| SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases GS Feng, CC Hui, T Pawson Science 259 (5101), 1607-1611, 1993 | 837 | 1993 |
| Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4 LEM Marengère, P Waterhouse, GS Duncan, HW Mittrücker, GS Feng, ... Science 272 (5265), 1170-1173, 1996 | 649 | 1996 |
| Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp‐2 TM Saxton, M Henkemeyer, S Gasca, R Shen, DJ Rossi, F Shalaby, ... The EMBO journal, 1997 | 561 | 1997 |
| Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion DH Yu, CK Qu, O Henegariu, X Lu, GS Feng Journal of Biological Chemistry 273 (33), 21125-21131, 1998 | 509 | 1998 |
| Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway M You, DH Yu, GS Feng Molecular and cellular biology, 1999 | 496 | 1999 |
| The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp MR Kuhne, T Pawson, GE Lienhard, GS Feng Journal of Biological Chemistry 268 (16), 11479-11481, 1993 | 478 | 1993 |
| PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase RJ Chan, GS Feng Blood 109 (3), 862-867, 2007 | 376 | 2007 |
| Shp-2 tyrosine phosphatase: signaling one cell or many GS Feng Experimental cell research 253 (1), 47-54, 1999 | 374 | 1999 |
| Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis EA Bard-Chapeau, S Li, J Ding, SS Zhang, HH Zhu, F Princen, DD Fang, ... Cancer cell 19 (5), 629-639, 2011 | 348 | 2011 |
| Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice. M Kozlowski, I Mlinaric-Rascan, GS Feng, R Shen, T Pawson, ... The Journal of experimental medicine 178 (6), 2157-2163, 1993 | 295 | 1993 |
| SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production H An, W Zhao, J Hou, Y Zhang, Y Xie, Y Zheng, H Xu, C Qian, J Zhou, ... Immunity 25 (6), 919-928, 2006 | 292 | 2006 |
| Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity ZQ Shi, DH Yu, M Park, M Marshall, GS Feng Molecular and cellular biology 20 (5), 1526-1536, 2000 | 286 | 2000 |
| Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism EE Zhang, E Chapeau, K Hagihara, GS Feng Proceedings of the National Academy of Sciences 101 (45), 16064-16069, 2004 | 275 | 2004 |
| The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. A Kazlauskas, GS Feng, T Pawson, M Valius Proceedings of the National Academy of Sciences 90 (15), 6939-6943, 1993 | 273 | 1993 |
| Nuclear factor high‐mobility group box1 mediating the activation of Toll‐like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice L Li, L Chen, L Hu, Y Liu, HY Sun, J Tang, YJ Hou, YX Chang, QQ Tu, ... Hepatology 54 (5), 1620-1630, 2011 | 266 | 2011 |
| Force‐dependent integrin–cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2 G Von Wichert, B Haimovich, GS Feng, MP Sheetz The EMBO journal, 2003 | 258 | 2003 |
| Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction GS Feng, T Pawson Trends in Genetics 10 (2), 54-58, 1994 | 258 | 1994 |
| Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma L Zheng, W Yang, F Wu, C Wang, L Yu, L Tang, B Qiu, Y Li, L Guo, M Wu, ... Clinical cancer research 19 (19), 5372-5380, 2013 | 243 | 2013 |
| Hepatic transforming growth factor beta gives rise to tumor‐initiating cells and promotes liver cancer development K Wu, J Ding, C Chen, W Sun, BF Ning, W Wen, L Huang, T Han, W Yang, ... Hepatology 56 (6), 2255-2267, 2012 | 235 | 2012 |
| SHP-2 is a dual-specificity phosphatase involved in Stat1 dephosphorylation at both tyrosine and serine residues in nuclei TR Wu, YK Hong, XD Wang, MY Ling, AM Dragoi, AS Chung, ... Journal of Biological Chemistry 277 (49), 47572-47580, 2002 | 221 | 2002 |
