Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells HS Martinsson-Ahlzén, V Liberal, B Grünenfelder, SR Chaves, CH Spruck, ... Molecular and cellular biology 28 (18), 5698-5709, 2008 | 140 | 2008 |
Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release C Marques, CSF Oliveira, S Alves, SR Chaves, OP Coutinho, ... Cell death & disease 4 (2), e507, 2013 | 122 | 2013 |
The impact of acetate metabolism on yeast fermentative performance and wine quality: reduction of volatile acidity of grape musts and wines A Vilela-Moura, D Schuller, A Mendes-Faia, RD Silva, SR Chaves, ... Applied microbiology and biotechnology 89 (2), 271-280, 2011 | 120 | 2011 |
Mitochondrial degradation in acetic acid‐induced yeast apoptosis: the role of Pep4 and the ADP/ATP carrier C Pereira, S Chaves, S Alves, B Salin, N Camougrand, S Manon, ... Molecular microbiology 76 (6), 1398-1410, 2010 | 105 | 2010 |
The role of diet-related short-chain fatty acids in colorectal cancer metabolism and survival: prevention and therapeutic implications S Gomes, CSF Oliveira, J Azevedo-Silva, MR Casanova, J Barreto, ... Current medicinal chemistry, 2019 | 92 | 2019 |
Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria CSF Oliveira, H Pereira, S Alves, L Castro, F Baltazar, SR Chaves, ... Cell death & disease 6 (6), e1788, 2015 | 69 | 2015 |
Genome-wide identification of genes involved in the positive and negative regulation of acetic acid-induced programmed cell death in Saccharomyces cerevisiae M Sousa, AM Duarte, TR Fernandes, SR Chaves, A Pacheco, C Leão, ... BMC Genomics 14 (1), 838, 2013 | 62 | 2013 |
Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism A Rego, M Costa, SR Chaves, N Matmati, H Pereira, MJ Sousa, ... PloS one 7 (11), e48571, 2012 | 62 | 2012 |
The yeast model system as a tool towards the understanding of apoptosis regulation by sphingolipids A Rego, D Trindade, SR Chaves, S Manon, V Costa, MJ Sousa, ... FEMS yeast research 14 (1), 160-178, 2014 | 57 | 2014 |
Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy S Alves, L Castro, MS Fernandes, R Francisco, P Castro, M Priault, ... Oncotarget 6 (31), 30787, 2015 | 53 | 2015 |
Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging AD Barbosa, J Graça, V Mendes, SR Chaves, MA Amorim, MV Mendes, ... Mechanisms of ageing and development 133 (5), 317-330, 2012 | 36 | 2012 |
Nuclear import of Spo12p, a protein essential for meiosis SR Chaves, G Blobel Journal of Biological Chemistry 276 (21), 17712-17717, 2001 | 36 | 2001 |
Regulation of cell death induced by acetic acid in yeasts SR Chaves, A Rego, VM Martins, C Santos-Pereira, MJ Sousa, ... Frontiers in Cell and Developmental Biology 9, 1355, 2021 | 34 | 2021 |
Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells V Teixeira, TC Medeiros, R Vilaça, AT Pereira, SR Chaves, M Côrte-Real, ... Cellular signalling 27 (9), 1840-1849, 2015 | 32 | 2015 |
The Emerging Role of the Yeast Torulaspora delbrueckii in Bread and Wine Production: Using Genetic Manipulation to Study Molecular Basis of Physiological Responses A Pacheco, J Santos, S Chaves, J Almeida, C Leão, MJ Sousa Structure and Function of Food Engineering: InTech, 2012 | 30 | 2012 |
Vacuole-mitochondrial cross-talk during apoptosis in yeast: a model for understanding lysosome-mitochondria-mediated apoptosis in mammals. MJ Sousa, F Azevedo, A Pedras, C Marques, OP Coutinho, A Preto, ... Biochemical Society Transactions 39 (5), 1533-1537, 2011 | 28 | 2011 |
Cks1, Cdk1, and the 19S proteasome collaborate to regulate gene induction-dependent nucleosome eviction in yeast S Chaves, C Baskerville, V Yu, SI Reed Molecular and cellular biology 30 (22), 5284-5294, 2010 | 26 | 2010 |
The protective role of yeast Cathepsin D in acetic acid-induced apoptosis depends on ANT (Aac2p) but not on the voltage-dependent channel (Por1p) H Pereira, F Azevedo, A Rego, MJ Sousa, SR Chaves, M Côrte-Real FEBS letters 587 (2), 200-205, 2013 | 25 | 2013 |
Cell wall dynamics modulate acetic acid-induced apoptotic cell death of Saccharomyces cerevisiae A Rego, AM Duarte, F Azevedo, MJ Sousa, M Côrte-Real, SR Chaves Microbial Cell 1 (9), 303-314, 2014 | 24 | 2014 |
N-terminal acetylation modulates Bax targeting to mitochondria S Alves, L Neiri, SR Chaves, S Vieira, D Trindade, S Manon, ... The international journal of biochemistry & cell biology 95, 35-42, 2018 | 22 | 2018 |