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Martin C. Heiss
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Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures
ML Fernández-Quintero, MC Heiss, ND Pomarici, BA Math, KR Liedl
MAbs 12 (1), 1744328, 2020
312020
Surprisingly fast interface and elbow angle dynamics of antigen-binding fragments
ML Fernández-Quintero, KB Kroell, MC Heiss, JR Loeffler, PK Quoika, ...
Frontiers in Molecular Biosciences 7, 609088, 2020
222020
Antibody humanization—the Influence of the antibody framework on the CDR-H3 loop ensemble in solution
ML Fernández-Quintero, MC Heiss, KR Liedl
Protein Engineering, Design and Selection 32 (9), 411-422, 2019
192019
CaV1.1 voltage-sensing domain III exclusively controls skeletal muscle excitation-contraction coupling
S Pelizzari, MC Heiss, ML Fernández-Quintero, Y El Ghaleb, KR Liedl, ...
Nature Communications 15 (1), 7440, 2024
2024
Role of the charge transfer center as a bimodal regulator of voltage-dependence and kinetics of CaV voltage sensor action
MC Heiss, ML Fernandez-Quintero, S Pelizzari, Y El Ghaleb, M Campiglio, ...
Biophysical Journal 123 (3), 113a, 2024
2024
Characterizing the role of voltage-sensing domains of CaV3. 3 determining gating properties
ALM Fischer, MC Heiss, Y El Ghaleb, JR Löffler, KR Liedl, BE Flucher, ...
Biophysical Journal 123 (3), 114a, 2024
2024
The extracellular S3-S4 loop of CaV1. 1 voltage-sensors as specific modulator of EC coupling and calcium currents
S Pelizzari, ML Fernandez-Quintero, M Campiglio, MC Heiss, Y El Ghaleb, ...
Biophysical Journal 123 (3), 113a-114a, 2024
2024
Identifying the CaV1. 1 voltage-sensing domains involved in channel gating and excitation contraction coupling
S Pelizzari, ML Fernandez-Quintero, M Campiglio, P Tuluc, Y El Ghaleb, ...
Biophysical Journal 122 (3), 376a-377a, 2023
2023
Ionic interactions between gating charges and countercharges in voltage-sensing domain I independently regulate kinetics and voltage-dependence of Cav1. 1 gating
MC Heiss, ML Fernandez-Quintero, S Pelizzari, Y El Ghaleb, M Campiglio, ...
Biophysical Journal 122 (3), 106a-107a, 2023
2023
Voltage-dependent transitions between resting and activated states of the four Cav1. 1 voltage sensors observed in MD simulation
ML Fernández-Quintero, S Pelizzari, Y El Ghaleb, MC Heiss, KR Liedl, ...
Biophysical Journal 122 (3), 106a, 2023
2023
Defining the roles of VSD II & III of Cav1. 1 in regulating calcium currents and EC-coupling
S Pelizzari, Y El Ghaleb, MC Heiss, ML Fernández-Quintero, P Tuluc, ...
Biophysical Journal 121 (3), 88a-89a, 2022
2022
Molecular mechanisms of disease-causing mutations in the first voltage-sensing domain of Cav1. 1
MC Heiss, ML Fernandez-Quintero, Y El Ghaleb, S Pelizzari, P Tuluc, ...
Biophysical Journal 121 (3), 90a, 2022
2022
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