| Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner TA Mace, Z Ameen, A Collins, S Wojcik, M Mair, GS Young, JR Fuchs, ... Cancer research 73 (10), 3007-3018, 2013 | 434 | 2013 |
| Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells L Lin, B Hutzen, M Zuo, S Ball, S Deangelis, E Foust, B Pandit, MA Ihnat, ... Cancer research 70 (6), 2445-2454, 2010 | 281 | 2010 |
| Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation KA Jurado, H Wang, A Slaughter, L Feng, JJ Kessl, Y Koh, W Wang, ... Proceedings of the National Academy of Sciences 110 (21), 8690-8695, 2013 | 226 | 2013 |
| Reactions of SmI2 with Alkyl Halides and Ketones: Inner-Sphere vs Outer-Sphere Electron Transfer in Reactions of Sm(II) Reductants RS Miller, JM Sealy, M Shabangi, ML Kuhlman, JR Fuchs, RA Flowers Journal of the American Chemical Society 122 (32), 7718-7722, 2000 | 213 | 2000 |
| Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors JJ Kessl, N Jena, Y Koh, H Taskent-Sezgin, A Slaughter, L Feng, ... Journal of Biological Chemistry 287 (20), 16801-16811, 2012 | 212 | 2012 |
| Total synthesis of (±)-perophoramidine JR Fuchs, RL Funk Journal of the American Chemical Society 126 (16), 5068-5069, 2004 | 206 | 2004 |
| Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030 L Lin, Y Liu, H Li, PK Li, J Fuchs, H Shibata, Y Iwabuchi, J Lin British journal of cancer 105 (2), 212-220, 2011 | 180 | 2011 |
| Structure–activity relationship studies of curcumin analogues JR Fuchs, B Pandit, D Bhasin, JP Etter, N Regan, D Abdelhamid, C Li, ... Bioorganic & medicinal chemistry letters 19 (7), 2065-2069, 2009 | 176 | 2009 |
| Modulation of DNA methylation by a sesquiterpene lactone parthenolide Z Liu, S Liu, Z Xie, RE Pavlovicz, J Wu, P Chen, J Aimiuwu, J Pang, ... Journal of Pharmacology and Experimental Therapeutics 329 (2), 505-514, 2009 | 165 | 2009 |
| A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells L Lin, S Deangelis, E Foust, J Fuchs, C Li, PK Li, EB Schwartz, ... Molecular cancer 9, 1-10, 2010 | 153 | 2010 |
| STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells L Lin, J Fuchs, C Li, V Olson, T Bekaii-Saab, J Lin Biochemical and biophysical research communications 416 (3-4), 246-251, 2011 | 149 | 2011 |
| Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species L Pan, JL Woodard, DM Lucas, JR Fuchs, AD Kinghorn Natural product reports 31 (7), 924-939, 2014 | 146 | 2014 |
| The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity MA Bill, JR Fuchs, C Li, J Yui, C Bakan, DM Benson, EB Schwartz, ... Molecular cancer 9, 1-12, 2010 | 145 | 2010 |
| HIV-1 integrase binds the viral RNA genome and is essential during virion morphogenesis JJ Kessl, SB Kutluay, D Townsend, S Rebensburg, A Slaughter, RC Larue, ... Cell 166 (5), 1257-1268. e12, 2016 | 144 | 2016 |
| Indol-2-one intermediates: mechanistic evidence and synthetic utility. Total syntheses of (±)-flustramines A and C JR Fuchs, RL Funk Organic Letters 7 (4), 677-680, 2005 | 142 | 2005 |
| A new class of multimerization selective inhibitors of HIV-1 integrase A Sharma, A Slaughter, N Jena, L Feng, JJ Kessl, HJ Fadel, N Malani, ... PLoS pathogens 10 (5), e1004171, 2014 | 138 | 2014 |
| The effect of cosolvent on the reducing power of SmI2 in tetrahydrofuran M Shabangi, JM Sealy, JR Fuchs, RA Flowers II Tetrahedron letters 39 (25), 4429-4432, 1998 | 135 | 1998 |
| Structural and mechanistic bases for a potent HIV-1 capsid inhibitor SM Bester, G Wei, H Zhao, D Adu-Ampratwum, N Iqbal, VV Courouble, ... Science 370 (6514), 360-364, 2020 | 131 | 2020 |
| Intramolecular Diels− Alder/1, 3-dipolar cycloaddition cascade of 1, 3, 4-oxadiazoles GI Elliott, JR Fuchs, BSJ Blagg, H Ishikawa, H Tao, ZQ Yuan, DL Boger Journal of the American Chemical Society 128 (32), 10589-10595, 2006 | 130 | 2006 |
| Total synthesis of (±)-Lennoxamine and (±)-Aphanorphine by intramolecular electrophilic aromatic substitution reactions of 2-amidoacroleins JR Fuchs, RL Funk Organic Letters 3 (24), 3923-3925, 2001 | 127 | 2001 |
