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Juan R. Del Valle
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Agonist-mediated activation of STING induces apoptosis in malignant B cells
CHA Tang, JA Zundell, S Ranatunga, C Lin, Y Nefedova, JR Del Valle, ...
Cancer research 76 (8), 2137-2152, 2016
2712016
Chemistry and biology of the aeruginosin family of serine protease inhibitors
K Ersmark, JR Del Valle, S Hanessian
Angewandte Chemie International Edition 47 (7), 1202-1223, 2008
2062008
Inhibition of ER stress–associated IRE-1/XBP-1 pathway reduces leukemic cell survival
CHA Tang, S Ranatunga, CL Kriss, CL Cubitt, J Tao, JA Pinilla-Ibarz, ...
The Journal of clinical investigation 124 (6), 2585-2598, 2014
1842014
Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival
SJ Tavernier, F Osorio, L Vandersarren, J Vetters, N Vanlangenakker, ...
Nature cell biology 19 (6), 698-710, 2017
1142017
Total synthesis of pactamycin
BDS Prof. Dr. Stephen Hanessian, Dr. Ramkrishna Reddy Vakiti, Stéphane ...
Angewandte Chemie International Edition 50 (15), 3497-3500, 2011
110*2011
IRE1α RNase–dependent lipid homeostasis promotes survival in Myc-transformed cancers
H Xie, CHA Tang, JH Song, A Mancuso, JR Del Valle, J Cao, Y Xiang, ...
The Journal of clinical investigation 128 (4), 1300-1316, 2018
1072018
Stereoselective Synthesis of Boc‐Protected cis and trans‐4‐Trifluoromethylprolines by Asymmetric Hydrogenation Reactions
JR Del Valle, M Goodman
Angewandte Chemie 114 (9), 1670-1672, 2002
892002
Total synthesis and structural confirmation of chlorodysinosin A
S Hanessian, JR Del Valle, Y Xue, N Blomberg
Journal of the American Chemical Society 128 (32), 10491-10495, 2006
842006
Total synthesis and structural confirmation of chlorodysinosin A
S Hanessian, JR Del Valle, Y Xue, N Blomberg
Journal of the American Chemical Society 128 (32), 10491-10495, 2006
842006
Asymmetric hydrogenations for the synthesis of Boc-protected 4-alkylprolinols and prolines
JR Del Valle, M Goodman
The Journal of Organic Chemistry 68 (10), 3923-3931, 2003
832003
Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice
CL Kriss, JA Pinilla-Ibarz, AW Mailloux, JJ Powers, CHA Tang, CW Kang, ...
Blood, The Journal of the American Society of Hematology 120 (5), 1027-1038, 2012
762012
Adaptive endoplasmic reticulum stress signalling via IRE1α–XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells
L Liu, M Zhao, X Jin, G Ney, KB Yang, F Peng, J Cao, T Iwawaki, ...
Nature cell biology 21 (3), 328-337, 2019
692019
Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization
CHA Tang, S Chang, AW Paton, JC Paton, DI Gabrilovich, HL Ploegh, ...
Journal of Cell Biology 217 (5), 1739-1755, 2018
622018
Synthetic Studies in the Intramolecular Carbocyclization of N-Acyloxyiminium Ions. Stereoelectronic and Steric Implications of Nucleophilic Alkene, Alkyne, and …
S Hanessian, M Tremblay, M Marzi, JR Del Valle
The Journal of organic chemistry 70 (13), 5070-5085, 2005
532005
Peptide N‐Amination Supports β‐Sheet Conformations
MP Sarnowski, CW Kang, YM Elbatrawi, L Wojtas, JR Del Valle
Angewandte Chemie International Edition 56 (8), 2083-2086, 2017
462017
Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity
S Ranatunga, CHA Tang, CW Kang, CL Kriss, BJ Kloppenburg, CCA Hu, ...
Journal of medicinal chemistry 57 (10), 4289-4301, 2014
422014
Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin
S Hanessian, K Ersmark, X Wang, JR Del Valle, N Blomberg, Y Xue, ...
Bioorganic & medicinal chemistry letters 17 (12), 3480-3485, 2007
392007
Access to Enantiopure α-Hydrazino Acids for N-Amino Peptide Synthesis
CW Kang, MP Sarnowski, YM Elbatrawi, JR Del Valle
The Journal of Organic Chemistry 82 (3), 1833-1841, 2017
312017
Total synthesis and structural revision of the presumed aeruginosins 205A and B
S Hanessian, X Wang, K Ersmark, JR Del Valle, E Klegraf
Organic Letters 11 (18), 4232-4235, 2009
312009
Alkynyl Prins and Alkynyl Aza-Prins Annulations: Scope and Synthetic Applications
S Abdul-Rashed, C Holt, AJ Frontier
Synthesis 52 (14), 1991-2007, 2020
252020
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