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Subha Mukherjee
Subha Mukherjee
Scientific Director, Synthetic Molecule Design and Development, Eli Lilly and Company
Bestätigte E-Mail-Adresse bei illinois.edu
Titel
Zitiert von
Zitiert von
Jahr
Sustainability challenges in peptide synthesis and purification: from R&D to production
A Isidro-Llobet, MN Kenworthy, S Mukherjee, ME Kopach, K Wegner, ...
The Journal of organic chemistry 84 (8), 4615-4628, 2019
3102019
Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis
MA Ortega, DP Cogan, S Mukherjee, N Garg, B Li, GN Thibodeaux, ...
ACS chemical biology 12 (2), 548-557, 2017
822017
Mechanistic studies on the substrate-tolerant lanthipeptide synthetase ProcM
S Mukherjee, WA Van Der Donk
Journal of the American Chemical Society 136 (29), 10450-10459, 2014
702014
Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster
J Gao, KS Ju, X Yu, JE Velásquez, S Mukherjee, J Lee, C Zhao, BS Evans, ...
Angewandte Chemie 126 (5), 1358-1361, 2014
562014
Product formation by the promiscuous lanthipeptide synthetase ProcM is under kinetic control
Y Yu, S Mukherjee, WA Van Der Donk
Journal of the American Chemical Society 137 (15), 5140-5148, 2015
482015
Revisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway
DJ Bougioukou, S Mukherjee, WA Van Der Donk
Proceedings of the National Academy of Sciences 110 (27), 10952-10957, 2013
402013
Bringing Macrolactamization Full Circle: Self-Cleaving Head-to-Tail Macrocyclization of Unprotected Peptides via Mild N-Acyl Urea Activation
CA Arbour, KJ Belavek, R Tariq, S Mukherjee, JK Tom, A Isidro-Llobet, ...
The Journal of Organic Chemistry 84 (2), 1035-1041, 2018
222018
Synthesis and bioactivity of diastereomers of the virulence lanthipeptide cytolysin
S Mukherjee, L Huo, GN Thibodeaux, WA Van Der Donk
Organic letters 18 (23), 6188-6191, 2016
192016
Phosphine-dependent photoinitiation of alkyl thiols under near-UV light facilitates user-friendly peptide desulfurization
NM Venneti, G Samala, RMI Morsy, LG Mendoza, A Isidro-Llobet, JK Tom, ...
Journal of the American Chemical Society 145 (2), 1053-1061, 2023
152023
Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin
DJ Bougioukou, CP Ting, SC Peck, S Mukherjee, WA Van Der Donk
Organic & biomolecular chemistry 17 (4), 822-829, 2019
92019
Development of Two Synthetic Approaches to an APJ Receptor Agonist Containing a Tetra-ortho-Substituted Biaryl Pyridone
MJ Goldfogel, CR Jamison, SA Savage, MW Haley, S Mukherjee, ...
Organic Process Research & Development 26 (3), 624-634, 2021
52021
Chemistry in Water Reproducibility Study: Learnings from a Precompetitive, Multicompany Collaboration
RJ Fox, JD Bailey, JV Obligacion, N Borlinghaus, WM Braje, X Li, ...
Organic Process Research & Development, 2023
22023
Process Development of a Macrocyclic Peptide Inhibitor of PD-L1
S Mukherjee, A Rogers, G Creech, C Hang, A Ramirez, M Dummeldinger, ...
The Journal of Organic Chemistry, 2024
12024
Challenges with the Synthesis of a Macrocyclic Thioether Peptide: From Milligram to Multigram Using Solid Phase Peptide Synthesis (SPPS)
J Kempson, R Zhao, J Pawluczyk, B Wang, H Zhang, X Hou, MP Allen, ...
The Journal of Organic Chemistry, 2024
12024
Process Mass Intensity (PMI): A Holistic Analysis of Current Peptide Manufacturing Processes Informs Sustainability in Peptide Synthesis
I Kekessie, K Wegner, I Martinez, ME Kopach, TD White, JK Tom, ...
The Journal of Organic Chemistry, 2024
12024
Mechanistic and synthetic studies on the prochlorosin and cytolysin families of lanthipeptides
S Mukherjee
University of Illinois at Urbana-Champaign, 2015
12015
Novel synthetic options towards the manufacture of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6-methyl …
N Cuniere, Y Fan, S Kolotuchin, S Mukherjee, EM Simmons, A SINGH, ...
2024
Process toward the manufacture of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6-methyl-1, 4, 7, 8, 9, 10 …
S Mukherjee, WP Gallagher, CR Jamison, S Kolotuchin, A Singh, ...
US Patent App. 18/031,277, 2023
2023
Novel synthetic options towards the manufacture of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6-methyl …
N Cuniere, Y Fan, S Kolutuchin, S Mukherjee, EM Simmons, A Singh, ...
US Patent App. 17/602,059, 2022
2022
New synthetic possibilities towards the production of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6 …
N Cuniere, Y Fan, S Kolotuchin, S Mukherjee, EM Simmons, A Singh, ...
2021
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