| XBP1 controls diverse cell type-and condition-specific transcriptional regulatory networks D Acosta-Alvear, Y Zhou, A Blais, M Tsikitis, NH Lents, C Arias, ... Molecular cell 27 (1), 53-66, 2007 | 990 | 2007 |
| Pharmacological brake-release of mRNA translation enhances cognitive memory C Sidrauski, D Acosta-Alvear, A Khoutorsky, P Vedantham, BR Hearn, ... elife 2, e00498, 2013 | 633 | 2013 |
| Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis M Lu, DA Lawrence, S Marsters, D Acosta-Alvear, P Kimmig, AS Mendez, ... science 345 (6192), 98-101, 2014 | 590 | 2014 |
| An initial blueprint for myogenic differentiation A Blais, M Tsikitis, D Acosta-Alvear, R Sharan, Y Kluger, BD Dynlacht Genes & development 19 (5), 553-569, 2005 | 527 | 2005 |
| The unfolded protein response: detecting and responding to fluctuations in the protein-folding capacity of the endoplasmic reticulum GE Karagöz, D Acosta-Alvear, P Walter Cold Spring Harbor perspectives in biology 11 (9), a033886, 2019 | 243 | 2019 |
| An unfolded protein-induced conformational switch activates mammalian IRE1 GE Karagöz, D Acosta-Alvear, HT Nguyen, CP Lee, F Chu, P Walter Elife 6, e30700, 2017 | 207 | 2017 |
| Targeting IRE1 with small molecules counteracts progression of atherosclerosis O Tufanli, P Telkoparan Akillilar, D Acosta-Alvear, B Kocaturk, UI Onat, ... Proceedings of the National Academy of Sciences 114 (8), E1395-E1404, 2017 | 196 | 2017 |
| Retinoblastoma tumor suppressor protein–dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit A Blais, CJC van Oevelen, R Margueron, D Acosta-Alvear, BD Dynlacht The Journal of cell biology 179 (7), 1399-1412, 2007 | 147 | 2007 |
| A CHOP-regulated microRNA controls rhodopsin expression S Behrman, D Acosta-Alvear, P Walter Journal of Cell Biology 192 (6), 919-927, 2011 | 135 | 2011 |
| Validation of the Hsp70–Bag3 protein–protein interaction as a potential therapeutic target in cancer X Li, T Colvin, JN Rauch, D Acosta-Alvear, M Kampmann, B Dunyak, ... Molecular cancer therapeutics 14 (3), 642-648, 2015 | 134 | 2015 |
| A scalable, easy-to-deploy protocol for Cas13-based detection of SARS-CoV-2 genetic material JN Rauch, E Valois, SC Solley, F Braig, RS Lach, M Audouard, ... Journal of clinical microbiology 59 (4), 10.1128/jcm. 02402-20, 2021 | 130 | 2021 |
| Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits D Acosta-Alvear, MY Cho, T Wild, TJ Buchholz, AG Lerner, O Simakova, ... elife 4, e08153, 2015 | 102 | 2015 |
| Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells DW Sherbenou, BT Aftab, Y Su, CR Behrens, A Wiita, AC Logan, ... The Journal of clinical investigation 126 (12), 4640-4653, 2016 | 94 | 2016 |
| The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1 D Acosta-Alvear, GE Karagöz, F Fröhlich, H Li, TC Walther, P Walter Elife 7, e43036, 2018 | 93 | 2018 |
| Disruption of IRE1α through its kinase domain attenuates multiple myeloma JM Harnoss, A Le Thomas, A Shemorry, SA Marsters, DA Lawrence, M Lu, ... Proceedings of the National Academy of Sciences 116 (33), 16420-16429, 2019 | 92 | 2019 |
| E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation P Asp, D Acosta-Alvear, M Tsikitis, C Van Oevelen, BD Dynlacht Genes & development 23 (1), 37-53, 2009 | 69 | 2009 |
| Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response E Dufey, JM Bravo-San Pedro, C Eggers, M González-Quiroz, H Urra, ... Nature communications 11 (1), 2401, 2020 | 68 | 2020 |
| Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic AS Mendez, J Alfaro, MA Morales-Soto, AC Dar, E McCullagh, K Gotthardt, ... Elife 4, e05434, 2015 | 64 | 2015 |
| A conformational RNA zipper promotes intron ejection during non‐conventional XBP1 mRNA splicing J Peschek, D Acosta‐Alvear, AS Mendez, P Walter EMBO reports 16 (12), 1688-1698, 2015 | 55 | 2015 |
| The importance of naturally attenuated SARS‐CoV‐2 in the fight against COVID‐19 J Armengaud, A Delaunay‐Moisan, JY Thuret, E Van Anken, ... Environmental microbiology 22 (6), 1997-2000, 2020 | 50 | 2020 |
