Pharmacogenetics in breast cancer therapy SH Tan, SC Lee, BC Goh, J Wong Clinical Cancer Research 14 (24), 8027-8041, 2008 | 114 | 2008 |
The landscape of chromothripsis across adult cancer types N Voronina, JKL Wong, D Hübschmann, M Hlevnjak, S Uhrig, CE Heilig, ... Nature communications 11 (1), 2320, 2020 | 106 | 2020 |
Correction of Hirschsprung-associated mutations in human induced pluripotent stem cells via clustered regularly interspaced short palindromic repeats/Cas9, restores neural … FPL Lai, ST Lau, JKL Wong, H Gui, RX Wang, T Zhou, WH Lai, HF Tse, ... Gastroenterology 153 (1), 139-153. e8, 2017 | 83 | 2017 |
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors M Ratnaparkhe, JKL Wong, PC Wei, M Hlevnjak, T Kolb, M Simovic, ... Nature communications 9 (1), 4760, 2018 | 77 | 2018 |
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity BS Hanna, L Llao-Cid, M Iskar, PM Roessner, LC Klett, JKL Wong, Y Paul, ... Immunity 54 (12), 2825-2841. e10, 2021 | 59 | 2021 |
Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma YT Chiu, JKL Wong, SW Choi, KMF Sze, DWH Ho, LK Chan, JMF Lee, ... Journal of hepatology 64 (6), 1256-1264, 2016 | 43 | 2016 |
Pathological Features and BRCA1 Mutation Screening in Premenopausal Breast Cancer Patients J Chang, SG Hilsenbeck, JH Sng, J Wong, GC Ragu Clinical cancer research 7 (6), 1739-1742, 2001 | 38 | 2001 |
Adaptation of an internet-based depression prevention intervention for Chinese adolescents: from “CATCH-IT” to “grasp the opportunity” K Sobowale, AN Zhou, BW Van Voorhees, S Stewart, A Tsang, P Ip, ... International Journal of Adolescent Medicine and Health 25 (2), 127-137, 2013 | 23 | 2013 |
Rare variants and de novo variants in mesial temporal lobe epilepsy with hippocampal sclerosis JKL Wong, H Gui, M Kwok, PW Ng, CHT Lui, L Baum, PC Sham, P Kwan, ... Neurology: Genetics 4 (3), e245, 2018 | 21 | 2018 |
Genetic study of congenital bile-duct dilatation identifies de novo and inherited variants in functionally related genes JKL Wong, D Campbell, ND Ngo, F Yeung, G Cheng, CSM Tang, ... BMC medical genomics 9, 1-10, 2016 | 20 | 2016 |
Chromothripsis in human breast cancer M Bolkestein, JKL Wong, V Thewes, V Körber, M Hlevnjak, S Elgaafary, ... Cancer research 80 (22), 4918-4931, 2020 | 17 | 2020 |
Cancer gene mutations in congenital pulmonary airway malformation patients JS Hsu, R Zhang, F Yeung, CSM Tang, JKL Wong, MT So, H Xia, P Sham, ... ERJ Open Research 5 (1), 2019 | 17 | 2019 |
Association of mutation signature effectuating processes with mutation hotspots in driver genes and non-coding regions JKL Wong, C Aichmüller, M Schulze, M Hlevnjak, S Elgaafary, P Lichter, ... Nature Communications 13 (1), 178, 2022 | 14 | 2022 |
Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism W Liu, JKL Wong, Q He, EHM Wong, CSM Tang, R Zhang, M So, ... BMC medical genetics 16, 1-8, 2015 | 11 | 2015 |
Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability RG Parra, MJ Przybilla, M Simovic, H Susak, M Ratnaparkhe, JKL Wong, ... bioRxiv, 2021.06. 25.449944, 2021 | 9 | 2021 |
A synergistic interaction between HDAC‐and PARP inhibitors in childhood tumors with chromothripsis U Khalid, M Simovic, LA Hammann, M Iskar, JKL Wong, R Kumar, ... International Journal of Cancer 151 (4), 590-606, 2022 | 6 | 2022 |
Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model M Simovic, M Bolkestein, M Moustafa, JKL Wong, V Körber, S Benedetto, ... Neuro-oncology 23 (12), 2028-2041, 2021 | 6 | 2021 |
Evidence for a pre-malignant cell line in a skin biopsy from a patient with Nijmegen breakage syndrome R Habib, H Neitzel, A Ernst, JKL Wong, B Goryluk-Kozakiewicz, A Gerlach, ... Molecular cytogenetics 11, 1-9, 2018 | 5 | 2018 |
A versatile system to introduce clusters of genomic double‐strand breaks in large cell populations T Kolb, U Khalid, M Simović, M Ratnaparkhe, J Wong, A Jauch, ... Genes, Chromosomes and Cancer 60 (5), 303-313, 2021 | 4 | 2021 |
Single-cell omics analyses identify the TIM-3 ligand Galectin-9 as Novel Immunotherapy Target for chronic lymphocytic leukemia L Llaó Cid, JKL Wong, M Wierz, Y Paul, T Roider, I Fernandez Botana, ... Blood 140 (Supplement 1), 1805-1806, 2022 | 2 | 2022 |