Paul Roche
Paul Roche
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Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
PA Roche, P Cresswell
Nature 345 (6276), 615-618, 1990
The ins and outs of MHC class II-mediated antigen processing and presentation
PA Roche, K Furuta
Nature Reviews Immunology 15 (4), 203-216, 2015
Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain
PA Roche, MS Marks, PJ Cresswell
Nature 354 (6352), 392-394, 1991
Identification of a novel syntaxin-and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues
V Ravichandran, A Chawla, PA Roche
Journal of Biological Chemistry 271 (23), 13300-13303, 1996
Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation
HA Anderson, EM Hiltbold, PA Roche
Nature immunology 1 (2), 156-162, 2000
Defective cytotoxic lymphocyte degranulation in syntaxin-11–deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
YT Bryceson, E Rudd, C Zheng, J Edner, D Ma, SM Wood, ...
Blood, The Journal of the American Society of Hematology 110 (6), 1906-1915, 2007
Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules.
PA Roche, P Cresswell
Proceedings of the National Academy of Sciences 88 (8), 3150-3154, 1991
Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization
PA Roche, CL Teletski, E Stang, O Bakke, EO Long
Proceedings of the National Academy of Sciences 90 (18), 8581-8585, 1993
TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation
P Nair-Gupta, A Baccarini, N Tung, F Seyffer, O Florey, Y Huang, ...
Cell 158 (3), 506-521, 2014
T cell‐induced secretion of MHC class II–peptide complexes on B cell exosomes
A Muntasell, AC Berger, PA Roche
The EMBO journal 26 (19), 4263-4272, 2007
A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.
MS Marks, PA Roche, E Van Donselaar, L Woodruff, PJ Peters, ...
The Journal of cell biology 131 (2), 351-369, 1995
Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms
N Puri, PA Roche
Proceedings of the National Academy of Sciences 105 (7), 2580-2585, 2008
High-affinity binding of an influenza hemagglutinin-derived peptide to purified HLA-DR.
PA Roche, P Cresswell
The Journal of Immunology 144 (5), 1849-1856, 1990
HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes
JD Weissman, JA Brown, TK Howcroft, J Hwang, A Chawla, PA Roche, ...
Proceedings of the National Academy of Sciences 95 (20), 11601-11606, 1998
Suppression of antigen presentation by IL-10
SK Mittal, PA Roche
Current opinion in immunology 34, 22-27, 2015
Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis
HF Langer, KJ Chung, VV Orlova, EY Choi, S Kaul, MJ Kruhlak, ...
Blood, The Journal of the American Society of Hematology 116 (22), 4395-4403, 2010
Trafficking of MHC class II molecules in the late secretory pathway
EM Hiltbold, PA Roche
Current opinion in immunology 14 (1), 30-35, 2002
Major histocompatibility complex class II-peptide complexes internalize using a clathrin-and dynamin-independent endocytosis pathway
E Walseng, O Bakke, PA Roche
Journal of Biological Chemistry 283 (21), 14717-14727, 2008
MHC class II-peptide complexes and APC lipid rafts accumulate at the immunological synapse
EM Hiltbold, NJ Poloso, PA Roche
The Journal of Immunology 170 (3), 1329-1338, 2003
A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking
YH Suh, A Terashima, RS Petralia, RJ Wenthold, JTR Isaac, KW Roche, ...
Nature neuroscience 13 (3), 338, 2010
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