Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial C Grigor, H Capell, A Stirling, AD McMahon, P Lock, R Vallance, D Porter, ... The Lancet 364 (9430), 263-269, 2004 | 1873 | 2004 |
Invadopodia: at the cutting edge of tumour invasion SS Stylli, AH Kaye, P Lock Journal of clinical neuroscience 15 (7), 725-737, 2008 | 256 | 2008 |
Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling ID Lawrenson, SH Wimmer-Kleikamp, P Lock, SM Schoenwaelder, ... Journal of cell science 115 (5), 1059-1072, 2002 | 225 | 2002 |
A new method for isolating tyrosine kinase substrates used to identify Fish, an SH3 and PX domain‐containing protein, and Src substrate P Lock, CL Abram, T Gibson, SA Courtneidge The EMBO journal, 1998 | 208 | 1998 |
Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation SS Stylli, STT I, AM Verhagen, SS Xu, I Pass, SA Courtneidge, P Lock Journal of cell science 122 (15), 2727-2740, 2009 | 168 | 2009 |
Two Isoforms of Murine hck, Generated by Utilization of Alternative Translational Initiation Codons, Exhibit Different Patterns of Subcellular Localization P Lock, S Ralph, E Stanley, I Boulet, R Ramsay, AR Dunn Molecular and Cellular Biology 11 (9), 4363-4370, 1991 | 151 | 1991 |
Primary structure of the (1→ 3, 1→ 4)-β-D-glucan 4-glucohydrolase from barley aleurone GB Fincher, PA Lock, MM Morgan, K Lingelbach, REH Wettenhall, ... Proceedings of the National Academy of Sciences 83 (7), 2081-2085, 1986 | 145 | 1986 |
RIPK1-and RIPK3-induced cell death mode is determined by target availability WD Cook, DM Moujalled, TJ Ralph, P Lock, SN Young, JM Murphy, ... Cell Death & Differentiation 21 (10), 1600-1612, 2014 | 144 | 2014 |
Lipopolysaccharide-and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages. I Boulet, S Ralph, E Stanley, P Lock, AR Dunn, SP Green, WA Phillips Oncogene 7 (4), 703-710, 1992 | 142 | 1992 |
The structure and dynamics of 2-dimensional fluids in swelling clays NT Skipper, PA Lock, JO Titiloye, J Swenson, ZA Mirza, WS Howells, ... Chemical geology 230 (3-4), 182-196, 2006 | 140 | 2006 |
Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS KY Soo, M Halloran, V Sundaramoorthy, S Parakh, RP Toth, KA Southam, ... Acta neuropathologica 130, 679-697, 2015 | 130 | 2015 |
The mitogen-induced increase in T cell size involves PKC and NFAT activation of Rel/NF-κB-dependent c-myc expression R Grumont, P Lock, M Mollinari, FM Shannon, A Moore, S Gerondakis Immunity 21 (1), 19-30, 2004 | 129 | 2004 |
Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling K Zhao, M Bleackley, D Chisanga, L Gangoda, P Fonseka, M Liem, ... Communications biology 2 (1), 305, 2019 | 119 | 2019 |
The human p62 cDNA encodes Sam68 and not the RasGAP-associated p62 protein P Lock, S Fumagalli, P Polakis, F McCormick, SA Courtneidge Cell 84 (1), 23-24, 1996 | 88 | 1996 |
Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck P Lock, F Casagranda, AR Dunn Journal of Biological Chemistry 274 (32), 22775-22784, 1999 | 87 | 1999 |
Loss of host type-I IFN signaling accelerates metastasis and impairs NK-cell antitumor function in multiple models of breast cancer J Rautela, N Baschuk, CY Slaney, KM Jayatilleke, K Xiao, BN Bidwell, ... Cancer immunology research 3 (11), 1207-1217, 2015 | 81 | 2015 |
Alternatively spliced murine lyn mRNAs encode distinct proteins E Stanley, S Ralph, S Mcewen, I Boulet, DA Holtzman, P Lock, AR Dunn Molecular and Cellular Biology, 1991 | 80 | 1991 |
Histidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor. P Lock, D Metcalf, NA Nicola Proceedings of the National Academy of Sciences 91 (1), 252-256, 1994 | 72 | 1994 |
Cross-species receptor binding characteristics of human and mouse leukemia inhibitory factor suggest a complex binding interaction. MJ Layton, P Lock, D Metcalf, NA Nicola Journal of Biological Chemistry 269 (25), 17048-17055, 1994 | 60 | 1994 |
ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner TTI Stacey, Z Nie, A Stewart, M Najdovska, NE Hall, H He, PA Randazzo, ... Journal of Cell Science 117 (25), 6071-6084, 2004 | 58 | 2004 |