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Timothy Warwick
Timothy Warwick
Verified email at vrc.uni-frankfurt.de
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A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes
T Warwick, MH Schulz, S Günther, R Gilsbach, A Neme, C Carlberg, ...
Scientific reports 11 (1), 6518, 2021
392021
The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells
B Pflüger-Müller, JA Oo, J Heering, T Warwick, E Proschak, S Günther, ...
Basic Research in Cardiology 115, 1-16, 2020
212020
HIF1α-AS1 is a DNA: DNA: RNA triplex-forming lncRNA interacting with the HUSH complex
MS Leisegang, JK Bains, S Seredinski, JA Oo, NM Krause, CC Kuo, ...
Nature communications 13 (1), 6563, 2022
182022
Computational methods to study DNA: DNA: RNA triplex formation by lncRNAs
T Warwick, RP Brandes, MS Leisegang
Non-coding RNA 9 (1), 10, 2023
112023
The endothelial-enriched lncRNA LINC00607 mediates angiogenic function
F Boos, JA Oo, T Warwick, S Günther, J Izquierdo Ponce, M Lopez, D Rafii, ...
Basic research in cardiology 118 (1), 5, 2023
102023
Nuclear receptor activation shapes spatial genome organization essential for gene expression control: Lessons learned from the vitamin D receptor
T Warwick, MH Schulz, R Gilsbach, RP Brandes, S Seuter
Nucleic acids research 50 (7), 3745-3763, 2022
102022
Reactive oxygen species differentially modulate the metabolic and transcriptomic response of endothelial cells
N Müller, T Warwick, K Noack, PF Malacarne, AJL Cooper, N Weissmann, ...
Antioxidants 11 (2), 434, 2022
102022
DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells
S Seredinski, F Boos, S Günther, JA Oo, T Warwick, JI Ponce, FF Lillich, ...
Molecular Therapy-Nucleic Acids 27, 1023-1035, 2022
92022
ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting
JA Oo, B Irmer, S Günther, T Warwick, K Pálfi, J Izquierdo Ponce, ...
Scientific reports 10 (1), 19079, 2020
92020
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2
JA Oo, K Pálfi, T Warwick, I Wittig, C Prieto-Garcia, V Matkovic, ...
Cell Reports 41 (7), 2022
82022
A universal model of RNA. DNA: DNA triplex formation accurately predicts genome-wide RNA–DNA interactions
T Warwick, S Seredinski, NM Krause, JK Bains, L Althaus, JA Oo, ...
Briefings in bioinformatics 23 (6), bbac445, 2022
72022
The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice
GK Buchmann, C Schürmann, M Spaeth, W Abplanalp, L Tombor, D John, ...
Redox biology 45, 102050, 2021
72021
Nox4 promotes endothelial differentiation through chromatin remodeling
F Hahner, F Moll, T Warwick, DM Hebchen, GK Buchmann, J Epah, ...
Redox biology 55, 102381, 2022
62022
Loss of endothelial cytochrome P450 reductase induces vascular dysfunction in mice
PF Malacarne, C Ratiu, A Gajos-Draus, N Müller, M Lopez, ...
Hypertension 79 (6), 1216-1226, 2022
42022
Epoxyeicosatrienoic acid and prostanoid crosstalk at the receptor and intracellular signaling levels to maintain vascular tone
PF Malacarne, J Bezzenberger, M Lopez, T Warwick, N Müller, ...
International Journal of Molecular Sciences 23 (11), 5939, 2022
32022
Acute injury to the mouse carotid artery provokes a distinct healing response
T Warwick, GK Buchmann, B Pflüger-Müller, M Spaeth, C Schürmann, ...
Frontiers in Physiology 14, 1125864, 2023
12023
Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling
M Lopez, PF Malacarne, DP Ramanujam, T Warwick, N Müller, J Hu, ...
Frontiers in Physiology 13, 1056369, 2022
12022
RNA-DNA triplexes: molecular mechanisms and functional relevance
MS Leisegang, T Warwick, J Stötzel, RP Brandes
Trends in Biochemical Sciences, 2024
2024
Long non-coding RNAs direct the SWI/SNF complex to cell-specific enhancers
JA Oo, T Warwick, K Pálfi, F McNicoll, C Cao, C Prieto-Garcia, Y Zhou, ...
bioRxiv, 2024.03. 21.585172, 2024
2024
The aging-induced long non-coding RNA MIRIAL controls endothelial cell and mitochondrial function
C Kohnle, S Koziarek, T Warwick, K Theodorou, A Fischer, RP Juni, ...
bioRxiv, 2024.02. 28.582649, 2024
2024
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