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Giuseppe Ciaramella
Giuseppe Ciaramella
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Zitiert von
Jahr
Modified mRNA vaccines protect against Zika virus infection
JM Richner, S Himansu, KA Dowd, SL Butler, V Salazar, JM Fox, ...
Cell 168 (6), 1114-1125. e10, 2017
8792017
Preclinical and clinical demonstration of immunogenicity by mRNA vaccines against H10N8 and H7N9 influenza viruses
K Bahl, JJ Senn, O Yuzhakov, A Bulychev, LA Brito, KJ Hassett, ME Laska, ...
Molecular Therapy 25 (6), 1316-1327, 2017
6312017
Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines
KJ Hassett, KE Benenato, E Jacquinet, A Lee, A Woods, O Yuzhakov, ...
Molecular Therapy-Nucleic Acids 15, 1-11, 2019
5782019
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ...
Nature 593 (7859), 429-434, 2021
4812021
Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry
M Westby, C Smith-Burchnell, J Mori, M Lewis, M Mosley, M Stockdale, ...
Journal of virology 81 (5), 2359-2371, 2007
4542007
Directed evolution of adenine base editors with increased activity and therapeutic application
NM Gaudelli, DK Lam, HA Rees, NM Solá-Esteves, LA Barrera, DA Born, ...
Nature biotechnology 38 (7), 892-900, 2020
4202020
mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials
RA Feldman, R Fuhr, I Smolenov, AM Ribeiro, L Panther, M Watson, ...
Vaccine 37 (25), 3326-3334, 2019
3972019
HIV capsid is a tractable target for small molecule therapeutic intervention
WS Blair, C Pickford, SL Irving, DG Brown, M Anderson, R Bazin, J Cao, ...
PLoS pathogens 6 (12), e1001220, 2010
3062010
Efficient targeting and activation of antigen-presenting cells in vivo after modified mRNA vaccine administration in rhesus macaques
F Liang, G Lindgren, A Lin, EA Thompson, S Ols, J Röhss, S John, ...
Molecular Therapy 25 (12), 2635-2647, 2017
2972017
Vaccine mediated protection against Zika virus-induced congenital disease
JM Richner, BW Jagger, C Shan, CR Fontes, KA Dowd, B Cao, ...
Cell 170 (2), 273-283. e12, 2017
2742017
Multi-antigenic human cytomegalovirus mRNA vaccines that elicit potent humoral and cell-mediated immunity
S John, O Yuzhakov, A Woods, J Deterling, K Hassett, CA Shaw, ...
Vaccine 36 (12), 1689-1699, 2018
2112018
A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection
N Kose, JM Fox, G Sapparapu, R Bombardi, RN Tennekoon, AD De Silva, ...
Science immunology 4 (35), eaaw6647, 2019
1882019
Nucleic acid vaccines
G Ciaramella, A Bouchon, EYC Huang
US Patent 10,022,435, 2018
1642018
Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Y Yu, TC Leete, DA Born, L Young, LA Barrera, SJ Lee, HA Rees, ...
Nature Communications 11 (1), 2052, 2020
1632020
Nucleic acid vaccines
G Ciaramella, A Bouchon, EYC Huang
US Patent 9,872,900, 2018
1622018
Modified mRNA-based vaccines elicit robust immune responses and protect guinea pigs from Ebola virus disease
M Meyer, E Huang, O Yuzhakov, P Ramanathan, G Ciaramella, ...
The Journal of infectious diseases 217 (3), 451-455, 2018
1562018
Induction of robust B cell responses after influenza mRNA vaccination is accompanied by circulating hemagglutinin-specific ICOS+ PD-1+ CXCR3+ T follicular helper cells
G Lindgren, S Ols, F Liang, EA Thompson, A Lin, F Hellgren, K Bahl, ...
Frontiers in immunology 8, 1539, 2017
1352017
Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection
AS Espeseth, PJ Cejas, MP Citron, D Wang, DJ DiStefano, C Callahan, ...
npj Vaccines 5 (1), 16, 2020
1242020
Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein.
AD Wardell, W Errington, G Ciaramella, J Merson, MJ McGarvey
Journal of General Virology 80 (3), 701-709, 1999
1201999
Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense
SA Moschos, M Frick, B Taylor, P Turnpenny, H Graves, KG Spink, ...
Molecular Therapy 19 (12), 2163-2168, 2011
1052011
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