Jennifer Nichols
Jennifer Nichols
Bestätigte E-Mail-Adresse bei cam.ac.uk
TitelZitiert vonJahr
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
I Chambers, D Colby, M Robertson, J Nichols, S Lee, S Tweedie, A Smith
Cell 113 (5), 643-655, 2003
35712003
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
J Nichols, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, ...
Cell 95 (3), 379-391, 1998
35111998
The ground state of embryonic stem cell self-renewal
QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ...
Nature 453 (7194), 519, 2008
26542008
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
QL Ying, J Nichols, I Chambers, A Smith
Cell 115 (3), 281-292, 2003
22872003
Changing potency by spontaneous fusion
QL Ying, J Nichols, EP Evans, AG Smith
Nature 416 (6880), 545, 2002
19212002
Nanog safeguards pluripotency and mediates germline development
I Chambers, J Silva, D Colby, J Nichols, B Nijmeijer, M Robertson, ...
Nature 450 (7173), 1230, 2007
14002007
Naive and primed pluripotent states
J Nichols, A Smith
Cell stem cell 4 (6), 487-492, 2009
12422009
Nanog is the gateway to the pluripotent ground state
J Silva, J Nichols, TW Theunissen, G Guo, AL van Oosten, O Barrandon, ...
Cell 138 (4), 722-737, 2009
9112009
Promotion of reprogramming to ground state pluripotency by signal inhibition
J Silva, O Barrandon, J Nichols, J Kawaguchi, TW Theunissen, A Smith
PLoS biology 6 (10), e253, 2008
8052008
Klf4 reverts developmentally programmed restriction of ground state pluripotency
G Guo, J Yang, J Nichols, JS Hall, I Eyres, W Mansfield, A Smith
Development 136 (7), 1063-1069, 2009
6502009
The transcriptional and epigenomic foundations of ground state pluripotency
H Marks, T Kalkan, R Menafra, S Denissov, K Jones, H Hofemeister, ...
Cell 149 (3), 590-604, 2012
6302012
Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells
T Burdon, C Stracey, I Chambers, J Nichols, A Smith
Developmental biology 210 (1), 30-43, 1999
6231999
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
J Nichols, J Silva, M Roode, A Smith
Development 136 (19), 3215-3222, 2009
4902009
Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells
T Kalmar, C Lim, P Hayward, S Munoz-Descalzo, J Nichols, ...
PLoS biology 7 (7), e1000149, 2009
4862009
Resetting transcription factor control circuitry toward ground-state pluripotency in human
Y Takashima, G Guo, R Loos, J Nichols, G Ficz, F Krueger, D Oxley, ...
Cell 158 (6), 1254-1269, 2014
4772014
Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity
J Nichols, EP Evans, AG Smith
Development 110 (4), 1341-1348, 1990
4041990
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
K Kaji, IM Caballero, R MacLeod, J Nichols, VA Wilson, B Hendrich
Nature cell biology 8 (3), 285, 2006
3592006
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression
P Mountford, B Zevnik, A Düwel, J Nichols, M Li, C Dani, M Robertson, ...
Proceedings of the National Academy of Sciences 91 (10), 4303-4307, 1994
3431994
Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal
J Hall, G Guo, J Wray, I Eyres, J Nichols, L Grotewold, S Morfopoulou, ...
Cell stem cell 5 (6), 597-609, 2009
3202009
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling
E Griffith, S Walker, CA Martin, P Vagnarelli, T Stiff, B Vernay, N Al Sanna, ...
Nature genetics 40 (2), 232, 2008
3012008
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