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Daniel Nichol
Daniel Nichol
Evolutionary Genomics and Modelling, Institute of Cancer Research, UK
Bestätigte E-Mail-Adresse bei icr.ac.uk
Titel
Zitiert von
Zitiert von
Jahr
Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance
D Nichol, P Jeavons, AG Fletcher, RA Bonomo, PK Maini, JL Paul, ...
PLoS computational biology 11 (9), e1004493, 2015
1322015
The 2019 mathematical oncology roadmap
RC Rockne, A Hawkins-Daarud, KR Swanson, JP Sluka, JA Glazier, ...
Physical biology 16 (4), 041005, 2019
1132019
Antibiotic collateral sensitivity is contingent on the repeatability of evolution
D Nichol, J Rutter, C Bryant, AM Hujer, S Lek, MD Adams, P Jeavons, ...
Nature communications 10 (1), 1-10, 2019
1032019
Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer
A Dhawan, D Nichol, F Kinose, ME Abazeed, A Marusyk, EB Haura, ...
Scientific Reports 7 (1), 1-9, 2017
682017
Subclonal reconstruction of tumors by using machine learning and population genetics
G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ...
Nature Genetics 52 (9), 898-907, 2020
512020
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ...
Nature Communications 11 (1), 1-14, 2020
482020
Evolutionary dynamics of residual disease in human glioblastoma
I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ...
Annals of Oncology 30 (3), 456-463, 2019
412019
Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging
D Nichol, M Robertson-Tessi, P Jeavons, ARA Anderson
Genetics 204 (4), 1523-1539, 2016
402016
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking
GD Cresswell, D Nichol, I Spiteri, H Tari, L Zapata, T Heide, CC Maley, ...
Nature Communications 11 (1), 1-12, 2020
342020
The spatiotemporal evolution of lymph node spread in early breast cancer
P Barry, A Vatsiou, I Spiteri, D Nichol, GD Cresswell, A Acar, N Trahearn, ...
Clinical Cancer Research 24 (19), 4763-4770, 2018
292018
Measuring single cell divisions in human tissues from multi-region sequencing data
B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ...
Nature Communications 11 (1), 1-9, 2020
262020
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
B Lupo, F Sassi, M Pinnelli, F Galimi, ER Zanella, V Vurchio, G Migliardi, ...
Science translational medicine 12 (555), eaax8313, 2020
232020
Model genotype–phenotype mappings and the algorithmic structure of evolution
D Nichol, M Robertson-Tessi, ARA Anderson, P Jeavons
Journal of the Royal Society Interface 16 (160), 20190332, 2019
182019
Exploiting evolutionary herding to control drug resistance in cancer
A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ...
BioRxiv, 566950, 2019
92019
Combining radiomics and mathematical modeling to elucidate mechanisms of resistance to immune checkpoint blockade in non-small cell lung cancer
D Saeed-Vafa, R Bravo, JA Dean, A El-Kenawi, NM Père, M Strobl, ...
bioRxiv, 190561, 2017
92017
Model-based tumor subclonal reconstruction
G Caravagna, T Heide, M Williams, L Zapata, D Nichol, K Chkhaidze, ...
bioRxiv, 586560, 2019
82019
The role of memory in non-genetic inheritance and its impact on cancer treatment resistance
T Cassidy, D Nichol, M Robertson-Tessi, M Craig, ARA Anderson
PLoS computational biology 17 (8), e1009348, 2021
52021
A low-cost, open source, self-contained bacterial EVolutionary biorEactor (EVE)
V Gopalakrishnan, NP Krishnan, E McClure, J Pelesko, D Crozier, ...
bioRxiv, 729434, 2020
52020
Measuring single cell divisions in human cancers from multi-region sequencing data
B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ...
bioRxiv, 560243, 2019
42019
It's too soon to pull the plug on antibiotic cycling
D Nichol, RA Bonomo, JG Scott
The Lancet Infectious Diseases 18 (5), 493, 2018
32018
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