Bao T. Le
Bao T. Le
Sonstige NamenTri Bao Le, Le BT
Senior Research Scientist
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Antisense oligonucleotides targeting angiogenic factors as potential cancer therapeutics
BT Le, P Raguraman, TR Kosbar, S Fletcher, SD Wilton, RN Veedu
Molecular Therapy-Nucleic Acids 14, 142-157, 2019
Evaluation of anhydrohexitol nucleic acid, cyclohexenyl nucleic acid and d-altritol nucleic acid-modified 2′-O-methyl RNA mixmer antisense oligonucleotides for exon skipping …
BT Le, S Chen, M Abramov, P Herdewijn, RN Veedu
Chemical Communications 52 (92), 13467-13470, 2016
Rational design of short locked nucleic acid-modified 2′-O-methyl antisense oligonucleotides for efficient exon-skipping in vitro
BT Le, AM Adams, S Fletcher, SD Wilton, RN Veedu
Molecular Therapy-Nucleic Acids 9, 155-161, 2017
Systematic evaluation of 2′-Fluoro modified chimeric antisense oligonucleotide-mediated exon skipping in vitro
S Chen, BT Le, M Chakravarthy, TR Kosbar, RN Veedu
Scientific Reports 9 (1), 6078, 2019
Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis
M Chakravarthy, MT Aung-Htut, BT Le, RN Veedu
Scientific reports 7 (1), 1613, 2017
Antisense oligonucleotide modified with serinol nucleic acid (SNA) induces exon skipping in mdx myotubes
BT Le, K Murayama, F Shabanpoor, H Asanuma, RN Veedu
RSC advances 7 (54), 34049-34052, 2017
Construction of a bivalent thrombin binding aptamer and its antidote with improved properties
QW Hughes, BT Le, G Gilmore, RI Baker, RN Veedu
Molecules 22 (10), 1770, 2017
Self-assembling asymmetric peptide-dendrimer micelles – a platform for effective and versatile in vitro nucleic acid delivery
GR Kokil, RN Veedu, BT Le, GA Ramm, HS Parekh
Scientific Reports 8 (1), 4832, 2018
Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide
S Chen, BT Le, K Rahimizadeh, K Shaikh, N Mohal, RN Veedu
Molecules 21 (11), 1582, 2016
Investigation of twisted intercalating nucleic acid (TINA)-modified antisense oligonucleotides for splice modulation by induced exon-skipping in vitro
BT Le, VV Filichev, RN Veedu
RSC advances 6 (97), 95169-95172, 2016
Nucleobase-modified antisense oligonucleotides containing 5-(phenyltriazol)-2′-deoxyuridine nucleotides induce exon-skipping in vitro
BT Le, M Hornum, PK Sharma, P Nielsen, RN Veedu
Rsc Advances 7 (86), 54542-54545, 2017
Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing
BT Le, S Paul, K Jastrzebska, H Langer, MH Caruthers, RN Veedu
Proceedings of the National Academy of Sciences 119 (36), e2207956119, 2022
Novel disulfide-bridged bioresponsive antisense oligonucleotide induces efficient splice modulation in muscle Myotubes in Vitro
BT Le, TR Kosbar, RN Veedu
ACS omega 5 (29), 18035-18039, 2020
Downregulation of vascular endothelial growth factor enhances chemosensitivity by induction of apoptosis in hepatocellular carcinoma cells
DC Chung, HN Son, LT Bao
Cell Journal (Yakhteh) 17 (2), 273, 2015
Evaluation of DNA segments in 2′-modified RNA sequences in designing efficient splice switching antisense oligonucleotides
BT Le, S Agarwal, RN Veedu
RSC advances 11 (23), 14029-14035, 2021
Nanoparticles-assisted aptamer biosensing for the detection of environmental pathogens
K Rahimizadeh, Q ul ain Zahra, S Chen, BT Le, I Ullah, RN Veedu
Environmental research, 117123, 2023
Unlocked nucleic acid modified primer-based enzymatic polymerization assay: towards allele-specific genotype detection of human platelet antigens
BT Le, Q Hughes, S Rakesh, R Baker, PT Jørgensen, J Wengel, ...
RSC advances 8 (57), 32770-32774, 2018
Splice-Modulating Antisense Oligonucleotides as Therapeutics for Inherited Metabolic Diseases
RN Chen, S., Heendeniya, S.N., Le, B.T., Rahimizadeh, K., Rabiee, N., Zahra ...
BioDrugs, 2024
Evaluation of Chemically Modified Nucleic Acid Analogues for Splice Switching Application
BT Le, S Chen, RN Veedu
ACS omega 8 (51), 48650-48661, 2023
Thiomorpholino antisense oligonucleotides for the treatment of PTP1B related diseases
M Caruthers, R Veedu, TB Le
US Patent App. 63/425,161, 2022
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