| Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain OK Melemedjian, MN Asiedu, DV Tillu, R Sanoja, J Yan, A Lark, ... Molecular pain 7, 1744-8069-7-70, 2011 | 228 | 2011 |
| IL-6-and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex OK Melemedjian, MN Asiedu, DV Tillu, KA Peebles, J Yan, N Ertz, ... Journal of Neuroscience 30 (45), 15113-15123, 2010 | 221 | 2010 |
| Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain DV Tillu, OK Melemedjian, MN Asiedu, N Qu, M De Felice, G Dussor, ... Molecular Pain 8, 1744-8069-8-5, 2012 | 188 | 2012 |
| Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization MN Asiedu, DV Tillu, OK Melemedjian, A Shy, R Sanoja, B Bodell, ... Journal of Neuroscience 31 (18), 6646-6653, 2011 | 153 | 2011 |
| Descending facilitatory pathways from the RVM initiate and maintain bilateral hyperalgesia after muscle insult DV Tillu, GF Gebhart, KA Sluka Pain 136 (3), 331-339, 2008 | 132 | 2008 |
| BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state OK Melemedjian, DV Tillu, MN Asiedu, EK Mandell, JK Moy, VM Blute, ... Molecular pain 9, 1744-8069-9-12, 2013 | 100 | 2013 |
| Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity OK Melemedjian, DV Tillu, JK Moy, MN Asiedu, EK Mandell, S Ghosh, ... Molecular pain 10, 1744-8069-10-45, 2014 | 99 | 2014 |
| Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism JYV Kim, DV Tillu, TL Quinn, GL Mejia, A Shy, MNK Asiedu, E Murad, ... Journal of Neuroscience 35 (16), 6307-6317, 2015 | 82 | 2015 |
| Protease-activated receptor 2 activation is sufficient to induce the transition to a chronic pain state DV Tillu, SN Hassler, CC Burgos-Vega, TL Quinn, RE Sorge, G Dussor, ... Pain 156 (5), 859-867, 2015 | 73 | 2015 |
| Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain K Hanamura, HR Washburn, SI Sheffler-Collins, NL Xia, N Henderson, ... PLoS biology 15 (7), e2002457, 2017 | 62 | 2017 |
| Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice MD Burton, DV Tillu, K Mazhar, GL Mejia, MN Asiedu, K Inyang, T Hughes, ... Neuroscience 359, 119-129, 2017 | 55 | 2017 |
| The novel PAR2 ligand C391 blocks multiple PAR2 signalling pathways in vitro and in vivo S Boitano, J Hoffman, AN Flynn, MN Asiedu, DV Tillu, Z Zhang, ... British journal of pharmacology 172 (18), 4535-4545, 2015 | 52 | 2015 |
| The protease-activated receptor-2-specific agonists 2-aminothiazol-4-yl-LIGRL-NH2 and 6-aminonicotinyl-LIGRL-NH2 stimulate multiple signaling pathways to induce physiological … AN Flynn, DV Tillu, MN Asiedu, J Hoffman, J Vagner, TJ Price, S Boitano Journal of Biological Chemistry 286 (21), 19076-19088, 2011 | 38 | 2011 |
| Temporal and sex differences in the role of BDNF/TrkB signaling in hyperalgesic priming in mice and rats JK Moy, T Szabo-Pardi, DV Tillu, S Megat, G Pradhan, M Kume, ... Neurobiology of Pain 5, 100024, 2019 | 37 | 2019 |
| Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering AN Flynn, J Hoffman, DV Tillu, CL Sherwood, Z Zhang, R Patek, ... The FASEB Journal 27 (4), 1498, 2013 | 36 | 2013 |
| Meningeal norepinephrine produces headache behaviors in rats via actions both on dural afferents and fibroblasts X Wei, J Yan, D Tillu, M Asiedu, N Weinstein, O Melemedjian, T Price, ... Cephalalgia 35 (12), 1054-1064, 2015 | 27 | 2015 |
| Development and Evaluation of Small Peptidomimetic Ligands to Protease-Activated Receptor-2 (PAR2) through the Use of Lipid Tethering S Boitano, J Hoffman, DV Tillu, MN Asiedu, Z Zhang, CL Sherwood, ... PLoS One 9 (6), e99140, 2014 | 24 | 2014 |
| Lanthanide labeling of a potent protease activated receptor-2 agonist for time-resolved fluorescence analysis J Hoffman, AN Flynn, DV Tillu, Z Zhang, R Patek, TJ Price, J Vagner, ... Bioconjugate chemistry 23 (10), 2098-2104, 2012 | 20 | 2012 |
| Correction: Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain K Hanamura, HR Washburn, SI Sheffler-Collins, NL Xia, N Henderson, ... Plos Biology 19 (11), e3001452, 2021 | 1 | 2021 |
| Methods and compositions using ampk activators for pharmacological prevention of chronic pain TJ Price, G Dussor, D Tillu, B Lian US Patent App. 16/029,219, 2018 | 1 | 2018 |
