Philipp Koch
Philipp Koch
Central Institute of Mental Health and Hector Institut for Translational Brain Research
Verified email at zi-mannheim.de
TitleCited byYear
A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration
P Koch, T Opitz, JA Steinbeck, J Ladewig, O Brüstle
Proceedings of the National Academy of Sciences 106 (9), 3225-3230, 2009
4632009
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease
P Koch, P Breuer, M Peitz, J Jungverdorben, J Kesavan, D Poppe, J Doerr, ...
Nature 480 (7378), 543, 2011
2612011
Small molecules enable highly efficient neuronal conversion of human fibroblasts
J Ladewig, J Mertens, J Kesavan, J Doerr, D Poppe, F Glaue, S Herms, ...
Nature methods 9 (6), 575, 2012
2592012
Human‐induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke‐damaged brain
K Oki, J Tatarishvili, J Wood, P Koch, S Wattananit, Y Mine, E Monni, ...
Stem cells 30 (6), 1120-1133, 2012
2312012
Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons
A Falk, P Koch, J Kesavan, Y Takashima, J Ladewig, M Alexander, ...
PloS one 7 (1), e29597, 2012
2062012
Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies
J Ladewig, P Koch, O Brüstle
Nature reviews Molecular cell biology 14 (4), 225, 2013
2022013
Inhibition of Notch Signaling in Human Embryonic Stem Cell–Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and …
L Borghese, D Dolezalova, T Opitz, S Haupt, A Leinhaas, B Steinfarz, ...
Stem cells 28 (5), 955-964, 2010
1762010
Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery
D Tornero, S Wattananit, M Grønning Madsen, P Koch, J Wood, ...
Brain 136 (12), 3561-3577, 2013
1512013
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants
T Li, JA Steinbeck, T Lusardi, P Koch, JQ Lan, A Wilz, M Segschneider, ...
Brain 130 (5), 1276-1288, 2007
1482007
Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase
L Nolden, F Edenhofer, S Haupt, P Koch, FT Wunderlich, H Siemen, ...
Nature methods 3 (6), 461, 2006
1352006
Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling
P Koch, Z Kokaia, O Lindvall, O Brüstle
The Lancet Neurology 8 (9), 819-829, 2009
1182009
The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair
NS Corsini, I Sancho-Martinez, S Laudenklos, D Glagow, S Kumar, ...
Cell Stem Cell 5 (2), 178-190, 2009
1152009
Nucleofection of human embryonic stem cells
H Siemen, M Nix, E Endl, P Koch, J Itskovitz-Eldor, O Brüstle
Stem Cells and Development 14 (4), 378-383, 2005
1062005
Presenilin-1 L166P mutant human pluripotent stem cell–derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation
P Koch, IY Tamboli, J Mertens, P Wunderlich, J Ladewig, K Stüber, ...
The American journal of pathology 180 (6), 2404-2416, 2012
932012
Anticancer effects of niclosamide in human glioblastoma
A Wieland, D Trageser, S Gogolok, R Reinartz, H Höfer, M Keller, ...
Clinical Cancer Research 19 (15), 4124-4136, 2013
872013
MicroRNA-based promotion of human neuronal differentiation and subtype specification
L Stappert, L Borghese, B Roese-Koerner, S Weinhold, P Koch, ...
PloS one 8 (3), e59011, 2013
682013
Interinstitutional variance of postoperative radiotherapy and follow up for meningiomas in Germany: impact of changes of the WHO classification
M Simon, J Boström, P Koch, J Schramm
Journal of Neurology, Neurosurgery & Psychiatry 77 (6), 767-773, 2006
662006
Generation of functional human serotonergic neurons from fibroblasts
KC Vadodaria, J Mertens, A Paquola, C Bardy, X Li, R Jappelli, L Fung, ...
Molecular psychiatry 21 (1), 49, 2016
632016
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat
T Milde, S Kleber, A Korshunov, H Witt, T Hielscher, P Koch, HG Kopp, ...
Acta neuropathologica 122 (5), 637, 2011
612011
An organoid-based model of cortical development identifies non-cell-autonomous defects in Wnt signaling contributing to Miller-Dieker syndrome
V Iefremova, G Manikakis, O Krefft, A Jabali, K Weynans, R Wilkens, ...
Cell reports 19 (1), 50-59, 2017
572017
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