| Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity KK Quy H. Nguyen, Nicholas Pervolarakis, Kerrigan Blake, Dennis Ma, Ryan ... Nature Communications, 2018 | 308 | 2018 |
| Local lung hypoxia determines epithelial fate decisions during alveolar regeneration Y Xi, T Kim, AN Brumwell, IH Driver, Y Wei, V Tan, JR Jackson, J Xu, ... Nature cell biology 19 (8), 904-914, 2017 | 225 | 2017 |
| Recruited monocytes and type 2 immunity promote lung regeneration following pneumonectomy AJ Lechner, IH Driver, J Lee, CM Conroy, A Nagle, RM Locksley, JR Rock Cell stem cell 21 (1), 120-134. e7, 2017 | 212 | 2017 |
| Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells F Hawkins, P Kramer, A Jacob, I Driver, DC Thomas, KB McCauley, ... The Journal of clinical investigation 127 (6), 2277-2294, 2017 | 197 | 2017 |
| A transient niche regulates the specification of Drosophila intestinal stem cells D Mathur, A Bost, I Driver, B Ohlstein Science 327 (5962), 210-213, 2010 | 193 | 2010 |
| Injury-induced BMP signaling negatively regulates Drosophila midgut homeostasis Z Guo, I Driver, B Ohlstein Journal of Cell Biology 201 (6), 945-961, 2013 | 157 | 2013 |
| High-affinity CD25-binding IL-2 mutants potently stimulate persistent T cell growth BM Rao, I Driver, DA Lauffenburger, KD Wittrup Biochemistry 44 (31), 10696-10701, 2005 | 81 | 2005 |
| Persistent pathology in influenza-infected mouse lungs CM Kanegai, Y Xi, ML Donne, JE Gotts, IH Driver, G Amidzic, AJ Lechner, ... American journal of respiratory cell and molecular biology 55 (4), 613-615, 2016 | 70 | 2016 |
| An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis S Wang, K Li, E Pickholz, R Dobie, KP Matchett, NC Henderson, ... Science translational medicine 15 (677), eadd3949, 2023 | 60 | 2023 |
| Interleukin 2 (IL-2) variants engineered for increased IL-2 receptor α-subunit affinity exhibit increased potency arising from a cell surface ligand reservoir effect BM Rao, I Driver, DA Lauffenburger, KD Wittrup Molecular pharmacology 66 (4), 864-869, 2004 | 51 | 2004 |
| LILRB1 blockade enhances bispecific T cell engager antibody–induced tumor cell killing by effector CD8+ T cells A Kim, CJ Han, I Driver, A Olow, AK Sewell, Z Zhang, W Ouyang, JG Egen, ... The Journal of Immunology 203 (4), 1076-1087, 2019 | 35 | 2019 |
| Specification of regional intestinal stem cell identity during Drosophila metamorphosis I Driver, B Ohlstein Development 141 (9), 1848-1856, 2014 | 29 | 2014 |
| Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein DR Lu, H Wu, I Driver, S Ingersoll, S Sohn, S Wang, CM Li, H Phee Life Science Alliance 3 (5), 2020 | 13 | 2020 |
| Increased Affinity of Interleukin-2 Ligand to the Interleukin-2 α-Receptor Leads to Increased Ligand Persistance and Cell Growth I Driver MIT Undergraduate Research Journal 11, 48-52, 2004 | 2 | 2004 |
| A Discovery Platform that Screens Thousands of Gene Therapy Candidates in a Single Animal MB Jensen, C Carrico, I Chandrakumar, I Driver, D Fuentes, A Kuwahara, ... MOLECULAR THERAPY 28 (4), 71-71, 2020 | 1 | 2020 |
| Correction: LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody–Induced Tumor Cell Killing by Effector CD8+ T Cells A Kim, CJ Han, I Driver, A Olow, AK Sewell, Z Zhang, W Ouyang, JG Egen, ... The Journal of Immunology 203 (7), 2023-2024, 2019 | 1 | 2019 |
| AN AUTOCRINE SIGNALING CIRCUIT IN HEPATIC STELLATE CELLS UNDERLIES ADVANCED FIBROSIS IN NON-ALCOHOLIC STEATOHEPATITIS S Wang, K Li, E Pickholz, R Dobie, NC Henderson, C Carrico, I Driver, ... HEPATOLOGY 76, S425-S426, 2022 | | 2022 |
| Gene Therapy for Complex Disease: In Vivo Pooled Screening Predicts Clinical Outcomes In Steatohepatitis A Araki, MB Jensen, C Carrico, L Chio, I Driver, D Fuentes, A Kuwahara, ... MOLECULAR THERAPY 30 (4), 474-475, 2022 | | 2022 |
| A DISCOVERY PLATFORM THAT SCREENS THOUSANDS OF THERAPEUTIC CANDIDATES IN A SINGLE ANIMAL MODEL MB Jensen, C Carrico, L Chio, I Driver, D Fuentes, A Kuwahara, F LePort, ... HEPATOLOGY 74, 1128A-1128A, 2021 | | 2021 |
| FGF19 Gene Therapy Reduces Steatosis but Not Inflammation and Fibrosis in Two Mouse Models of Non-Alcoholic Steatohepatitis MB Jensen, C Carrico, L Chio, I Driver, D Fuentes, A Kuwahara, F LePort, ... MOLECULAR THERAPY 29 (4), 249-249, 2021 | | 2021 |
Jason R. RockGenentech, IncVerified email at gene.com
