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Charlotte Miriam Fare
Charlotte Miriam Fare
Postdoctoral Fellow, Johns Hopkins University School of Medicine
Verified email at jh.edu
Title
Cited by
Cited by
Year
Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains
L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ...
Cell 173 (3), 677-692. e20, 2018
4192018
Loss of dynamic RNA interaction and aberrant phase separation induced by two distinct types of ALS/FTD-Linked FUS mutations
AG Niaki, J Sarkar, X Cai, K Rhine, V Vidaurre, B Guy, M Hurst, JC Lee, ...
Molecular cell 77 (1), 82-94. e4, 2020
1342020
Higher-order organization of biomolecular condensates
CM Fare, A Villani, LE Drake, J Shorter
Open biology 11 (6), 210137, 2021
1022021
Nuclear import receptors directly bind to arginine-rich dipeptide repeat proteins and suppress their pathological interactions
S Hutten, S Usluer, B Bourgeois, F Simonetti, HM Odeh, CM Fare, ...
Cell reports 33 (12), 2020
742020
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS
K Rhine, MA Makurath, J Liu, S Skanchy, C Lopez, KF Catalan, Y Ma, ...
Molecular cell, 2020
742020
Therapeutic dissolution of aberrant phases by nuclear-import receptors
L Guo, CM Fare, J Shorter
Trends in cell biology 29 (4), 308-322, 2019
652019
Poly (ADP-ribose) drives condensation of FUS via a transient interaction
K Rhine, M Dasovich, J Yoniles, M Badiee, S Skanchy, LR Ganser, Y Ge, ...
Molecular cell 82 (5), 969-985. e11, 2022
432022
Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation
D Beijer, HJ Kim, L Guo, K O’Donovan, I Mademan, T Deconinck, ...
JCI insight 6 (14), 2021
402021
Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation
H Shen, A Yanas, MC Owens, C Zhang, C Fritsch, CM Fare, KE Copley, ...
Molecular cell 82 (14), 2588-2603. e9, 2022
292022
(Dis) Solving the problem of aberrant protein states
CM Fare, J Shorter
Disease Models & Mechanisms 14 (5), dmm048983, 2021
222021
Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy
HJ Kim, P Mohassel, S Donkervoort, L Guo, K O’donovan, M Coughlin, ...
Nature communications 13 (1), 2306, 2022
202022
Nuclear-import receptors counter deleterious phase transitions in neurodegenerative disease
HM Odeh, CM Fare, J Shorter
Journal of molecular biology 434 (1), 167220, 2022
142022
A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity
CM Fare, K Rhine, A Lam, S Myong, J Shorter
Journal of Biological Chemistry 299 (2), 2023
92023
Open access: a role for p53 in c9ALS/FTD?
CM Fare, J Shorter
Trends in Genetics 37 (5), 404-406, 2021
22021
Nuclear pore dysfunction and disease: a complex opportunity
CM Fare, JD Rothstein
Nucleus 15 (1), 2314297, 2024
2024
ENGINEERING KAPβ2 TO DISAGGREGATE DISEASE-ASSOCIATED PROTEINS
C Fare
University of Pennsylvania, 2022
2022
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