| Cytoplasmic chromatin triggers inflammation in senescence and cancer Z Dou, K Ghosh, MG Vizioli, J Zhu, P Sen, KJ Wangensteen, J Simithy, ... Nature 550 (7676), 402-406, 2017 | 1027 | 2017 |
| Targeting CDK9 reactivates epigenetically silenced genes in cancer H Zhang, S Pandey, M Travers, H Sun, G Morton, J Madzo, W Chung, ... Cell 175 (5), 1244-1258. e26, 2018 | 202 | 2018 |
| Characterization of histone acylations links chromatin modifications with metabolism J Simithy, S Sidoli, ZF Yuan, M Coradin, NV Bhanu, DM Marchione, ... Nature communications 8 (1), 1141, 2017 | 182 | 2017 |
| EpiProfile 2.0: a computational platform for processing epi-proteomics mass spectrometry data ZF Yuan, S Sidoli, DM Marchione, J Simithy, KA Janssen, MR Szurgot, ... Journal of proteome research 17 (7), 2533-2541, 2018 | 136 | 2018 |
| Low resolution data-independent acquisition in an LTQ-Orbitrap allows for simplified and fully untargeted analysis of histone modifications S Sidoli, J Simithy, KR Karch, K Kulej, BA Garcia Analytical chemistry 87 (22), 11448-11454, 2015 | 58 | 2015 |
| Recognition of histone H3K14 acylation by MORF BJ Klein, J Simithy, X Wang, JW Ahn, FH Andrews, Y Zhang, J Côté, X Shi, ... Structure 25 (4), 650-654. e2, 2017 | 52 | 2017 |
| Identification of shikimate kinase inhibitors among anti-Mycobacterium tuberculosis compounds by LC-MS J Simithy, N Reeve, JV Hobrath, RC Reynolds, AI Calderón Tuberculosis 94 (2), 152-158, 2014 | 47 | 2014 |
| Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials S Gordon, J Simithy, DC Goodwin, AI Calderón Perspectives in medicinal chemistry 7, PMC. S13212, 2015 | 37 | 2015 |
| Slow-Binding Inhibition of Mycobacterium tuberculosis Shikimate Kinase by Manzamine Alkaloids J Simithy, NR Fuanta, M Alturki, JV Hobrath, AE Wahba, I Pina, J Rath, ... Biochemistry 57 (32), 4923-4933, 2018 | 32 | 2018 |
| Integrating proteomics and targeted metabolomics to understand global changes in histone modifications J Simithy, S Sidoli, BA Garcia Proteomics 18 (18), 1700309, 2018 | 26 | 2018 |
| Lycopodiaceae from Panama: a new source of acetylcholinesterase inhibitors AI Calderón, J Simithy-Williams, R Sanchez, A Espinosa, I Valdespino, ... Natural Product Research 27 (4-5), 500-505, 2013 | 26 | 2013 |
| Antimalarial natural products drug discovery in Panama AI Calderón, J Simithy-Williams, MP Gupta Pharmaceutical biology 50 (1), 61-71, 2012 | 21 | 2012 |
| Triterpenes from Warszewiczia coccinea (Rubiaceae) as Inhibitors of Acetylcholinesterase AI Calderón, J Simithy, G Quaggio, A Espinosa, JL López-Pérez, ... Natural Product Communications 4 (10), 1934578X0900401002, 2009 | 15 | 2009 |
| Mechanism of irreversible inhibition of Mycobacterium tuberculosis shikimate kinase by ilimaquinone J Simithy, NR Fuanta, JV Hobrath, A Kochanowska-Karamyan, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (5-6), 731-739, 2018 | 14 | 2018 |
| Development of an ESI-LC-MS-Based Assay for Kinetic Evaluation of Mycobacterium tuberculosis Shikimate Kinase Activity and Inhibition J Simithy, G Gill, Y Wang, DC Goodwin, AI Calderon Analytical chemistry 87 (4), 2129-2136, 2015 | 14 | 2015 |
| LC-MS-Based Quality Assessment of a Traditional Chinese Medicine YANG XIN Formulation AJ Almalki, A Zaher, J Simithy, WJ Keller, M Tripp, AI Calderón Planta Medica, 1208-1216, 2016 | 3 | 2016 |
| Development of a functional assay to detect inhibitors of Plasmodium falciparum glutathione reductase utilizing liquid chromatography–mass spectrometry L Burkard, A Scheuermann, J Simithy, AI Calderón Biomedical Chromatography 30 (4), 543-547, 2016 | 3 | 2016 |
| P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS P Lund, S Smith, J Simithy, L Chau, E Friedman, Y Saiman, L Gates, ... Gastroenterology 158 (3), S67, 2020 | | 2020 |
| Imparting intrinsic flourescence as an approach towards rapid inhibitor screening and mechanistic evaluation of tuberculosis shikimate kinase R Fuanta, J Simithy, T Childers, A Calderon, D Goodwin ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
| High resolution mass spectrometry based identification and quantification of chemical markers in a TCM formulation AI Calderón, AJ Almalki, AM Zaher, J Simithy, WJ Keller, M Tripp Planta Medica 81 (11), PA3, 2015 | | 2015 |
Ben GarciaAssociate Professor, University of Pennsylvania School of MedicineBestätigte E-Mail-Adresse bei mail.med.upenn.edu
