Emerging evidence for functional peptides encoded by short open reading frames SJ Andrews, JA Rothnagel Nature Reviews Genetics 15 (3), 193-204, 2014 | 649 | 2014 |
Identification of a major keratinocyte cell envelope protein, loricrin T Mehrel, D Hohl, JA Rothnagel, MA Longley, D Bundman, C Cheng, ... Cell 61 (6), 1103-1112, 1990 | 565 | 1990 |
Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis JA Rothnagel, AM Dominey, LD Dempsey, MA Longley, DA Greenhalgh, ... Science 257 (5073), 1128-1130, 1992 | 448 | 1992 |
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice. K Sellheyer, JR Bickenbach, JA Rothnagel, D Bundman, MA Longley, ... Proceedings of the National Academy of Sciences 90 (11), 5237-5241, 1993 | 340 | 1993 |
Mutation of a type II keratin gene (K6a) in pachyonychia congenita PE Bowden, JL Haley, A Kansky, JA Rothnagel, DO Jones, RJ Turner Nature genetics 10 (3), 363-365, 1995 | 293 | 1995 |
Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. AM Dominey, XJ Wang, LE King Jr, LB Nanney, TA Gagne, K Sellheyer, ... Cell growth & differentiation: the molecular biology journal of the American …, 1993 | 205 | 1993 |
5′‐Untranslated regions with multiple upstream AUG codons can support low‐level translation via leaky scanning and reinitiation XQ Wang, JA Rothnagel Nucleic acids research 32 (4), 1382-1391, 2004 | 195 | 2004 |
Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens JA Rothnagel, H Traupe, S Wojcik, M Huber, D Hohl, MR Pittelkow, ... Nature genetics 7 (4), 485-490, 1994 | 181 | 1994 |
Roles of heterogeneous nuclear ribonucleoproteins A and B in cell proliferation Y He, MA Brown, JA Rothnagel, NA Saunders, R Smith Journal of cell science 118 (14), 3173-3183, 2005 | 161 | 2005 |
Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function. S Imakado, JR Bickenbach, DS Bundman, JA Rothnagel, PS Attar, ... Genes & development 9 (3), 317-329, 1995 | 156 | 1995 |
Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v‐Ha‐ras oncogene DA Greenhalgh, JA Rothnagel, MI Quintanilla, CC Orengo, TA Gagne, ... Molecular carcinogenesis 7 (2), 99-110, 1993 | 154 | 1993 |
Trichohyalin, an intermediate filament-associated protein of the hair follicle. JA Rothnagel, GE Rogers The Journal of cell biology 102 (4), 1419-1429, 1986 | 143 | 1986 |
Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development JR Bickenbach, JM Greer, DS Bundman, JA Rothnagel, DK Roop Journal of investigative dermatology 104 (3), 405-410, 1995 | 125 | 1995 |
The gene for mouse epidermal filaggrin precursor. Its partial characterization, expression, and sequence of a repeating filaggrin unit. JA Rothnagel, T Mehrel, WW Idler, DR Roop, PM Steinert Journal of Biological Chemistry 262 (32), 15643-15648, 1987 | 123 | 1987 |
Epidermis: an attractive target tissue for gene therapy DA Greenhalgh, JA Rothnagel, DR Roop Journal of investigative dermatology 103 (5), 63S, 1994 | 119 | 1994 |
The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression D DiSepio, A Jones, MA Longley, D Bundman, JA Rothnagel, DR Roop Journal of Biological Chemistry 270 (18), 10792-10799, 1995 | 117 | 1995 |
Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element. B Lu, JA Rothnagel, MA Longley, SY Tsai, DR Roop Journal of Biological Chemistry 269 (10), 7443-7449, 1994 | 116 | 1994 |
Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides ML Crowe, XQ Wang, JA Rothnagel BMC genomics 7, 1-10, 2006 | 112 | 2006 |
The structure of the gene for mouse filaggrin and a comparison of the repeating units. JA Rothnagel, PM Steinert Journal of Biological Chemistry 265 (4), 1862-1865, 1990 | 97 | 1990 |
The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis JA Rothnagel, T Seki, M Ogo, MA Longley, SM Wojcik, DS Bundman, ... Differentiation 65 (2), 119-130, 1999 | 88 | 1999 |