUS via a transient interaction K Rhine, M Dasovich, J Yoniles, M Badiee, S Skanchy, LR Ganser, Y Ge, ... Molecular cell 82 (5), 969-985. e11, 2022 | 43 | 2022 |
Single-molecule and ensemble methods to probe RNP nucleation and condensate properties K Rhine, S Skanchy, S Myong Methods 197, 74-81, 2022 | 12 | 2022 |
A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity CM Fare, K Rhine, A Lam, S Myong, J Shorter Journal of Biological Chemistry 299 (2), 2023 | 8 | 2023 |
Aging RNA granule dynamics in neurodegeneration K Rhine, N Al-Azzam, T Yu, GW Yeo Frontiers in Molecular Biosciences 9, 991641, 2022 | 6 | 2022 |
Regulation of biomolecular condensates by Poly (ADP-ribose) K Rhine, HM Odeh, J Shorter, S Myong Chemical Reviews 123 (14), 9065-9093, 2023 | 4 | 2023 |
Large-scale map of RNA binding protein interactomes across the mRNA life-cycle L Street, K Rothamel, K Brannan, W Jin, B Bokor, K Dong, K Rhine, ... bioRxiv, 2023 | 2 | 2023 |
Single molecule probing of disordered RNA binding proteins K Rhine, S Myong STAR Protocols 3 (1), 101131, 2022 | 1 | 2022 |
Actin filament‐and Wiskott‐Aldrich syndrome protein‐binding sites on fructose‐1, 6‐bisphosphate aldolase are functionally distinct from the active site MH Hui, K Rhine, DR Tolan Cytoskeleton 78 (4), 129-141, 2021 | 1 | 2021 |
Defining the role of DDX6 in regulating FUS condensates G Mekonnen, K Rhine, S Skanchy, S Myong Biophysical Journal 123 (3), 358a, 2024 | | 2024 |
Molecular take on phase separation of FUS S Myong, K Rhine, J Yoniles, M Dasovich, M Badiee, S Skanchy, ... Biophysical Journal 122 (3), 157a, 2023 | | 2023 |
Engineered Nuclear Import Receptor Karyopherin‐β2 Chaperones Aberrant Phase Transitions of Disease‐Associated Cargo CM Fare, VA Korobeynikov, K Rhine, J Yoniles, S Myong, NA Shneider, ... The FASEB Journal 36, 2022 | | 2022 |
HETEROTYPIC INTERACTIONS IN FUS LIQUID-LIQUID PHASE SEPARATION K Rhine Johns Hopkins University, 2022 | | 2022 |
Engineered nuclear import receptor karyopherin-B2 chaperones aberrant phase transitions of disease-associated cargo CM Fare, K Rhine, J Yoniles, S Myong, J Shorter Biophysical Journal 121 (3), 156a, 2022 | | 2022 |
Molecular determinants of Karyopherin-β2 chaperone and disaggregation activity C Fare, K Rhine, A Lam, S Myong, J Shorter bioRxiv, 2022.09. 14.508025, 2022 | | 2022 |
Wild-Type Fus Rescues Altered RNA Binding of ALS-Linked FUS Mutant K Rhine, J Sarkar, AG Niaki, X Cai, G Vidaurre, S Myong Biophysical Journal 116 (3), 213a, 2019 | | 2019 |
ALS/FTLD-Linked Mutations in Glycine Residues of FUS Lead to Immiscibility with Wild-Type FUS K Rhine, MA Makurath, J Liu, C Lopez, KF Catalan, S Skanchy, Y Ma, ... MOLECULAR-CELL-D-20-00585, 0 | | |