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Giulia Caron
Giulia Caron
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Liposome/water lipophilicity: methods, information content, and pharmaceutical applications
GP van Balen, CM Martinet, G Caron, G Bouchard, M Reist, PA Carrupt, ...
Medicinal research reviews 24 (3), 299-324, 2004
1872004
Impact of dynamically exposed polarity on permeability and solubility of chameleonic drugs beyond the rule of 5
M Rossi Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ...
Journal of medicinal chemistry 61 (9), 4189-4202, 2018
1762018
Lipophilicity profiles of ampholytes
A Pagliara, PA Carrupt, G Caron, P Gaillard, B Testa
Chemical reviews 97 (8), 3385-3400, 1997
1751997
Ligand specificity of the genetic variants of human α1-acid glycoprotein: generation of a three-dimensional quantitative structure-activity relationship model for drug binding …
F Hervé, G Caron, JC Duché, P Gaillard, NA Rahman, ...
Molecular Pharmacology 54 (1), 129-138, 1998
1211998
Structure‐Lipophilicity Relationships of Neutral and Protonated β‐Blockers, Part I, Intra‐ and Intermolecular Effects in Isotropic Solvent Systems
G Caron, G Steyaert, A Pagliara, F Reymond, P Crivori, P Gaillard, ...
Helvetica Chimica Acta 82 (8), 1211-1222, 1999
1091999
Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects
G Caron, F Reymond, PA Carrupt, HH Girault, B Testa
Pharmaceutical science & technology today 2 (8), 327-335, 1999
1091999
Molecular Factors Influencing Retention on Immobilized Artificial Membranes (IAM) Compared to Partitioning in Liposomes and n-Octanol
A Taillardat-Bertschinger, CAM Martinet, PA Carrupt, M Reist, G Caron, ...
Pharmaceutical research 19, 729-737, 2002
1082002
Intramolecular hydrogen bonding: An opportunity for improved design in medicinal chemistry
G Caron, J Kihlberg, G Ermondi
Medicinal Research Reviews 39 (5), 1707-1729, 2019
1042019
Lipophilicity behavior of model and medicinal compounds containing a suilfide, sulfoxide, or sulfone moiety
G Caron, P Gaillard, PA Carrupt, B Testa
Helvetica chimica acta 80 (2), 449-462, 1997
1021997
Integrating intramolecular hydrogen bonding (IMHB) considerations in drug discovery using ΔlogP as a tool
M Shalaeva, G Caron, YA Abramov, TN O’Connell, MS Plummer, ...
Journal of medicinal chemistry 56 (12), 4870-4879, 2013
942013
Conformational sampling of macrocyclic drugs in different environments: can we find the relevant conformations?
V Poongavanam, E Danelius, S Peintner, L Alcaraz, G Caron, ...
ACS omega 3 (9), 11742-11757, 2018
842018
Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum (IV) complexes
JA Platts, G Ermondi, G Caron, M Ravera, E Gabano, L Gaviglio, G Pelosi, ...
JBIC Journal of Biological Inorganic Chemistry 16, 361-372, 2011
742011
N‐substituted analogues of S‐nitroso‐N‐acetyl‐D,L‐penicillamine: chemical stability and prolonged nitric oxide mediated vasodilatation in isolated rat femoral …
IL Megson, S Morton, IR Greig, FA Mazzei, RA Field, AR Butler, G Caron, ...
British journal of pharmacology 126 (3), 639-648, 1999
651999
On the complexation of quercetin with methyl-β-cyclodextrin: photostability and antioxidant studies
ME Carlotti, S Sapino, E Ugazio, G Caron
Journal of Inclusion Phenomena and Macrocyclic Chemistry 70, 81-90, 2011
642011
Mechanisms of liposomes/water partitioning of (p-methylbenzyl) alkylamines
R Fruttero, G Caron, E Fornatto, D Boschi, G Ermondi, A Gasco, ...
Pharmaceutical research 15, 1407-1413, 1998
641998
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction
G Ermondi, M Lorenti, G Caron
Journal of medicinal chemistry 47 (16), 3949-3961, 2004
622004
Glycosylated copper (II) ionophores as prodrugs for β-glucosidase activation in targeted cancer therapy
V Oliveri, M Viale, G Caron, C Aiello, R Gangemi, G Vecchio
Dalton Transactions 42 (6), 2023-2034, 2013
612013
Glycosylated copper (II) ionophores as prodrugs for β-glucosidase activation in targeted cancer therapy
V Oliveri, M Viale, G Caron, C Aiello, R Gangemi, G Vecchio
Dalton Transactions 42 (6), 2023-2034, 2013
612013
Flexibility in early drug discovery: focus on the beyond-Rule-of-5 chemical space
G Caron, V Digiesi, S Solaro, G Ermondi
Drug Discovery Today 25 (4), 621-627, 2020
582020
Molecular descriptors for polarity: the need for going beyond polar surface area
G Caron, G Ermondi
Future Medicinal Chemistry 8 (17), 2013-2016, 2016
572016
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