| Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse M Garg, Y Nagata, D Kanojia, A Mayakonda, K Yoshida, S Haridas Keloth, ... Blood, The Journal of the American Society of Hematology 126 (22), 2491-2501, 2015 | 219 | 2015 |
| Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma YY Jiang, DC Lin, A Mayakonda, M Hazawa, LW Ding, WW Chien, L Xu, ... Gut 66 (8), 1358-1368, 2017 | 193 | 2017 |
| A novel binding factor facilitates nuclear translocation and transcriptional activation function of the pituitary tumor-transforming gene product W Chien, L Pei Journal of Biological Chemistry 275 (25), 19422-19427, 2000 | 172 | 2000 |
| Cyr61 suppresses growth of human endometrial cancer cells W Chien, T Kumagai, CW Miller, JC Desmond, JM Frank, JW Said, ... Journal of Biological Chemistry 279 (51), 53087-53096, 2004 | 156 | 2004 |
| SAHA, a HDAC inhibitor, has profound anti-growth activity against non-small cell lung cancer cells N Komatsu, N Kawamata, S Takeuchi, D Yin, W Chien, CW Miller, ... Oncology reports 15 (1), 187-191, 2006 | 145 | 2006 |
| Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia V Madan, P Shyamsunder, L Han, A Mayakonda, Y Nagata, ... Leukemia 30 (8), 1672-1681, 2016 | 143 | 2016 |
| Laminin-5γ-2 (LAMC2) is highly expressed in anaplastic thyroid carcinoma and is associated with tumor progression, migration, and invasion by modulating signaling of EGFR M Garg, D Kanojia, R Okamoto, S Jain, V Madan, W Chien, A Sampath, ... The Journal of Clinical Endocrinology & Metabolism 99 (1), E62-E72, 2014 | 125 | 2014 |
| SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway QY Sun, LW Ding, JF Xiao, W Chien, SL Lim, N Hattori, L Goodglick, ... The Journal of pathology 235 (4), 559-570, 2015 | 105 | 2015 |
| Mutational landscape of pediatric acute lymphoblastic leukemia LW Ding, QY Sun, KT Tan, W Chien, AM Thippeswamy, A Eng Juh Yeoh, ... Cancer research 77 (2), 390-400, 2017 | 91 | 2017 |
| Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis W Chien, J O'Kelly, D Lu, A Leiter, J Sohn, D Yin, B Karlan, J Vadgama, ... International journal of oncology 38 (6), 1741-1747, 2011 | 90 | 2011 |
| Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells W Chien, LW Ding, QY Sun, LA Torres-Fernandez, SZ Tan, J Xiao, SL Lim, ... Oncotarget 5 (13), 4881, 2014 | 88 | 2014 |
| Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia H Sun, DC Lin, X Guo, BK Masouleh, S Gery, Q Cao, S Alkan, T Ikezoe, ... Oncotarget 7 (14), 18736, 2016 | 86 | 2016 |
| BCOR regulates myeloid cell proliferation and differentiation Q Cao, MD Gearhart, S Gery, S Shojaee, H Yang, H Sun, DC Lin, JW Bai, ... Leukemia 30 (5), 1155-1165, 2016 | 84 | 2016 |
| Suppression of cell proliferation and signaling transduction by connective tissue growth factor in non–small cell lung cancer cells W Chien, D Yin, D Gui, A Mori, JM Frank, J Said, D Kusuanco, ... Molecular cancer research 4 (8), 591-598, 2006 | 77 | 2006 |
| Ordering of mutations in acute myeloid leukemia with partial tandem duplication of MLL (MLL-PTD) QY Sun, LW Ding, KT Tan, W Chien, A Mayakonda, DC Lin, XY Loh, ... Leukemia 31 (1), 1-10, 2017 | 75 | 2017 |
| SOX7 is down-regulated in lung cancer T Hayano, M Garg, D Yin, M Sudo, N Kawamata, S Shi, W Chien, L Ding, ... Journal of Experimental & Clinical Cancer Research 32, 1-11, 2013 | 74 | 2013 |
| Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer W Chien, QY Sun, KL Lee, LW Ding, P Wuensche, LA Torres-Fernandez, ... Molecular Oncology 9 (4), 889-905, 2015 | 71 | 2015 |
| KPT-330 has antitumour activity against non-small cell lung cancer H Sun, N Hattori, W Chien, Q Sun, M Sudo, L Ding, SL Lim, S Shacham, ... British journal of cancer 111 (2), 281-291, 2014 | 71 | 2014 |
| Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in … W Chien, DH Lee, Y Zheng, P Wuensche, R Alvarez, DL Wen, AM Aribi, ... Molecular carcinogenesis 53 (9), 722-735, 2014 | 65 | 2014 |
| Belinostat and panobinostat (HDACI): in vitro and in vivo studies in thyroid cancer D Chan, Y Zheng, JW Tyner, WJ Chng, WW Chien, S Gery, G Leong, ... Journal of cancer research and clinical oncology 139, 1507-1514, 2013 | 51 | 2013 |
