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Kristen E. Pauken
Kristen E. Pauken
The University of Texas MD Anderson Cancer Center
Verified email at mdanderson.org
Title
Cited by
Cited by
Year
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
C Twyman-Saint Victor, AJ Rech, A Maity, R Rengan, KE Pauken, ...
Nature 520 (7547), 373-377, 2015
22962015
The diverse functions of the PD1 inhibitory pathway
AH Sharpe, KE Pauken
Nature Reviews Immunology 18 (3), 153-167, 2018
15912018
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ...
Nature 545 (7652), 60-65, 2017
14742017
Overcoming T cell exhaustion in infection and cancer
KE Pauken, EJ Wherry
Trends in immunology 36 (4), 265-276, 2015
11052015
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
KE Pauken, MA Sammons, PM Odorizzi, S Manne, J Godec, O Khan, ...
Science 354 (6316), 1160-1165, 2016
11022016
Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade
JL Benci, B Xu, Y Qiu, TJ Wu, H Dada, C Twyman-Saint Victor, L Cucolo, ...
Cell 167 (6), 1540-1554. e12, 2016
10202016
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal
BT Fife, KE Pauken, TN Eagar, T Obu, J Wu, Q Tang, M Azuma, ...
Nature immunology 10 (11), 1185-1192, 2009
8622009
Bioenergetic insufficiencies due to metabolic alterations regulated by the inhibitory receptor PD-1 are an early driver of CD8+ T cell exhaustion
B Bengsch, AL Johnson, M Kurachi, PM Odorizzi, KE Pauken, J Attanasio, ...
immunity 45 (2), 358-373, 2016
7032016
Resident memory CD8 T cells trigger protective innate and adaptive immune responses
JM Schenkel, KA Fraser, LK Beura, KE Pauken, V Vezys, D Masopust
Science 346 (6205), 98-101, 2014
7012014
The role of the PD‐1 pathway in autoimmunity and peripheral tolerance
BT Fife, KE Pauken
Annals of the New York Academy of Sciences 1217 (1), 45-59, 2011
4602011
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells
PM Odorizzi, KE Pauken, MA Paley, A Sharpe, EJ Wherry
Journal of Experimental Medicine 212 (7), 1125-1137, 2015
4402015
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
PK Gupta, J Godec, D Wolski, E Adland, K Yates, KE Pauken, C Cosgrove, ...
PLoS pathogens 11 (10), e1005177, 2015
3822015
CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors
LA Kalekar, SE Schmiel, SL Nandiwada, WY Lam, LO Barsness, N Zhang, ...
Nature immunology 17 (3), 304-314, 2016
2472016
Adverse events following cancer immunotherapy: obstacles and opportunities
KE Pauken, M Dougan, NR Rose, AH Lichtman, AH Sharpe
Trends in immunology 40 (6), 511-523, 2019
2232019
IL-15–independent maintenance of tissue-resident and boosted effector memory CD8 T cells
JM Schenkel, KA Fraser, KA Casey, LK Beura, KE Pauken, V Vezys, ...
The Journal of Immunology 196 (9), 3920-3926, 2016
1752016
Not-so-opposite ends of the spectrum: CD8+ T cell dysfunction across chronic infection, cancer and autoimmunity
JL Collier, SA Weiss, KE Pauken, DR Sen, AH Sharpe
Nature immunology 22 (7), 809-819, 2021
1382021
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
JM Schenkel, RH Herbst, D Canner, A Li, M Hillman, SL Shanahan, ...
Immunity 54 (10), 2338-2353. e6, 2021
1312021
TIGIT and CD226: tipping the balance between costimulatory and coinhibitory molecules to augment the cancer immunotherapy toolkit
KE Pauken, EJ Wherry
Cancer cell 26 (6), 785-787, 2014
1212014
Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
KC Osum, AL Burrack, T Martinov, NL Sahli, JS Mitchell, CG Tucker, ...
Scientific reports 8 (1), 8295, 2018
1172018
SnapShot: T cell exhaustion
KE Pauken, EJ Wherry
Cell 163 (4), 1038-1038. e1, 2015
1132015
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