Folgen
Philip A. Romero
Philip A. Romero
Biomedical Engineering, Duke University
Bestätigte E-Mail-Adresse bei duke.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Exploring protein fitness landscapes by directed evolution
PA Romero, FH Arnold
Nature reviews Molecular cell biology 10 (12), 866-876, 2009
13032009
Navigating the protein fitness landscape with Gaussian processes
PA Romero, A Krause, FH Arnold
Proceedings of the National Academy of Sciences 110 (3), E193-E201, 2013
3952013
Dissecting enzyme function with microfluidic-based deep mutational scanning
PA Romero, TM Tran, AR Abate
Proceedings of the National Academy of Sciences 112 (23), 7159-7164, 2015
2512015
Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine
MG Shapiro, GG Westmeyer, PA Romero, JO Szablowski, B Küster, ...
Nature biotechnology 28 (3), 264-270, 2010
2032010
Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution
JD Bloom, PA Romero, Z Lu, FH Arnold
Biology direct 2, 1-19, 2007
1942007
Neural networks to learn protein sequence–function relationships from deep mutational scanning data
S Gelman, SA Fahlberg, P Heinzelman, PA Romero, A Gitter
Proceedings of the National Academy of Sciences 118 (48), e2104878118, 2021
1262021
Efficient screening of fungal cellobiohydrolase class I enzymes for thermostabilizing sequence blocks by SCHEMA structure-guided recombination
P Heinzelman, R Komor, A Kanaan, P Romero, X Yu, S Mohler, C Snow, ...
Protein Engineering, Design & Selection 23 (11), 871-880, 2010
1212010
In vivo selection of a computationally designed SCHEMA AAV library yields a novel variant for infection of adult neural stem cells in the SVZ
DS Ojala, S Sun, JL Santiago-Ortiz, MG Shapiro, PA Romero, DV Schaffer
Molecular Therapy 26 (1), 304-319, 2018
1192018
Microbial interaction network inference in microfluidic droplets
RH Hsu, RL Clark, JW Tan, JC Ahn, S Gupta, PA Romero, OS Venturelli
Cell systems 9 (3), 229-242. e4, 2019
1092019
Investigating the dynamics of microbial consortia in spatially structured environments
S Gupta, TD Ross, MM Gomez, JL Grant, PA Romero, OS Venturelli
Nature communications 11 (1), 2418, 2020
832020
Highly thermostable fungal cellobiohydrolase I (Cel7A) engineered using predictive methods
RS Komor, PA Romero, CB Xie, FH Arnold
Protein Engineering, Design & Selection 25 (12), 827-833, 2012
812012
Machine learning-guided acyl-ACP reductase engineering for improved in vivo fatty alcohol production
JC Greenhalgh, SA Fahlberg, BF Pfleger, PA Romero
Nature communications 12 (1), 5825, 2021
752021
Machine learning to navigate fitness landscapes for protein engineering
CR Freschlin, SA Fahlberg, PA Romero
Current opinion in biotechnology 75, 102713, 2022
682022
SCHEMA-designed variants of human arginase I and II reveal sequence elements important to stability and catalysis
PA Romero, E Stone, C Lamb, L Chantranupong, A Krause, AE Miklos, ...
ACS synthetic biology 1 (6), 221-228, 2012
632012
Flow focusing geometry generates droplets through a plug and squeeze mechanism
PA Romero, AR Abate
Lab on a Chip 12 (24), 5130-5132, 2012
572012
Inferring protein sequence-function relationships with large-scale positive-unlabeled learning
H Song, BJ Bremer, EC Hinds, G Raskutti, PA Romero
Cell systems 12 (1), 92-101. e8, 2021
532021
Self-driving laboratories to autonomously navigate the protein fitness landscape
JT Rapp, BJ Bremer, PA Romero
Nature chemical engineering 1 (1), 97-107, 2024
392024
Chimeragenesis of distantly‐related proteins by noncontiguous recombination
MA Smith, PA Romero, T Wu, EM Brustad, FH Arnold
Protein science 22 (2), 231-238, 2013
372013
Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation
H Roychowdhury, PA Romero
Cell Death Discovery 8, 2022
202022
Efficient sampling of SCHEMA chimera families to identify useful sequence elements
P Heinzelman, PA Romero, FH Arnold
Methods in enzymology 523, 351-368, 2013
182013
Das System kann den Vorgang jetzt nicht ausführen. Versuchen Sie es später erneut.
Artikel 1–20