Two E3 ubiquitin ligases, SCF‐Skp2 and DDB1‐Cul4, target human Cdt1 for proteolysis H Nishitani, N Sugimoto, V Roukos, Y Nakanishi, M Saijo, C Obuse, ... The EMBO journal 25 (5), 1126-1136, 2006 | 438 | 2006 |
Spatial dynamics of chromosome translocations in living cells V Roukos, TC Voss, CK Schmidt, S Lee, D Wangsa, T Misteli Science 341 (6146), 660-664, 2013 | 319 | 2013 |
The biogenesis of chromosome translocations V Roukos, T Misteli Nature cell biology 16 (4), 293-300, 2014 | 185 | 2014 |
HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types A Zirkel, M Nikolic, K Sofiadis, JP Mallm, CA Brackley, H Gothe, ... Molecular cell 70 (4), 730-744. e6, 2018 | 184 | 2018 |
Cell cycle staging of individual cells by fluorescence microscopy V Roukos, G Pegoraro, TC Voss, T Misteli Nature protocols 10 (2), 334-348, 2015 | 173 | 2015 |
Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations HJ Gothe, BAM Bouwman, EG Gusmao, R Piccinno, G Petrosino, ... Molecular cell 75 (2), 267-283. e12, 2019 | 138 | 2019 |
Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration B Lucic, HC Chen, M Kuzman, E Zorita, J Wegner, V Minneker, W Wang, ... Nature communications 10 (1), 4059, 2019 | 99 | 2019 |
PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression B Dörsam, N Seiwert, S Foersch, S Stroh, G Nagel, D Begaliew, E Diehl, ... Proceedings of the National Academy of Sciences 115 (17), E4061-E4070, 2018 | 86 | 2018 |
R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability T Mosler, F Conte, GMC Longo, I Mikicic, N Kreim, MM Möckel, ... Nature communications 12 (1), 7314, 2021 | 83 | 2021 |
RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis S Zhang, N Übelmesser, N Josipovic, G Forte, JA Slotman, M Chiang, ... Science advances 7 (43), eabg8205, 2021 | 76 | 2021 |
Systematic identification of pathological lamin A interactors TA Dittmer, N Sahni, N Kubben, DE Hill, M Vidal, RC Burgess, V Roukos, ... Molecular biology of the cell 25 (9), 1493-1510, 2014 | 68 | 2014 |
Regulation of Signaling at Regions of Cell-Cell Contact by Endoplasmic Reticulum-Bound Protein-Tyrosine Phosphatase 1B FG Haj, O Sabet, A Kinkhabwala, S Wimmer-Kleikamp, V Roukos, ... PloS one 7 (5), e36633, 2012 | 64 | 2012 |
The cellular etiology of chromosome translocations V Roukos, B Burman, T Misteli Current opinion in cell biology 25 (3), 357-364, 2013 | 50 | 2013 |
Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage V Roukos, A Kinkhabwala, J Colombelli, P Kotsantis, S Taraviras, ... Journal of cell science 124 (3), 422-434, 2011 | 49 | 2011 |
Interconnected contribution of tissue morphogenesis and the nuclear protein NuMA to the DNA damage response PA Vidi, G Chandramouly, M Gray, L Wang, E Liu, JJ Kim, V Roukos, ... Journal of cell science 125 (2), 350-361, 2012 | 48 | 2012 |
Multi-step loading of human minichromosome maintenance proteins in live human cells IE Symeonidou, P Kotsantis, V Roukos, MA Rapsomaniki, HE Grecco, ... Journal of Biological Chemistry 288 (50), 35852-35867, 2013 | 39 | 2013 |
Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma V Roukos, MS Iliou, H Nishitani, M Gentzel, M Wilm, S Taraviras, ... Journal of biological chemistry 282 (13), 9346-9357, 2007 | 33 | 2007 |
Cdt1 Is Differentially Targeted for Degradation by Anticancer Chemotherapeutic Drugs A Stathopoulou, V Roukos, C Petropoulou, P Kotsantis, N Karantzelis, ... PloS one 7 (3), e34621, 2012 | 32 | 2012 |
Genome-wide detection of DNA double-strand breaks by in-suspension BLISS BAM Bouwman, F Agostini, S Garnerone, G Petrosino, HJ Gothe, ... Nature protocols 15 (12), 3894-3941, 2020 | 29 | 2020 |
Generation of cell-based systems to visualize chromosome damage and translocations in living cells V Roukos, RC Burgess, T Misteli Nature protocols 9 (10), 2476-2492, 2014 | 28 | 2014 |