| An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex Y Zhang, K Chen, SA Sloan, ML Bennett, AR Scholze, S O'Keeffe, ... Journal of neuroscience 34 (36), 11929-11947, 2014 | 4644 | 2014 |
| Phosphorylation and functions of the RNA polymerase II CTD HP Phatnani, AL Greenleaf Genes & development 20 (21), 2922-2936, 2006 | 931 | 2006 |
| A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model IM Chiu, ETA Morimoto, H Goodarzi, JT Liao, S O’Keeffe, HP Phatnani, ... Cell reports 4 (2), 385-401, 2013 | 653 | 2013 |
| A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation KO Kizer, HP Phatnani, Y Shibata, H Hall, AL Greenleaf, BD Strahl Molecular and cellular biology 25 (8), 3305-3316, 2005 | 601 | 2005 |
| Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1268-1283. e6, 2018 | 576 | 2018 |
| Identification of required host factors for SARS-CoV-2 infection in human cells Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ... Cell 184 (1), 92-105. e16, 2021 | 505 | 2021 |
| CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 B Bartkowiak, P Liu, HP Phatnani, NJ Fuda, JJ Cooper, DH Price, ... Genes & development 24 (20), 2303-2316, 2010 | 447 | 2010 |
| Astrocytes in neurodegenerative disease H Phatnani, T Maniatis Cold Spring Harbor perspectives in biology 7 (6), a020628, 2015 | 429 | 2015 |
| Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability B Bilican, A Serio, SJ Barmada, AL Nishimura, GJ Sullivan, M Carrasco, ... Proceedings of the National Academy of Sciences 109 (15), 5803-5808, 2012 | 405 | 2012 |
| Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy A Serio, B Bilican, SJ Barmada, DM Ando, C Zhao, R Siller, K Burr, ... Proceedings of the National Academy of Sciences 110 (12), 4697-4702, 2013 | 392 | 2013 |
| An efficient platform for astrocyte differentiation from human induced pluripotent stem cells TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ... Stem cell reports 9 (2), 600-614, 2017 | 361 | 2017 |
| Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis S Maniatis, T Äijö, S Vickovic, C Braine, K Kang, A Mollbrink, ... Science 364 (6435), 89-93, 2019 | 344 | 2019 |
| Postmortem cortex samples identify distinct molecular subtypes of ALS: retrotransposon activation, oxidative stress, and activated glia OH Tam, NV Rozhkov, R Shaw, D Kim, I Hubbard, S Fennessey, N Propp, ... Cell reports 29 (5), 1164-1177. e5, 2019 | 217 | 2019 |
| TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ... Nature 603 (7899), 131-137, 2022 | 210 | 2022 |
| Synergistic effects of common schizophrenia risk variants N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ... Nature genetics 51 (10), 1475-1485, 2019 | 202 | 2019 |
| Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice IM Chiu, H Phatnani, M Kuligowski, JC Tapia, MA Carrasco, M Zhang, ... Proceedings of the National Academy of Sciences 106 (49), 20960-20965, 2009 | 202 | 2009 |
| Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3′-end formation DP Morris, HP Phatnani, AL Greenleaf Journal of Biological Chemistry 274 (44), 31583-31587, 1999 | 188 | 1999 |
| C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats JC Jones, HP Phatnani, TA Haystead, JA MacDonald, SM Alam, ... Journal of Biological Chemistry 279 (24), 24957-24964, 2004 | 170 | 2004 |
| Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome HP Phatnani, JC Jones, AL Greenleaf Biochemistry 43 (50), 15702-15719, 2004 | 152 | 2004 |
| Intricate interplay between astrocytes and motor neurons in ALS HP Phatnani, P Guarnieri, BA Friedman, MA Carrasco, M Muratet, ... Proceedings of the National Academy of Sciences 110 (8), E756-E765, 2013 | 149 | 2013 |
Tom ManiatisDepartment of Biochemistry and Molecular Biophysics, Columbia UniversityVerified email at columbia.edu
