Philipp Koch
Philipp Koch
Central Institute of Mental Health and Hector Institut for Translational Brain Research
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Cited by
Cited by
A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration
P Koch, T Opitz, JA Steinbeck, J Ladewig, O Brüstle
Proceedings of the National Academy of Sciences 106 (9), 3225-3230, 2009
Small molecules enable highly efficient neuronal conversion of human fibroblasts
J Ladewig, J Mertens, J Kesavan, J Doerr, D Poppe, F Glaue, S Herms, ...
Nature methods 9 (6), 575-578, 2012
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease
P Koch, P Breuer, M Peitz, J Jungverdorben, J Kesavan, D Poppe, J Doerr, ...
Nature 480 (7378), 543-546, 2011
Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain
K Oki, J Tatarishvili, J Wood, P Koch, S Wattananit, Y Mine, E Monni, ...
Stem cells 30 (6), 1120-1133, 2012
Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons
A Falk, P Koch, J Kesavan, Y Takashima, J Ladewig, M Alexander, ...
PloS one 7 (1), e29597, 2012
Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies
J Ladewig, P Koch, O Brüstle
Nature reviews Molecular cell biology 14 (4), 225-236, 2013
Inhibition of Notch Signaling in Human Embryonic Stem Cell–Derived Neural Stem Cells Delays G1/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and …
L Borghese, D Dolezalova, T Opitz, S Haupt, A Leinhaas, B Steinfarz, ...
Stem cells 28 (5), 955-964, 2010
Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery
D Tornero, S Wattananit, M Grønning Madsen, P Koch, J Wood, ...
Brain 136 (12), 3561-3577, 2013
An organoid-based model of cortical development identifies non-cell-autonomous defects in Wnt signaling contributing to Miller-Dieker syndrome
V Iefremova, G Manikakis, O Krefft, A Jabali, K Weynans, R Wilkens, ...
Cell reports 19 (1), 50-59, 2017
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants
T Li, JA Steinbeck, T Lusardi, P Koch, JQ Lan, A Wilz, M Segschneider, ...
Brain 130 (5), 1276-1288, 2007
Anticancer effects of niclosamide in human glioblastoma
A Wieland, D Trageser, S Gogolok, R Reinartz, H Höfer, M Keller, ...
Clinical Cancer Research 19 (15), 4124-4136, 2013
Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase
L Nolden, F Edenhofer, S Haupt, P Koch, FT Wunderlich, H Siemen, ...
Nature methods 3 (6), 461-467, 2006
The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair
NS Corsini, I Sancho-Martinez, S Laudenklos, D Glagow, S Kumar, ...
Cell stem cell 5 (2), 178-190, 2009
Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling
P Koch, Z Kokaia, O Lindvall, O Brüstle
The Lancet Neurology 8 (9), 819-829, 2009
Presenilin-1 L166P mutant human pluripotent stem cell–derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation
P Koch, IY Tamboli, J Mertens, P Wunderlich, J Ladewig, K Stüber, ...
The American journal of pathology 180 (6), 2404-2416, 2012
Generation of functional human serotonergic neurons from fibroblasts
KC Vadodaria, J Mertens, A Paquola, C Bardy, X Li, R Jappelli, L Fung, ...
Molecular psychiatry 21 (1), 49-61, 2016
Specific inhibition of β-secretase processing of the Alzheimer disease amyloid precursor protein
SB Halima, S Mishra, KMP Raja, M Willem, A Baici, K Simons, O Brüstle, ...
Cell reports 14 (9), 2127-2141, 2016
Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing
P Giesselmann, B Brändl, E Raimondeau, R Bowen, C Rohrandt, ...
Nature Biotechnology 37 (12), 1478-1481, 2019
Nucleofection of human embryonic stem cells
H Siemen, M Nix, E Endl, P Koch, J Itskovitz-Eldor, O Brüstle
Stem Cells and Development 14 (4), 378-383, 2005
MicroRNA-based promotion of human neuronal differentiation and subtype specification
L Stappert, L Borghese, B Roese-Koerner, S Weinhold, P Koch, ...
PloS one 8 (3), e59011, 2013
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