| The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion C Hundhausen, D Misztela, TA Berkhout, N Broadway, P Saftig, K Reiss, ... Blood 102 (4), 1186-1195, 2003 | 796 | 2003 |
| The transmembrane CXC-chemokine ligand 16 is induced by IFN-γ and TNF-α and shed by the activity of the disintegrin-like metalloproteinase ADAM10 S Abel, C Hundhausen, R Mentlein, A Schulte, TA Berkhout, N Broadway, ... The Journal of Immunology 172 (10), 6362-6372, 2004 | 515 | 2004 |
| Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE) V Matthews, B Schuster, S Schutze, I Bussmeyer, A Ludwig, ... Journal of biological chemistry 278 (40), 38829-38839, 2003 | 502 | 2003 |
| Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell … A Ludwig, C Hundhausen, MH Lambert, N Broadway, RC Andrews, ... Combinatorial chemistry & high throughput screening 8 (2), 161-171, 2005 | 414 | 2005 |
| Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis U Laggner, P Di Meglio, GK Perera, C Hundhausen, KE Lacy, N Ali, ... The Journal of Immunology 187 (5), 2783-2793, 2011 | 376 | 2011 |
| Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes C Hundhausen, A Schulte, B Schulz, MG Andrzejewski, N Schwarz, ... The Journal of Immunology 178 (12), 8064-8072, 2007 | 214 | 2007 |
| Progress in understanding the immunopathogenesis of psoriasis RKH Mak, C Hundhausen, FO Nestle Actas dermo-sifiliograficas 100, 2-13, 2009 | 182 | 2009 |
| Enhanced expression and shedding of the transmembrane chemokine CXCL16 by reactive astrocytes and glioma cells A Ludwig, A Schulte, C Schnack, C Hundhausen, K Reiss, N Brodway, ... Journal of neurochemistry 93 (5), 1293-1303, 2005 | 152 | 2005 |
| The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity JA Gorman, C Hundhausen, JS Errett, AE Stone, EJ Allenspach, Y Ge, ... Nature immunology 18 (7), 744-752, 2017 | 120 | 2017 |
| Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression C Hundhausen, A Roth, E Whalen, J Chen, A Schneider, SA Long, S Wei, ... Science translational medicine 8 (356), 356ra119-356ra119, 2016 | 106 | 2016 |
| Sequential processing of the transmembrane chemokines CX3CL1 and CXCL16 by α-and γ-secretases A Schulte, B Schulz, MG Andrzejewski, C Hundhausen, S Mletzko, ... Biochemical and biophysical research communications 358 (1), 233-240, 2007 | 105 | 2007 |
| Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin F Scholz, A Schulte, F Adamski, C Hundhausen, J Mittag, A Schwarz, ... Journal of Investigative Dermatology 127 (6), 1444-1455, 2007 | 96 | 2007 |
| A systems model for immune cell interactions unravels the mechanism of inflammation in human skin NV Valeyev, C Hundhausen, Y Umezawa, NV Kotov, G Williams, A Clop, ... PLoS computational biology 6 (12), e1001024, 2010 | 76 | 2010 |
| An In-Depth Characterization of the Major Psoriasis Susceptibility Locus Identifies Candidate Susceptibility Alleles within an HLA-C Enhancer Element A Clop, A Bertoni, SL Spain, MA Simpson, V Pullabhatla, R Tonda, ... PloS one 8 (8), e71690, 2013 | 60 | 2013 |
| Abatacept targets T follicular helper and regulatory T cells, disrupting molecular pathways that regulate their proliferation and maintenance S Glatigny, B Höllbacher, SJ Motley, C Tan, C Hundhausen, JH Buckner, ... The Journal of Immunology 202 (5), 1373-1382, 2019 | 51 | 2019 |
| Integrative biology approach identifies cytokine targeting strategies for psoriasis GK Perera, C Ainali, E Semenova, C Hundhausen, G Barinaga, D Kassen, ... Science translational medicine 6 (223), 223ra22-223ra22, 2014 | 44 | 2014 |
| The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets JA Gorman, C Hundhausen, M Kinsman, T Arkatkar, EJ Allenspach, ... Frontiers in immunology 10, 44, 2019 | 34 | 2019 |
| Allele-specific cytokine responses at the HLA-C locus: implications for psoriasis C Hundhausen, A Bertoni, RK Mak, E Botti, P Di Meglio, A Clop, ... Journal of investigative dermatology 132 (3), 635-641, 2012 | 34 | 2012 |
| Endothelial hyaluronan synthase 3 augments postischemic arteriogenesis through CD44/eNOS signaling R Schneckmann, T Suvorava, C Hundhausen, D Schuler, C Lorenz, ... Arteriosclerosis, thrombosis, and vascular biology 41 (10), 2551-2562, 2021 | 7 | 2021 |
| Endothelial hyaluronan synthase 3 aggravates acute colitis in an experimental model of inflammatory bowel disease C Hundhausen, R Schneckmann, Y Ostendorf, J Rimpler, A von Glinski, ... Matrix Biology 102, 20-36, 2021 | 6 | 2021 |
Stefan Rose-JohnUniversity of KielBestätigte E-Mail-Adresse bei biochem.uni-kiel.de
