Mary Wertz
Mary Wertz
Postdoc Broad Institute/MIT
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Cited by
Cited by
BACE1 regulates voltage-gated sodium channels and neuronal activity
DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ...
Nature cell biology 9 (7), 755-764, 2007
Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits
B Akten, MJ Kye, LT Hao, MH Wertz, S Singh, D Nie, J Huang, ...
Proceedings of the National Academy of Sciences 108 (25), 10337-10342, 2011
SMN regulates axonal local translation via miR-183/mTOR pathway
MJ Kye, ED Niederst, MH Wertz, ICG Gonçalves, B Akten, KZ Dover, ...
Human molecular genetics 23 (23), 6318-6331, 2014
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
A Di Nardo, MH Wertz, E Kwiatkowski, PT Tsai, JD Leech, ...
Human molecular genetics 23 (14), 3865-3874, 2014
Genome-wide in vivo CNS screening identifies genes that modify CNS neuronal survival and mHTT toxicity
MH Wertz, MR Mitchem, SS Pineda, LJ Hachigian, H Lee, V Lau, ...
Neuron 106 (1), 76-89. e8, 2020
Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy
MH Wertz, K Winden, P Neveu, SY Ng, E Ercan, M Sahin
Human molecular genetics 25 (11), 2168-2181, 2016
Characterization of the nuclear localization signal of high risk HPV16 E2 protein
K Klucevsek, M Wertz, J Lucchi, A Leszczynski, J Moroianu
Virology 360 (1), 191-198, 2007
Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis
SW Kong, M Sahin, CD Collins, MH Wertz, MG Campbell, JD Leech, ...
Molecular Autism 5 (1), 1-11, 2014
Developing therapies for spinal muscular atrophy
MH Wertz, M Sahin
Annals of the New York Academy of Sciences 1366 (1), 5-19, 2016
Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes
MH Wertz, SS Pineda, H Lee, R Kulicke, M Kellis, M Heiman
Molecular neurodegeneration 15, 1-8, 2020
d. CG, Akten, B
MJ Kye, ED Niederst, MH Wertz, I Gonçalves
Dover, KZ,... Sahin, M.(2014, dec). SMN regulates axonal local translation …, 2014
Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin
L Megret, B Gris, S Sasidharan Nair, J Cevost, M Wertz, J Aaronson, ...
Elife 10, e64984, 2021
C., Akten, B
MJ Kye, ED Niederst, MH Wertz, I Gonçalves
Dover, KZ, Peters, M., Riessland, M., Neveu, P., Wirth, B., et al, 2014
The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells
DY Kim, MH Wertz, V Gautam, C D'avanzo, R Bhattacharyya, DM Kovacs
Neurodegenerative Diseases 13 (2-3), 64-68, 2014
Genome-wide genetic screening in the mammalian CNS
MH Wertz, M Heiman
Genome Editing in Neurosciences, 31-39, 2017
A39 Precision machine-learning identifies a new paradigm along with a target database for therapeutic discovery in Huntington’s disease: molecular reprogramming to re-instate …
L Megret, B Gris, SS Nai, J Cevost, M Wertz, J Aaronson, J Rosinski, ...
Journal of Neurology, Neurosurgery & Psychiatry 93 (Suppl 1), A14-A14, 2022
A03 Precise machine-learning suggests that neuronal death in HD is mainly driven by the loss of homeostatic responses
L Mégret, B Gris, SS Nair, J Cevost, M Wertz, J Aaronson, J Rosinski, ...
Journal of Neurology, Neurosurgery & Psychiatry 92 (Suppl 1), A1-A2, 2021
Aberrant microRNA expression in spinal muscular atrophy motor neurons
MH Wertz
Harvard University, 2015
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