Biomaterials approach to expand and direct differentiation of stem cells C Chai, KW Leong Molecular therapy 15 (3), 467-480, 2007 | 341 | 2007 |
Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells KN Chua, C Chai, PC Lee, YN Tang, S Ramakrishna, KW Leong, HQ Mao Biomaterials 27 (36), 6043-6051, 2006 | 294 | 2006 |
Expansion of engrafting human hematopoietic stem/progenitor cells in three‐dimensional scaffolds with surface‐immobilized fibronectin Q Feng, C Chai, XS Jiang, KW Leong, HQ Mao Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2006 | 195 | 2006 |
A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson’s disease models L Li, CW Zhang, GYJ Chen, B Zhu, C Chai, QH Xu, EK Tan, Q Zhu, KL Lim, ... Nature Communications 5 (1), 3276, 2014 | 188 | 2014 |
RNA interference by nanofiber-based siRNA delivery system H Cao, X Jiang, C Chai, SY Chew Journal of Controlled Release 144 (2), 203-212, 2010 | 160 | 2010 |
Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells KN Chua, C Chai, PC Lee, S Ramakrishna, KW Leong, HQ Mao Experimental hematology 35 (5), 771-781, 2007 | 157 | 2007 |
Co-culture of umbilical cord blood CD34þ cells with human mesenchymal stem cells Y Zhang, C Chai, XS Jiang, SH Teoh, KW Leong Tissue engineering 12 (8), 2161-2170, 2006 | 129 | 2006 |
Genetic insights into sporadic Parkinson's disease pathogenesis C Chai, KL Lim Current Genomics 14 (8), 486-501, 2013 | 125 | 2013 |
Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34+ cells XS Jiang, C Chai, Y Zhang, RX Zhuo, HQ Mao, KW Leong Biomaterials 27 (13), 2723-2732, 2006 | 119 | 2006 |
Parkin Enhances the Expression of Cyclin-dependent Kinase 6 and Negatively Regulates the Proliferation of Breast Cancer Cells*[S] SP Tay, CWS Yeo, C Chai, PJ Chua, HM Tan, AXY Ang, DLH Yip, ... Journal of biological chemistry 285 (38), 29231-29238, 2010 | 117 | 2010 |
A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cells HF Lu, C Chai, TC Lim, MF Leong, JK Lim, S Gao, KL Lim, ACA Wan Biomaterials 35 (9), 2816-2826, 2014 | 90 | 2014 |
Parkin pathway activation mitigates glioma cell proliferation and predicts patient survival CWS Yeo, FSL Ng, C Chai, JMM Tan, GRH Koh, YK Chong, LWH Koh, ... Cancer research 72 (10), 2543-2553, 2012 | 90 | 2012 |
Ff1b is required for the development of steroidogenic component of the zebrafish interrenal organ C Chai, Y Liu, WK Chan Developmental biology 260 (1), 226-244, 2003 | 85 | 2003 |
Developmental expression of a novel Ftz-F1 homologue, ff1b (NR5A4), in the zebrafish Danio rerio C Chai, WK Chan Mechanisms of Development 91 (1-2), 421-426, 2000 | 78 | 2000 |
Static magnetic field stimulation enhances oligodendrocyte differentiation and secretion of neurotrophic factors A Prasad, DBL Teh, A Blasiak, C Chai, Y Wu, PM Gharibani, IH Yang, ... Scientific Reports 7 (1), 6743, 2017 | 69 | 2017 |
A flexi‐PEGDA upconversion implant for wireless brain photodynamic therapy DBL Teh, A Bansal, C Chai, TB Toh, RAJ Tucker, GGL Gammad, Y Yeo, ... Advanced Materials 32 (29), 2001459, 2020 | 67 | 2020 |
Fibronectin immobilized by covalent conjugation or physical adsorption shows different bioactivity on aminated-PET Y Zhang, C Chai, XS Jiang, SH Teoh, KW Leong Materials Science and Engineering: C 27 (2), 213-219, 2007 | 67 | 2007 |
Visualization of intra‐neuronal motor protein transport through upconversion microscopy X Zeng, S Chen, A Weitemier, S Han, A Blasiak, A Prasad, K Zheng, Z Yi, ... Angewandte Chemie 131 (27), 9363-9369, 2019 | 60 | 2019 |
Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination KCM Chew, N Matsuda, K Saisho, GGY Lim, C Chai, HM Tan, K Tanaka, ... PloS one 6 (5), e19720, 2011 | 55 | 2011 |
Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson’s disease ZC Chen, W Zhang, LL Chua, C Chai, R Li, L Lin, Z Cao, DC Angeles, ... Science signaling 10 (488), eaam6790, 2017 | 50 | 2017 |