| Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties JZ Nordin, Y Lee, P Vader, I Mäger, HJ Johansson, W Heusermann, ... Nanomedicine: Nanotechnology, Biology and Medicine 11 (4), 879-883, 2015 | 664 | 2015 |
| Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER W Heusermann, J Hean, D Trojer, E Steib, S Von Bueren, A Graff-Meyer, ... Journal of Cell Biology 213 (2), 173-184, 2016 | 410 | 2016 |
| The rough endoplasmatic reticulum is a central nucleation site of siRNA‐mediated RNA silencing L Stalder, W Heusermann, L Sokol, D Trojer, J Wirz, J Hean, A Fritzsche, ... The EMBO journal 32 (8), 1115-1127, 2013 | 266 | 2013 |
| Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR NC Meisner, M Hintersteiner, K Mueller, R Bauer, JM Seifert, HU Naegeli, ... Nature chemical biology 3 (8), 508-515, 2007 | 227 | 2007 |
| The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2 LE Young, AE Moore, L Sokol, N Meisner-Kober, DA Dixon Molecular Cancer Research 10 (1), 167-180, 2012 | 221 | 2012 |
| mRNA openers and closers: modulating AU‐rich element‐controlled mRNA stability by a molecular switch in mRNA secondary structure NC Meisner, J Hackermüller, V Uhl, A Aszódi, M Jaritz, M Auer Chembiochem 5 (10), 1432-1447, 2004 | 168 | 2004 |
| Highly complementary target RNAs promote release of guide RNAs from human Argonaute2 N De, L Young, PW Lau, NC Meisner, DV Morrissey, IJ MacRae Molecular cell 50 (3), 344-355, 2013 | 140 | 2013 |
| The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells FF Blanco, M Jimbo, J Wulfkuhle, I Gallagher, J Deng, L Enyenihi, ... Oncogene 35 (19), 2529-2541, 2016 | 128 | 2016 |
| Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule–single vesicle level by fluorescence correlation spectroscopy and … G Corso, W Heusermann, D Trojer, A Görgens, E Steib, J Voshol, A Graff, ... Journal of extracellular vesicles 8 (1), 1663043, 2019 | 123 | 2019 |
| Properties of the regulatory RNA-binding protein HuR and its role in controlling miRNA repression NC Meisner, W Filipowicz Regulation of microRNAs, 106-123, 2010 | 120 | 2010 |
| Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis FF Blanco, R Preet, A Aguado, V Vishwakarma, LE Stevens, A Vyas, ... Oncotarget 7 (45), 74043, 2016 | 102 | 2016 |
| Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM N Ripin, J Boudet, MM Duszczyk, A Hinniger, M Faller, M Krepl, A Gadi, ... Proceedings of the National Academy of Sciences 116 (8), 2935-2944, 2019 | 90 | 2019 |
| HuR small-molecule inhibitor elicits differential effects in adenomatosis polyposis and colorectal carcinogenesis M Lang, D Berry, K Passecker, I Mesteri, S Bhuju, F Ebner, V Sedlyarov, ... Cancer research 77 (9), 2424-2438, 2017 | 84 | 2017 |
| Single bead labeling method for combining confocal fluorescence on-bead screening and solution validation of tagged one-bead one-compound libraries M Hintersteiner, T Kimmerlin, F Kalthoff, M Stoeckli, G Garavel, JM Seifert, ... Chemistry & biology 16 (7), 724-735, 2009 | 81 | 2009 |
| Posttranscriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors SN Chand, M Zarei, MJ Schiewer, AR Kamath, C Romeo, S Lal, ... Cancer research 77 (18), 5011-5025, 2017 | 70 | 2017 |
| Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries M Hintersteiner, G Ambrus, J Bednenko, M Schmied, AJS Knox, ... ACS chemical biology 5 (10), 967-979, 2010 | 68 | 2010 |
| The effect of RNA secondary structures on RNA-ligand binding and the modifier RNA mechanism: a quantitative model J Hackermüller, NC Meisner, M Auer, M Jaritz, PF Stadler Gene 345 (1), 3-12, 2005 | 66 | 2005 |
| HuR contributes to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer cells C Romeo, MC Weber, M Zarei, D DeCicco, SN Chand, AD Lobo, ... Molecular Cancer Research 14 (7), 599-611, 2016 | 60 | 2016 |
| Structural basis of si RNA recognition by TRBP double‐stranded RNA binding domains G Masliah, C Maris, SLB König, M Yulikov, F Aeschimann, AL Malinowska, ... The EMBO journal 37 (6), e97089, 2018 | 56 | 2018 |
| Terminal adenosyl transferase activity of posttranscriptional regulator HuR revealed by confocal on-bead screening NC Meisner, M Hintersteiner, JM Seifert, R Bauer, RM Benoit, A Widmer, ... Journal of molecular biology 386 (2), 435-450, 2009 | 52 | 2009 |
Jordan Winter MDProfessor of surgery, University HospitalsVerified email at UHhospitals.org
