|Recon 2.2: from reconstruction to model of human metabolism|
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12 (7), 109, 2016
|A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism|
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell systems 3 (5), 434-443. e8, 2016
|Optimizing eukaryotic cell hosts for protein production through systems biotechnology and genome‐scale modeling|
JM Gutierrez, NE Lewis
Biotechnology journal 10 (7), 939-949, 2015
|Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow|
A Golabgir, JM Gutierrez, H Hefzi, S Li, BO Palsson, C Herwig, NE Lewis
Biotechnology advances 34 (5), 621-633, 2016
|The emerging role of systems biology for engineering protein production in CHO cells|
CC Kuo, AWT Chiang, I Shamie, M Samoudi, JM Gutierrez, NE Lewis
Current opinion in biotechnology 51, 64-69, 2018
|Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion|
JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ...
bioRxiv, 351387, 2018
|Combating viral contaminants in CHO cells by engineering innate immunity|
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
Scientific Reports 9 (1), 8827, 2019
|Multiplex secretome engineering enhances recombinant protein production and purity|
S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, JM Gutierrez, AWT Chiang, ...
bioRxiv, 647214, 2019
|The human secretome–the proteins secreted from human cells|
M Uhlen, H Tegel, Å Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ...
bioRxiv, 465815, 2018