SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1 M Rebsamen, L Pochini, T Stasyk, MEG De Araújo, M Galluccio, ... Nature 519 (7544), 477-481, 2015 | 707 | 2015 |
Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1 O Groß, AS Yazdi, CJ Thomas, M Masin, LX Heinz, G Guarda, M Quadroni, ... Immunity 36 (3), 388-400, 2012 | 569 | 2012 |
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB M Rebsamen, LX Heinz, E Meylan, MC Michallet, K Schroder, K Hofmann, ... EMBO reports 10 (8), 916-922, 2009 | 406 | 2009 |
SARS-CoV-2 vaccination in rituximab-treated patients: B cells promote humoral immune responses in the presence of T-cell-mediated immunity D Mrak, S Tobudic, M Koblischke, M Graninger, H Radner, D Sieghart, ... Annals of the rheumatic diseases 80 (10), 1345-1350, 2021 | 243 | 2021 |
A conserved circular network of coregulated lipids modulates innate immune responses MS Köberlin, B Snijder, LX Heinz, CL Baumann, A Fauster, GI Vladimer, ... Cell 162 (1), 170-183, 2015 | 207 | 2015 |
LZTR1 is a regulator of RAS ubiquitination and signaling JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ... Science 362 (6419), 1171-1177, 2018 | 191 | 2018 |
NLRC5 deficiency selectively impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells F Staehli, K Ludigs, LX Heinz, Q Seguin-Estevez, I Ferrero, M Braun, ... The Journal of Immunology 188 (8), 3820-3828, 2012 | 185 | 2012 |
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ... Nature 581 (7808), 316-322, 2020 | 171 | 2020 |
Crystal structure of mammalian acid sphingomyelinase A Gorelik, K Illes, LX Heinz, G Superti-Furga, B Nagar Nature communications 7 (1), 1-9, 2016 | 112 | 2016 |
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity LX Heinz, CL Baumann, MS Köberlin, B Snijder, R Gawish, G Shui, ... Cell Reports 11 (12), 1919-1928, 2015 | 103 | 2015 |
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ... Cell host & microbe 23 (6), 766-774. e5, 2018 | 80 | 2018 |
Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration JK Krishnaswamy, A Singh, U Gowthaman, R Wu, P Gorrepati, ... Proceedings of the National Academy of Sciences 112 (10), 3056-3061, 2015 | 76 | 2015 |
Differential involvement of PU. 1 and Id2 downstream of TGF-β1 during Langerhans-cell commitment LX Heinz, B Platzer, PM Reisner, A Jörgl, S Taschner, F Göbel, ... Blood 107 (4), 1445-1453, 2006 | 76 | 2006 |
Functional crosstalk between membrane lipids and TLR biology MS Köberlin, LX Heinz, G Superti-Furga Current Opinion in Cell Biology 39, 28-36, 2016 | 65 | 2016 |
Additional heterologous versus homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination: a … M Bonelli, D Mrak, S Tobudic, D Sieghart, M Koblischke, P Mandl, ... Annals of the rheumatic diseases 81 (5), 687-694, 2022 | 53 | 2022 |
A surface biotinylation strategy for reproducible plasma membrane protein purification and tracking of genetic and drug-induced alterations K Hörmann, A Stukalov, AC Müller, LX Heinz, G Superti-Furga, ... Journal of proteome research 15 (2), 647-658, 2016 | 53 | 2016 |
Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB A Jörgl, B Platzer, S Taschner, LX Heinz, B Höcher, PM Reisner, ... Blood 109 (1), 185-193, 2007 | 45 | 2007 |
Selectivity, efficacy and safety of JAKinibs: New evidence for a still evolving story M Bonelli, A Kerschbaumer, K Kastrati, K Ghoreschi, M Gadina, LX Heinz, ... Annals of the Rheumatic Diseases 83 (2), 139-160, 2024 | 36 | 2024 |
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking A Fauster, M Rebsamen, KL Willmann, A César-Razquin, E Girardi, ... Cell Death & Differentiation 26 (6), 1138-1155, 2019 | 36 | 2019 |
Immunogenicity and safety of a fourth COVID-19 vaccination in rituximab-treated patients: an open-label extension study D Mrak, E Simader, D Sieghart, P Mandl, H Radner, T Perkmann, ... Annals of the Rheumatic Diseases 81 (12), 1750-1756, 2022 | 34 | 2022 |