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Year
Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers
LJ Cobb, C Lee, J Xiao, K Yen, RG Wong, HK Nakamura, HH Mehta, ...
Aging (Albany NY) 8 (4), 796, 2016
2342016
Mitochondrially derived peptides as novel regulators of metabolism
SJ Kim, J Xiao, J Wan, P Cohen, K Yen
The Journal of Physiology, doi:10.1113/JP274472, 2017
1702017
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus
SJ Kim, N Guerrero, G Wassef, J Xiao, HH Mehta, P Cohen, K Yen
Oncotarget 7 (30), 46899, 2016
922016
Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression
CV Breton, AY Song, J Xiao, SJ Kim, HH Mehta, J Wan, K Yen, C Sioutas, ...
Mitochondrion 46, 22-29, 2019
842019
Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans
K Yen, J Wan, HH Mehta, B Miller, A Christensen, ME Levine, ...
Scientific reports 8 (1), 14212, 2018
812018
Nuclear-encoded lncRNA MALAT1 epigenetically controls metabolic reprogramming in HCC cells through the mitophagy pathway
Y Zhao, L Zhou, H Li, T Sun, X Wen, X Li, Y Meng, Y Li, M Liu, S Liu, ...
Molecular Therapy-Nucleic Acids 23, 264-276, 2021
702021
The mitochondrial-derived peptides, HumaninS14G and small Humanin-like peptide 2, exhibit chaperone-like activity
AK Okada, K Teranishi, F Lobo, JM Isas, J Xiao, K Yen, P Cohen, ...
Scientific reports 7 (1), 7802, 2017
542017
The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity
SJ Kim, B Miller, HH Mehta, J Xiao, J Wan, TE Arpawong, K Yen, P Cohen
Physiological reports 7 (13), e14171, 2019
512019
Humanin: functional interfaces with IGF-I
J Xiao, SJ Kim, P Cohen, K Yen
Growth hormone & IGF research 29, 21-27, 2016
492016
Mitochondrial DNA hypomethylation is a biomarker associated with induced senescence in human fetal heart mesenchymal stem cells
D Yu, Z Du, L Pian, T Li, X Wen, W Li, SJ Kim, J Xiao, P Cohen, J Cui, ...
Stem cells international 2017, 2017
452017
A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c
H Zempo, SJ Kim, N Fuku, Y Nishida, Y Higaki, J Wan, K Yen, B Miller, ...
Aging (Albany NY) 13 (2), 1692, 2021
392021
Metabolomic profile of diet-induced obesity mice in response to humanin and small humanin-like peptide 2 treatment
HH Mehta, J Xiao, R Ramirez, B Miller, SJ Kim, P Cohen, K Yen
Metabolomics 15, 1-12, 2019
392019
Low circulating levels of the mitochondrial-peptide hormone SHLP2: novel biomarker for prostate cancer risk
J Xiao, L Howard, J Wan, E Wiggins, A Vidal, P Cohen, SJ Freedland
Oncotarget 8 (55), 94900, 2017
382017
The potent humanin analogue (HNG) protects germ cells and leucocytes while enhancing chemotherapy-induced suppression of cancer metastases in male mice
YH Lue, R Swerdloff, J Wan, J Xiao, S French, V Atienza, V Canela, ...
Endocrinology 156 (12), 4511-4521, 2015
362015
Mitochondrial biology and prostate cancer ethnic disparity
J Xiao, P Cohen, MC Stern, F Odedina, J Carpten, R Reams
Carcinogenesis 39 (11), 1311-1319, 2018
352018
Subcellular fractionation for ERK activation upon mitochondrial-derived peptide treatment
SJ Kim, J Xiao, P Cohen, K Yen
JoVE (Journal of Visualized Experiments), e56496, 2017
62017
The regulation, roles, and mechanism of action of mitochondrial-derived-peptides (MDPs) in aging
J Xiao
University of Southern California, 2018
12018
Hormone MOTS-c improves metabolic dysfunction in obese mice
SJ Kim, B Miller, HH Mehta, J Xiao, J Wan, TE Arpawong, K Yen, P Cohen
2019
Chaperone-like Activity of Mitochondrially-Derived Peptides Captures Diabetic Amyloid Seeds
AK Okada, K Teranishi, F Lobo, J Xiao, HH Mehta, J Mario, KY Isas, ...
Enhancing and Inhibiting Diabetic Amyloid Misfolding, 108, 2018
2018
OR2-2: The mitochondrial peptide humanin has fasting mimetic activity leading to suppression of circulating IGF-I and increases in IGFBP-1 levels
J Xiao, J Wan, H Mehta, YH Lue, Y Jia, R Swerdloff, C Wang, P Cohen
Growth Hormone & IGF Research, S7-S8, 2014
2014
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