| Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis N Singh, A Gurav, S Sivaprakasam, E Brady, R Padia, H Shi, ... Immunity 40 (1), 128-139, 2014 | 2014 | 2014 |
| Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond V Ganapathy, M Thangaraju, PD Prasad Pharmacology & therapeutics 121 (1), 29-40, 2009 | 814 | 2009 |
| GPR109A is a G-protein–coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon M Thangaraju, GA Cresci, K Liu, S Ananth, JP Gnanaprakasam, ... Cancer research 69 (7), 2826-2832, 2009 | 727 | 2009 |
| Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis. U Kumar, R Sasi, S Suresh, A Patel, M Thangaraju, P Metrakos, SC Patel, ... diabetes 48 (1), 77-85, 1999 | 337 | 1999 |
| Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade M Ouzounova, E Lee, R Piranlioglu, A El Andaloussi, R Kolhe, ... Nature communications 8 (1), 14979, 2017 | 335 | 2017 |
| Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells MA Zimmerman, N Singh, PM Martin, M Thangaraju, V Ganapathy, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 302 (12 …, 2012 | 313 | 2012 |
| Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host V Ganapathy, M Thangaraju, PD Prasad, PM Martin, N Singh Current opinion in pharmacology 13 (6), 869-874, 2013 | 294 | 2013 |
| Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases N Singh, M Thangaraju, PD Prasad, PM Martin, NA Lambert, T Boettger, ... Journal of Biological Chemistry 285 (36), 27601-27608, 2010 | 286 | 2010 |
| DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis R Pathania, S Ramachandran, S Elangovan, R Padia, P Yang, S Cinghu, ... Nature communications 6 (1), 6910, 2015 | 251 | 2015 |
| Sodium-coupled monocarboxylate transporters in normal tissues and in cancer V Ganapathy, M Thangaraju, E Gopal, PM Martin, S Itagaki, S Miyauchi, ... The AAPS journal 10, 193-199, 2008 | 246 | 2008 |
| SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive … S Karunakaran, S Ramachandran, V Coothankandaswamy, S Elangovan, ... Journal of Biological Chemistry 286 (36), 31830-31838, 2011 | 218 | 2011 |
| BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines M Thangaraju, SH Kaufmann, FJ Couch Journal of Biological Chemistry 275 (43), 33487-33496, 2000 | 196 | 2000 |
| Ratio of miR-196s to HOXC8 messenger RNA correlates with breast cancer cell migration and metastasis Y Li, M Zhang, H Chen, Z Dong, V Ganapathy, M Thangaraju, S Huang Cancer research 70 (20), 7894-7904, 2010 | 190 | 2010 |
| SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer S Elangovan, S Ramachandran, N Venkatesan, S Ananth, ... Cancer research 71 (21), 6654-6664, 2011 | 175 | 2011 |
| NF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression F Liu, K Bardhan, D Yang, M Thangaraju, V Ganapathy, JL Waller, ... Journal of Biological Chemistry 287 (30), 25530-25540, 2012 | 173 | 2012 |
| Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3 M Thangaraju, KN Carswell, PD Prasad, V Ganapathy Biochemical Journal 417 (1), 379-389, 2009 | 168 | 2009 |
| Caspase-8-mediated intracellular acidification precedes mitochondrial dysfunction in somatostatin-induced apoptosis D Liu, G Martino, M Thangaraju, M Sharma, F Halwani, SH Shen, ... Journal of Biological Chemistry 275 (13), 9244-9250, 2000 | 165 | 2000 |
| SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases M Thangaraju, E Gopal, PM Martin, S Ananth, SB Smith, PD Prasad, ... Cancer research 66 (24), 11560-11564, 2006 | 160 | 2006 |
| Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth R Pathania, S Ramachandran, G Mariappan, P Thakur, H Shi, JH Choi, ... Cancer research 76 (11), 3224-3235, 2016 | 156 | 2016 |
| Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8 GA Cresci, M Thangaraju, JD Mellinger, K Liu, V Ganapathy Journal of Gastrointestinal Surgery 14 (3), 449-461, 2010 | 156 | 2010 |
