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| Subclonal reconstruction of tumors by using machine learning and population genetics G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ... Nature genetics 52 (9), 898-907, 2020 | 105 | 2020 |
| Exploiting evolutionary steering to induce collateral drug sensitivity in cancer A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ... Nature communications 11 (1), 1923, 2020 | 104 | 2020 |
| Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature 611 (7937), 744-753, 2022 | 101 | 2022 |
| Intra-tumor genetic heterogeneity in Wilms tumor: clonal evolution and clinical implications GD Cresswell, JR Apps, T Chagtai, B Mifsud, CC Bentley, M Maschietto, ... EBioMedicine 9, 120-129, 2016 | 82 | 2016 |
| The co-evolution of the genome and epigenome in colorectal cancer T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ... Nature 611 (7937), 733-743, 2022 | 72 | 2022 |
| Evolutionary dynamics of residual disease in human glioblastoma I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ... Annals of Oncology 30 (3), 456-463, 2019 | 72 | 2019 |
| Measuring single cell divisions in human tissues from multi-region sequencing data B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ... Nature communications 11 (1), 1035, 2020 | 64 | 2020 |
| Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking GD Cresswell, D Nichol, I Spiteri, H Tari, L Zapata, T Heide, CC Maley, ... Nature communications 11 (1), 1446, 2020 | 45 | 2020 |
| The spatiotemporal evolution of lymph node spread in early breast cancer P Barry, A Vatsiou, I Spiteri, D Nichol, GD Cresswell, A Acar, N Trahearn, ... Clinical Cancer Research 24 (19), 4763-4770, 2018 | 39 | 2018 |
| EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers EC Smyth, G Vlachogiannis, S Hedayat, A Harbery, S Hulkki-Wilson, ... Gut 70 (9), 1632-1641, 2021 | 36 | 2021 |
| Somatic TP53 mutations are detectable in circulating tumor DNA from children with anaplastic Wilms tumors TD Treger, T Chagtai, R Butcher, GD Cresswell, R Al-Saadi, J Brok, ... Translational Oncology 11 (6), 1301-1306, 2018 | 26 | 2018 |
| Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation SM Blake, SH Stricker, H Halavach, AR Poetsch, G Cresswell, G Kelly, ... Elife 5, e08711, 2016 | 22 | 2016 |
| Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer W Cross, M Mossner, S Nowinski, G Cresswell, A Banerjee, M Williams, ... Biorxiv, 2020.03. 26.007138, 2020 | 15 | 2020 |
| Exploiting evolutionary herding to control drug resistance in cancer A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ... BioRxiv, 566950, 2019 | 9 | 2019 |
| Long-term multimodal recording reveals epigenetic adaptation routes in dormant breast cancer cells D Rosano, E Sofyali, H Dhiman, C Ghirardi, D Ivanoiu, T Heide, ... Cancer Discovery 14 (5), 866-889, 2024 | 6 | 2024 |
| Model-based tumor subclonal reconstruction G Caravagna, T Heide, M Williams, L Zapata, D Nichol, K Chkhaidze, ... BioRxiv, 586560, 2019 | 6 | 2019 |
| Measuring single cell divisions in human cancers from multi-region sequencing data B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ... BioRxiv, 560243, 2019 | 4 | 2019 |
| A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations IM Saldana-Guerrero, LF Montano-Gutierrez, K Boswell, C Hafemeister, ... Nature Communications 15 (1), 3745, 2024 | 3 | 2024 |
| Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping J Fernandez-Mateos, S Milite, E Oliveira, G Vlachogiannis, B Chen, ... bioRxiv, 2023.11. 15.567140, 2023 | 2 | 2023 |
